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Newborn health improves despite income gap

The U.S. economic inequality gap has been widening for decades, and research shows that maternal disadvantage may have health consequences for newborns. A review of recent economic research, however, finds that the health of newborns has actually improved nationally in recent years, despite data that would suggest otherwise.

Ancient DNA ends Aussie claim to kiwi origins

Australia can no longer lay claim to the origins of the iconic New Zealand kiwi following University of Adelaide research published in the journal Science today showing the kiwi's closest relative is not the emu as was previously thought.

Instead, the diminutive kiwi is most closely related to the extinct Madagascan elephant bird – a 2-3 metre tall, 275 kg giant. And surprisingly, the study concluded, both of these flightless birds once flew.

Scientists identify potential vaccine candidate for pediatric malaria

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Delegating the dirty work is a key to evolution

EAST LANSING, Mich. — We have hundreds of types of cells in our bodies – everything from red blood cells to hair follicles to neurons. But why can't most of them create offspring for us?

New research at Michigan State University suggests that separating germ cells – sperm and eggs –from somatic cells – all other cells – preserves the genetic building blocks while allowing organisms to flourish in a somewhat hazardous environment.

Researchers identify key mechanism in metabolic pathway that fuels cancers

DALLAS – May 22, 2014 – In a breakthrough discovery at the Children's Medical Center Research Institute at UT Southwestern (CRI), a research team led by Ralph DeBerardinis, M.D., Ph.D., has taken a significant step in cracking the code of an atypical metabolic pathway that allows certain cancerous tumors to thrive, providing a possible roadmap for defeating such cancers.

Antibiotic crisis needs united global response, experts say

Growing resistance to antibiotics and other drugs demands a coordinated global response on the same scale as efforts to address climate change, experts say.

Without an international commitment to tackle the issue, the world faces a future in which simple infections that have been treatable for decades become deadly diseases, they warn.

Resistance to antibiotics to tackle bacterial infections and antimicrobial drugs used to treat parasites, viruses and fungi is spreading at an alarming rate. Treatment for many infectious diseases is now reliant on just one or two drugs.

New details on microtubules and how the anti-cancer drug Taxol works

A pathway to the design of even more effective versions of the powerful anti-cancer drug Taxol has been opened with the most detailed look ever at the assembly and disassembly of microtubules, tiny fibers of tubulin protein that form the cytoskeletons of living cells and play a crucial role in mitosis.

Which way is up?

What do sled dogs and cell clusters have in common? According to research by UC Santa Barbara's Denise Montell, they both travel in groups and need a leader to make sure they all follow in the same direction.

Montell, Duggan Professor of Molecular Cellular and Developmental Biology, and colleagues worked on three independent projects involving E-cadherin, a protein found in epithelial cells throughout the body. The researchers used fruit-fly ovaries to uncover the role played by E-cadherin in collective cell migration. Their findings are reported today in the journal Cell.

RaDAR guides proteins into the nucleus

May 22, 2014, New York, NY – A Ludwig Cancer Research study has identified a novel pathway by which proteins are actively and specifically shuttled into the nucleus of a cell. Published online today in Cell, the finding captures a precise molecular barcode that flags proteins for such import and describes the biochemical interaction that drives this critically important process. The discovery could help illuminate the molecular dysfunction that underpins a broad array of ailments, ranging from autoimmune diseases to cancers.

Wondering about the state of the environment? Just eavesdrop on the bees

In all, the researchers "eavesdropped" on 5,484 dances to find that the best forage within the 94 km2 of mixed urban-rural landscape included in the study—as far as bees and, by extension, other insect pollinators are concerned—is a place called Castle Hill, which happened to be the only National Nature Reserve in the area. More broadly, High Level agri-environment schemes were the best places for bees.

Blocking pain receptors found to extend lifespan in mammals

Chronic pain in humans is associated with worse health and a shorter lifespan, but the molecular mechanisms underlying these clinical observations have not been clear. A study published by Cell Press May 22nd in the journal Cell reveals that the activity of a pain receptor called TRPV1 regulates lifespan and metabolic health in mice. The study suggests that pain perception can affect the aging process and reveals novel strategies that could improve metabolic health and longevity in humans.

Genes discovered linking circadian clock with eating schedule

LA JOLLA—For most people, the urge to eat a meal or snack comes at a few, predictable times during the waking part of the day. But for those with a rare syndrome, hunger comes at unwanted hours, interrupts sleep and causes overeating.

New technology may help identify safe alternatives to BPA

Numerous studies have linked exposure to bisphenol A (BPA) in plastic, receipt paper, toys, and other products with various health problems from poor growth to cancer, and the FDA has been supporting efforts to find and use alternatives. But are these alternatives safer? Researchers reporting in the Cell Press journal Chemistry & Biology have developed new tests that can classify such compounds' activity with great detail and speed. The advance could offer a fast and cost-effective way to identify safe replacements for BPA.

Gene behind unhealthy adipose tissue identified

Researchers at Karolinska Institutet in Sweden have for the first time identified a gene driving the development of pernicious adipose tissue in humans. The findings imply, which are published in the scientific journal Cell Metabolism, that the gene may constitute a risk factor promoting the development of insulin resistance and type 2 diabetes.

Computer models helping unravel the science of life?

Scientists have developed a sophisticated computer modelling simulation to explore how cells of the fruit fly react to changes in the environment.

The research, published today in the science journal Cell, is part of an on-going study at The Universities of Manchester and Sheffield that is investigating how external environmental factors impact on health and disease.