Body

New genomic research led by UC San Francisco (UCSF) scientists reveals that two common gene variants that lead to longer telomeres, the caps on chromosome ends thought by many scientists to confer health by protecting cells from aging, also significantly increase the risk of developing the deadly brain cancers known as gliomas.

Monitoring the drug concentration in patients is critical for effective treatment, especially in cases of cancer, heart disease, epilepsy and immunosuppression after organ transplants. However, current methods are expensive, time-consuming, and require dedicated personnel and infrastructure away from the patient. Publishing in Nature Chemical Biology, scientists at EPFL introduce novel light-emitting sensor proteins that can quickly and simply show how much drug is in a patient's bloodstream by changing the color of their light.

Citrus is the world's most widely cultivated fruit crop. In the U.S. alone, the citrus crop was valued at over $3.1 billion in 2013. Originally domesticated in Southeast Asia thousands of years ago before spreading throughout Asia, Europe, and the Americas via trade, citrus is now under attack from citrus greening, an insidious emerging infectious disease that is destroying entire orchards.

(Santa Barbara, Calif.) — Scientists at UC Santa Barbara have designed a nanoparticle that has a couple of unique — and important — properties. Spherical in shape and silver in composition, it is encased in a shell coated with a peptide that enables it to target tumor cells. What's more, the shell is etchable so those nanoparticles that don't hit their target can be broken down and eliminated. The research findings appear today in the journal Nature Materials.

"It doesn't take much to see that the problems of three little people doesn't add up to a hill of beans in this crazy world," Humphrey Bogart famously said in the movie Casablanca. For the farmers and breeders around the world growing the common bean, however, ensuring that there is an abundant supply of this legume is crucial, both for its importance in cropping systems to ensure plant vitality and for food security. Moreover, the U.S.

UPTON, NY -- Sometimes a cell has to die-when it's done with its job or inflicted with injury that could otherwise harm an organism. Conversely, cells that refuse to die when expected can lead to cancer. So scientists interested in fighting cancer have been keenly interested in learning the details of "programmed cell death." They want to understand what happens when this process goes awry and identify new targets for anticancer drugs.

Philadelphia – Though Twitter boats 645 million users across the world, only 14 percent of health policy researchers reported using Twitter – and approximately 20 percent used blogs and Facebook – to communicate their research findings over the past year, according to a new study from the Perelman School of Medicine at the University of Pennsylvania. In contrast, sixty-five percent used traditional media channels, such as press releases or media interviews.

Infants exposed to a diverse range of bacterial species in house dust during the first year of life appear to be less likely to develop asthma in early childhood, according to a new study published online on June 6, 2014, in the Journal of Allergy and Clinical Immunology.

Children who were neither allergic nor prone to wheezing as three-year-olds were the most likely to have been exposed to high levels of bacteria, and paradoxically, to high levels of common allergens.

BUFFALO, N.Y. – Motorists in Los Angeles, San Francisco and other gridlocked cities could learn something from the fruit fly.

Scientists have found that cellular blockages, the molecular equivalent to traffic jams, in nerve cells of the insect's brain can form and dissolve in 30 seconds or less.

The findings, presented in the journal PLOS ONE, could provide scientists much-needed clues to better identify and treat neurodegenerative diseases such as Alzheimer's and Huntington's.

JACKSONVILLE, Fla. — June 6, 3014 — An optical blood oxygen sensor attached to an endoscope is able to identify pancreatic cancer in patients via a simple lendoscopic procedure, according to researchers at Mayo Clinic in Florida.

An international team of researchers comprised of Thomas Wesener, Museum Koenig, Bonn, Daniel Le, Field Museum, Chicago and Stephanie Loria, American Museum of Natural History, New York, discovered seven new species of chirping giant pill-millipedes on Madagascar. The study was published in the open access journal ZooKeys.

A team of biologists from the University of Leicester has solved a mystery surrounding how plants have sex.

The researchers have discovered a pair of proteins made by flowering plants that are vital for the production of the sperm present within each pollen grain.

Scientists already knew that flowering plants, in contrast to animals, require not one, but two sperm cells for successful fertilisation: one to join with the egg cell to produce the embryo and one to join with a second cell to produce the nutrient-rich endosperm inside the seed.

This news release is available in German.

The Kaposi's sarcoma-associated herpesvirus (KSHV), a gammaherpesvirus that can cause multiple forms of cancer, establishes lifelong infections within the body. To do so the virus has to find a way to modulate the immune system of its host.

Local direct public funding provided through grants for the arts in Chicago is low compared to peer regions in both total dollar and per capita terms, according to a new report from the Cultural Policy Center at the University of Chicago.

Researchers at the University of California, San Diego School of Medicine have mapped the transmission network of human immunodeficiency virus (HIV) in San Diego. The mapping of HIV infections, which used genetic sequencing, allowed researchers to predictively model the likelihood of new HIV transmissions and identify persons at greatest risk for transmitting the virus.

The findings are published online in the June 5 issue of the journal PLOS ONE.