Body

Scientists discover potential new target for cancer immunotherapy

HOUSTON -- Scientists have found a way to target elusive cells that suppress immune response, depleting them with peptides that spare other important cells and shrink tumors in preclinical experiments, according to a paper published online by Nature Medicine.

Researchers map the epic evolution of a 'ring species'

The Greenish Warbler, long considered an idealized example of a single species that diverged into two as it expanded its range, has a much more checkered family history than biologists previously realized.

Powerful new way to treat HER2-positive breast cancer validated

Cold Spring Harbor, NY -- Scientists at Cold Spring Harbor Laboratory (CSHL) today report a discovery that they hope will lead to the development of a powerful new way of treating an aggressive form of breast cancer.

Slowing the insect invasion: Wood packaging sanitation yields US $11.7 billion net benefit

The emerald ash borer (Agrilus plantipenis), a recent insect immigrant to North America carried in with the wooden packing material of imported goods, is projected to cause over a billion dollars in damages annually over the next decade. International standards now require expensive fumigation or heat treatment of wood pallets and crates to prevent the inadvertent import of new wood boring insect pests in shipping materials.

Untangling whole genomes of individual species from a microbial mix

BETHESDA, MD – May 23, 2014 – A new approach to studying microbes in the wild will allow scientists to sequence the genomes of individual species from complex mixtures. It marks a big advance for understanding the enormous diversity of microbial communities —including the human microbiome. The work is described in an article published May 22 in Early Online form in the journal G3: Genes|Genomes|Genetics, published by the Genetics Society of America.

Poor diet before pregnancy is linked with preterm birth

University of Adelaide research has for the first time confirmed that women who eat a poor diet before they become pregnant are around 50% more likely to have a preterm birth than those on a healthy diet.

Researchers at the University of Adelaide's Robinson Research Institute investigated the dietary patterns of more than 300 South Australian women to better understand their eating habits before pregnancy.

Wound-healing role for microRNAs in colon offer new insight to inflammatory bowel diseases

DALLAS – May 23, 2014 – A microRNA cluster believed to be important for suppressing colon cancer has been found to play a critical role in wound healing in the intestine, UT Southwestern cancer researchers have found.

The findings, first discovered in mice and later reproduced in human cells, could provide a fresh avenue for investigating chronic digestive diseases and for potentially repairing damage in these and other disease or injury settings.

Social marketing at the movies

Word-of-mouth marketing is recognized as a powerful route from long-tail sales to blockbuster, whether one is talking about the latest fishy ice cream flavor or a Hollywood romantic comedy. In the age of social media and online networking sites, such as Twitter and Facebook, the potential for spreading the word could mean the difference between consumers seeing a product as the best thing since sliced bread or the most rotten of tomatoes.

Breakthrough method for making Janus or patchy capsules

Hollow capsules that have a selectively permeable shell are promising candidates as tiny containers for molecules, particles or bubbles, and are becoming increasingly important in a wide variety of applications. But making these kinds of capsules with more than one kind of substance on their shells has been challenging – until now.

The protective milk shot

Antibodies against C. suis are transferred via the sow's very first milk to the piglets immediately after birth. This was discovered by veterinarian and parasitologist Lukas Schwarz and his colleagues in 2013. These findings prompted the researchers at the Institute for Parasitology to look for a way to increase the level of these antibodies in sows. The ultimate goal was to provide the piglets with as much antibodies as possible via their mother's milk during the first few days of life.

Piglets from infected mothers are healthier

Rapid evolution aids spread of exotic plant species

A team of Belgian biologists led by researchers at KU Leuven has provided the first genetic evidence that rapid evolution can help non-native plant species spread in new environments. Using samples of centuries-old herbaria and DNA analysis, the researchers reconstructed the genetic adaptations undergone by the Pyrenean rocket prior to its rapid spread in Belgium.

Lack of plant diversity spurs cankerworm damage in cities

Research from North Carolina State University finds that a lack of plant diversity is a key contributor to the widespread defoliation caused by cankerworms in cities, and highlights the role that increasing diversity can play in limiting future damage.

Fall cankerworms (Alsophila pometaria) are caterpillars that are native to the eastern United States and hatch in early spring. The cankerworms defoliate trees and other plants, eating new leaves as they emerge – which is both unsightly and can ultimately kill the plants.

Mapping atherosclerotic arteries: Combined approach developed

A new method allows calcified and constricted blood vessels to be visualized with micrometer precision, and can be used to design containers for targeted drug delivery. Within the project "NO-stress", materials scientists from the Medical Faculty of the University of Basel combined cutting-edge-imaging techniques to visualize and quantify the constrictions caused by atherosclerosis.

Bacterial adaptation contributes to pneumococcal threat in sickle cell disease patients

Researchers have identified differences in the genetic code of pneumococcal bacteria that may explain why it poses such a risk to children with sickle cell disease and why current vaccines don't provide better protection against the infection. St. Jude Children's Research Hospital scientists led the study, which appeared earlier this month in the journal Cell Host & Microbe.

Breakthrough in RSV research to help infected children

Researchers at Le Bonheur Children's Hospital and the University of Tennessee Health Science Center announced results today from a clinical trial of a drug shown to safely reduce the viral load and clinical illness of healthy adult volunteers intranasally infected with respiratory syncytial virus (RSV).