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Substances from African medicinal plants could help stop tumor growth

African medicinal plants contain chemicals that may be able to stop the spread of cancer cells. This is the conclusion of researchers following laboratory experiments conducted at Johannes Gutenberg University Mainz (JGU). The plant materials will now undergo further analysis in order to evaluate their therapeutic potential. "The active substances present in African medicinal plants may be capable of killing off tumor cells that are resistant to more than one drug.

British butterfly desperate for warm weather this summer

Butterflies are extremely sensitive to changes in temperature and new research has revealed that when summer weather turns bad the silver-spotted skipper battles for survival. The butterfly, which previously faced extinction from habitat loss, is recovering following conservation efforts but the recent cool wet summers in England have almost stalled its progress.

Self-fertilizing plants contribute to their own demise

TORONTO, ON – Many plants are self-fertilizing, meaning they act as both mother and father to their own seeds. This strategy – known as selfing – guarantees reproduction but, over time, leads to reduced diversity and the accumulation of harmful mutations. A new study published in the scientific journal Nature Genetics shows that these negative consequences are apparent across a selfing plant's genome, and can arise more rapidly than previously thought.

Potentially 'catastrophic' changes underway in Canada's northern Mackenzie River Basin: report

Canada's Mackenzie River basin -- among the world's most important major ecosystems -- is poorly studied, inadequately monitored, and at serious risk due to climate change and resource exploitation, a panel of international scientists warn today.

Nearly a fifth of designated drivers are impaired

PISCATAWAY, NJ – They may volunteer to be the one to get their friends home safely, but "designated drivers" often drink—even to a level that impairs them behind the wheel, according to a report in the July issue of the Journal of Studies on Alcohol and Drugs.

The study, of more than 1,000 bar patrons, found that approximately 40 percent of designated drivers had downed alcohol. What's more, most of those drinkers had blood alcohol levels that could impair their driving.

Women can be screened years later than men with 'virtual colonoscopy'

A new study has found that women can be screened for colorectal cancer at least five to 10 years later than men when undergoing an initial "virtual colonoscopy." Published early online in CANCER, a peer-reviewed journal of the American Cancer Society, the findings may help establish guidelines for the use of this screening technique, which is less invasive than a traditional colonoscopy.

When calculating cell-growth thermodynamics, reconsider using the Gibbs free energy equation

A forthcoming article in The Quarterly Review of Biology provides the basis for an argument against using the Gibbs free energy equation to accurately determine the thermodynamics of microbial growth.

How to control maple tree pests using integrated pest management

Many maple trees share a suite of important arthropod pests that have the potential to reduce the trees' economic and aesthetic value. Now a new open-access article in the Journal of Integrated Pest Management offers maple tree owners information about the biology, damage, and management for the most important pests of maples with an emphasis on integrated pest management (IPM) tactics for each pest.

MRI detects early effects of chemotherapy on children's hearts

MRI scans of children who have had chemotherapy can detect early changes in their hearts finds research in biomed Central's open access journal Journal of Cardiovascular Magnetic Resonance.

Investigation into safety of new diabetes drugs -- will manufacturers release their data?

The BMJ and Channel 4 Dispatches investigated and found that evidence suggesting potential harm from the drugs in industry studies has not been published.

Some independent studies challenge the conclusions of the drugs manufacturers' own research. Now some medical experts and patient groups are calling on the pharmaceutical companies to be more transparent in reporting of study data and to enter into dialogue about safety concerns.

As a result, millions of patients around the world have not been fully informed about some of the possible risks.

Interferon-beta aids balance and movement in mice with spinocerebellar ataxia 7

Paris, France: The group of genetic conditions known as spinocerebellar ataxias currently have no treatment or cure and are always fatal, in the case of affected children at an early age. Symptoms include a progressive lack of co-ordination of gait, and poor co-ordination of hands, speech and eye movements, due to a failure of co-ordination of muscle movements.

The duck genome provides new insight into fighting bird flu

Shenzhen, China - The duck genome consortium, consisted of scientists from China Agricultural University, BGI, University of Edinburgh and other institutes has completed the genome sequencing and analysis of the duck (Anas platyrhynchos), one principal natural host of influenza A viruses, which caused a new epidemic in China since this February. This work reveals some noteworthy conclusions and provides an invaluable resource for unraveling the interactive mechanisms between the host and influenza viruses.

Scientists identify potential drug target for treatment-resistant anemias

CAMBRIDGE, Mass. (June 9, 2013) – Researchers at Whitehead Institute have identified a protein that is the target of glucocorticoids, the drugs that are used to increase red blood cell production in patients with certain types of anemia, including those resulting from trauma, sepsis, malaria, kidney dialysis, and chemotherapy. The discovery could spur development of drugs capable of increasing this protein's production without causing the severe side effects associated with glucocorticoids.

Rare mitochondrial mutations -- maybe not so rare?

Paris, France: French scientists have discovered that supposedly rare mutations in the mitochondria, the 'power plants' of human cells responsible for creating energy, account for more than 7% of patients with a mitochondrial disease manifesting itself as a respiratory deficiency. Their data emphasise the need for comprehensive analysis of all the mitochondrial DNA (mtDNA) in patients suspected as having a mitochondrial disease, and this should include children, a researcher will tell the annual conference of the European Society of Human Genetics today (Sunday).

Danish researchers expose new cause of life-threatening disease

Danish researchers have just published findings that explain a previously unknown mechanism used by cells to communicate with one another. The research significantly contributes to understanding why some children are born with malformations and why children and adults may develop life-threatening diseases.