Body

LA JOLLA, CA—Experiment after experiment confirms that a diet on the brink of starvation expands lifespan in mice and many other species. But the molecular mechanism that links nutrition and survival is still poorly understood. Now, researchers at the Salk Institute for Biological Studies have identified a pivotal role for two enzymes that work together to determine the health benefits of diet restriction.

BOSTON--Dana-Farber Cancer Institute scientists' discovery of a cancer-causing gene – the first in its family to be linked to cancer – demonstrates how the panoramic view of genomics and the close-up perspective of molecular biology are needed to determine which genes are involved in cancer and which are mere bystanders. The findings are reported in the June 25 issue of the journal Nature.

La Jolla, CA, June 24, 2009 -- A team of scientists from The Scripps Research Institute, Katholeike Universiteit Leuven, and the University of Antwerp, Belgium, among other institutions, has created a genetically modified fruit fly that mimics key features of Charcot-Marie-Tooth disease, a common neurodegenerative disorder that strikes about one out of every 2,500 people in the United States.

GAINESVILLE — Researchers have identified a genetic glitch that could lead to development of neuroblastoma, a deadly form of cancer that typically strikes children under 2.

Two University of Florida scientists are part of the multicenter team of researchers that made the discovery, which could pave the way for better treatments that target the disease, according to findings published Wednesday in the journal Nature.

A two-tiered scanning-protocol for inspecting all containers at international ports could be the most affordable approach to ensuring containers moving through the global transportation system are not carrying nuclear bombs, according to a paper being presented at a services special interest group meeting of the Institute for Operations Research and the Management Sciences (INFORMS®).

Cold Spring Harbor, N.Y. – A math-based game that has taken the world by storm with its ability to delight and puzzle may now be poised to revolutionize the fast-changing world of genome sequencing and the field of medical genetics, suggests a new report by a team of scientists at Cold Spring Harbor Laboratory (CSHL). The report will be published as the cover story in the July 1st issue of the journal Genome Research.

Girls typically are less physically active than boys, but a Kansas State University researcher has found that organizations like Girl Scouts provide an ideal setting to get girls moving early in life and to develop lifelong healthy habits.

Richard Rosenkranz, assistant professor in human nutrition at K-State, did a study using interventions with Girl Scout troops. He trained group leaders to instruct exercise sessions and promote healthful eating, and in effect taught the girls about a healthy lifestyle and increased their participation in exercise activities.

Tobacco acts as a precipitating factor for headaches, specifically migraines. This is indicated in a study which shows that smokers have more migraine attacks and that smoking more than five cigarettes a day triggers this headache. The work has appeared in the Journal of Headache and Pain.

While cancer touches the lives of many humans, it is also a major threat to wild animal populations as well, according to a recent study by the Wildlife Conservation Society (WCS).

A newly published paper in the July edition of Nature Reviews Cancer compiles information on cancer in wildlife and suggests that cancer poses a conservation threat to certain species. The WCS authors highlight the critical need to protect both animals and people through increased health monitoring.

There is minimal data evaluating the prevalence of GERD complications in any United States general population, other than non-Hispanic whites. Presently, it is thought that such complications occur less frequently in African-Americans than in non-Hispanic whites. A research group in Jacksonville, FL investigated the prevalence of reflux esophagitis between non-Hispanic whites and African-Americans. The distribution of esophagitis severity and its complications were equivalent between groups, except for Barrett's esophagus.

To stretch a supply of salt generally means using it sparingly.

But researchers from Sandia National Laboratories and the University of Pittsburgh were startled when they found they had made the solid actually physically stretch.

"It's not supposed to do that," said Sandia principal investigator Jack Houston. "Unlike, say, gold, which is ductile and deforms under pressure, salt is brittle. Hit it with a hammer, it shatters like glass."

Global warming will likely mean more unpredictable weather, scientists say, and a new study by researchers at the University of Georgia pins down, possibly for the first time, how drought conditions in an area's fall and winter may effect tornado activity the following spring.

The study, published today in the journal Environmental Research Letters, is specific to Georgia and the Southeast, but further study could reveal patterns that might make this more general—including the already tornado-prone Great Plains.

June 24/Geneva — Climate has always presented a challenge to farmers, herders, fishermen and others whose livelihoods are closely linked to their environment, particularly those in poor areas of the world. A type of insurance, called index insurance, now offers significant opportunities as a climate-risk management tool in developing countries, according to a new publication launched today during a workshop at the Global Humanitarian Forum (GHF) in Geneva.