Body

BROCA sequencing approach evaluates all 24 genes implicated in breast cancer

Since 1994, many thousands of women with breast cancer from families severely affected with the disease have been tested for inherited mutations in BRCA1 and BRCA2. The vast majority of those patients were told that their gene sequences were normal.

Stopping transplant drugs before conception benefits fetus

Atlanta, GA (October 23, 2013)—Research suggests that fetal exposure to mycophenolic acid products (MPA)—which are drugs taken by transplant recipients to prevent rejection—may increase the risk of birth defects and spontaneous abortions. Results of this study will be presented at ASN Kidney Week 2013 November 5-10 at the Georgia World Congress Center in Atlanta, GA.

UNH researcher: Bees underwent massive extinction when dinosaurs did

DURHAM, N.H. -- For the first time ever, scientists have documented a widespread extinction of bees that occurred 65 million years ago, concurrent with the massive event that wiped out land dinosaurs and many flowering plants. Their findings, published this week in the journal PLOS ONE, could shed light on the current decline in bee species.

Oral bacteria create a 'fingerprint' in your mouth

COLUMBUS, Ohio – The bacteria in the human mouth – particularly those nestled under the gums – are as powerful as a fingerprint at identifying a person's ethnicity, new research shows.

Scientists identified a total of almost 400 different species of microbes in the mouths of 100 study participants belonging to four ethnic affiliations: non-Hispanic blacks, whites, Chinese and Latinos.

Men tend to walk slower when walking with romantic partners

When walking with female romantic partners, males tend to slow down by about 7%, according to new research published Oct 23 in the open-access journal PLOS ONE, by Cara Wall-Scheffler and colleagues at Seattle Pacific University.

Emotionally intelligent people may influence the emotions of others based on their own goals

Emotionally intelligent people have the ability to manipulate others to satisfy their own interest, according to new research published October 23 in the open-access journal PLOS ONE, by Yuki Nozaki and colleagues at Kyoto University.

Environmental factors help limit gene flow between different giraffe species

Giraffe species may only breed with each other based on the timing of rainfall in their local environments, according to new research published October 23 in the open-access journal PLOS ONE, by Henri Thomassen and colleagues at UCLA.

South African 'living stone' plant adapts to extreme conditions in new ways

A unique plant that lives underground uses multiple mechanisms to boost photosynthesis and offers new insights into how plants adapt to extreme conditions, according to new research published October 23 in the open-access journal PLOS ONE, by Katie Field and colleagues at the University of Sheffield and other institutions.

Child born with HIV still in remission after 18 months off treatment, experts report

A 3-year-old Mississippi child born with HIV and treated with a combination of antiviral drugs unusually early continues to do well and remains free of active infection 18 months after all treatment ceased, according to an updated case report published Oct. 23 in the New England Journal of Medicine.

Early findings of the case were presented in March 2013 during a scientific meeting in Atlanta, but the newly published report adds detail and confirms what researchers say is the first documented case of HIV remission in a child.

Long-term study links box jellyfish abundance, environmental variability at Waikiki Beach

You can almost set your watch to it.

A familiar sight to local beachgoers, the box jellyfish Alatina moseri is known for showing up in big numbers on Waikīkī Beach 8 to 12 days after each full moon.

Continuing a pioneering jellyfish beach count effort initiated in the 1980s by Honolulu lifeguard Landy Blair, researchers at the University of Hawai'i at Mānoa have published an analysis of 14 years of monthly jellyfish collection data.

Food additive may prevent spread of deadly new avian flu

A common food additive can block a deadly new strain of avian influenza virus from infecting healthy cells, report researchers at the University of Illinois at Chicago College of Medicine in the online journal, PLOS ONE.

The compound, in wide use as a preservative, binds to a part of the flu virus that has never been targeted by any existing antiviral drug, raising hopes for its effectiveness against multi-drug-resistant flu viruses.

USC researcher learns how to break a sweat

Without sweat, we would overheat and die. In a recent paper in the journal PLOS ONE, USC faculty member Krzysztof Kobielak and a team of researchers explored the ultimate origin of this sticky, stinky but vital substance — sweat gland stem cells.

Kobielak and his team used a system to make all of the sweat gland cells in a mouse easy to spot: labeling them with green fluorescent protein (GFP), which is visible under ultraviolet light.

Children's National researcher co-authors study on transitioning cystic fibrosis care

Washington, DC— Children's National pediatrician and researcher, Lisa Tuchman, MD, MPH, co-authored a new study on cystic fibrosis (CF) care that found patients had a less rapid decline in pulmonary function and no other significant health-related changes after transitioning from pediatric to adult care.

Cancer wasting due in part to tumor factors that block muscle repair, study shows

COLUMBUS, Ohio – A new study reveals that tumors release factors into the bloodstream that inhibit the repair of damaged muscle fibers, and that this contributes to muscle loss during cancer wasting. The condition, also called cancer cachexia, accompanies certain types of cancer, causes life-threatening loss of body weight and lean muscle mass, and is responsible for up to one-in-four cancer deaths. There is no treatment for the condition.

Diabetes drug metformin with chemo and radiation may improve outcomes in lung cancer patients

SYDNEY, AUSTRALIA—Treating aggressive lung cancer with the diabetes drug metformin along with radiation and chemotherapy may slow tumor growth and recurrence, suggests new preliminary findings from researchers at the Perelman School of Medicine at the University of Pennsylvania being presented during an oral abstract session October 28 at the 15th World Conference on Lung Cancer.