Body

DURHAM, N.C. – New guidelines for using statins to treat high cholesterol and prevent cardiovascular disease are projected to result in 12.8 million more U.S. adults taking the drugs, according to a research team led by Duke Medicine scientists.

The findings for the first time quantify the impact of the American Heart Association's new guidelines, which were issued in November and generated both controversy and speculation about who should be given a prescription for statins.

AMHERST, Mass. ¬– A first-of-its-kind satellite tagging study of migrating New England leatherback turtles in the North Atlantic offers a greatly improved understanding of their seasonal high-use habitats, diving activity and response to key ocean and environmental features in relation to their search behavior. Leatherbacks are considered endangered species in all the world's oceans.

LAKE SUCCESS, NY – Two North Shore-LIJ Cancer Institute doctors, world-renowned for their research in chronic lymphocytic leukemia (CLL), weigh in on a German study of a new drug therapy for CLL in the March 20 edition of the New England Journal of Medicine, the North Shore-LIJ Health System announced today.

ITHACA, N.Y. – During Pleistocene era climate changes, neotropical orchid bees that relied on year-round warmth and wet weather found their habitats reduced by 30 to 50 percent, according to a Cornell University study that used computer models and genetic data to understand bee distributions during past climate changes.

Teaching people how to flavor food with spices and herbs is considerably more effective at lowering salt intake than having them do it on their own, according to research presented at the American Heart Association's Epidemiology & Prevention/Nutrition, Physical Activity & Metabolism Scientific Sessions 2014.

In the first phase of the study, 55 volunteers ate a low-sodium diet for four weeks. Researchers provided all foods and calorie-containing drinks. Salt is the main source of sodium in food.

Industry-sponsored, academic research leads to innovative patents and licenses, says a new analysis led by Brian Wright, University of California, Berkeley professor of agricultural and resource economics.

The finding calls into question assumptions that corporate support skews science toward inventions that are less accessible and less useful to others than those funded by the government or non-profit organizations.

The analysis, based on a study of two decades of records from the University of California system, is in today's science journal Nature.

Researchers from the Santa Fe Institute and the Smithsonian Institution have pieced together a highly detailed picture of feeding relationships among 700 mammal, bird, reptile, fish, insect, and plant species from a 48 million year old lake and forest ecosystem.

What immune response should a vaccine elicit to prevent HIV infection? Two studies published online today bring scientists closer to answering this question by identifying previously unrecognized attributes of antibodies that appear to have reduced the risk of HIV infection in the only clinical trial to show efficacy, albeit modest, of an experimental vaccine regimen in people.

Beverly, MA, March 19, 2014 – Long-term survivors after esophagectomy with gastric pull-up can enjoy a satisfying meal and good quality of life according to a new study from a team of researchers at the University of Southern California Keck School of Medicine, Los Angeles. This study concluded that pessimism about the long-term quality of life after an esophagectomy on the part of treating physicians and patients is unwarranted. It is published in the Journal of Thoracic and Cardiovascular Surgery, an official publication of the American Association for Thoracic Surgery.

Hungry dogs would be expected to choose alternatives leading to more food rather than less food. But just as with humans and monkeys, they sometimes show a "less is more" effect. Thus conclude Kristina Pattison and Thomas Zentall of the University of Kentucky in the US, who tested the principle by feeding baby carrots and string cheese to ten dogs of various breeds. The findings are published in Springer's journal Animal Cognition.

Researchers studying intestinal bacteria in newborns have characterized the gut bacteria of premature infants who go on to develop sepsis, a serious and potentially life-threatening condition caused by bacteria in the bloodstream. Their findings suggest new strategies for the early detection and prevention of severe bloodstream infections.

Glasgow, UK: Women whose breast cancer has spread to just a few lymph nodes under their arm are less likely to have their disease recur or to die from it if they have radiotherapy after mastectomy, according to new research to be presented at the European Breast Cancer Conference (EBCC-9) on Thursday and published in The Lancet today (Wednesday). [1]

PHOENIX, Ariz. — March 19, 2014 — In a scientific first, the fusion of two genes, ALK and EML4, has been identified as the genetic driver in an aggressive type of thyroid cancer, according to a study by the Translational Genomics Research Institute (TGen).

These groundbreaking findings are based on genetic sequencing of tumor cells from a 62-year-old patient with an aggressive tall cell variant of papillary thyroid cancer, according to the study published Tuesday, March 18, in the World Journal of Surgery, the official journal of the International Society of Surgery.

DURHAM, N.C. – A multi-national research team led by Duke Medicine scientists has identified a subclass of antibodies associated with an effective immune response to an HIV vaccine.

The finding, reported in the March 19, 2014, issue of the journal Science Translational Medicine, helps explain why a combination of two vaccines was able to show some effect, when one vaccine alone did not. The study also provides key insights that could aid development of new vaccines.

New research shows an alternative DNA test offers clinically relevant genetic information to identify why a miscarriage may have occurred years earlier. Researchers were able to identify chromosomal variants and abnormalities in nearly 50 percent of the samples. This first-of-its-kind study was conducted by researchers from Montefiore Medical Center and the Albert Einstein College of Medicine of Yeshiva University.