Body

ADHD-air pollution link

Prenatal exposure to polycyclic aromatic hydrocarbons, or PAH, a component of air pollution, raises the odds of behavior problems associated with attention deficit hyperactivity disorder, or ADHD, at age 9, according to researchers at the Columbia Center for Children's Environmental Health at the Mailman School of Public Health. Results are published online in the journal PLOS ONE.

Small New Zealand population initiated rapid forest transition c. 750 years ago

Human-set fires by a small Polynesian population in New Zealand ~750 years ago may have caused fire-vulnerable forests to shift to shrub land over decades, rather than over centuries, as previously thought, according to a study published November 5, 2014 in the open-access journal PLOS ONE by David McWethy from Montana State University and colleagues.

Older men less likely to receive osteoporosis screening and treatment following a bone fracture

ROSEMONT, Ill.—Osteoporosis, a common condition causing progressive bone loss and increased fracture risk, is primarily thought of as a disease affecting older women. And yet, up to one in four men over age 50 will break a bone due to osteoporosis. A study in the November 5 issue of the Journal of Bone & Joint Surgery (JBJS) found that men were three times less likely than women to undergo bone mass density (BMD) testing following a broken wrist (distal radius fracture) and seven times less likely to begin treatment for osteoporosis.

Osteoporosis, not just a woman's disease

BOSTON – Each year nearly two million Americans suffer osteoporosis-related fractures, and as the population ages that number is expected to increase dramatically, placing a major burden on the health care system. While osteoporosis prevention and treatment efforts have historically been focused on post-menopausal women, a new study from Beth Israel Deaconess Medical Center (BIDMC) suggests that critical opportunities are being lost by not focusing more attention on bone loss and fracture risk in older men.

Genesis of genitalia

When it comes to genitalia, nature enjoys variety. Snakes and lizards have two. Birds and people have one. And while the former group's paired structures are located somewhat at the level of the limbs, ours, and the birds', appear a bit further down. In fact, snake and lizard genitalia are derived from tissue that gives rise to hind legs, while mammalian genitalia are derived from the tail bud. But despite such noteworthy contrasts, these structures are functionally analogous and express similar genes.

How do these equivalent structures arise from different starting tissues?

Bone drug should be seen in a new light for its anti-cancer properties

Australian researchers have shown why calcium-binding drugs commonly used to treat people with osteoporosis, or with late-stage cancers that have spread to bone, may also benefit patients with tumours outside the skeleton, including breast cancer.

Several clinical trials – where women with breast cancer were given these drugs (bisphosphonates) alongside normal treatment for early-stage disease – showed that they can confer a 'survival advantage' and inhibit cancer spread in some women, although until now no-one has understood why.

Clearing a path for electrons in polymers: Closing in on the speed limits

Researchers from the University of Cambridge have identified a class of low-cost, easily-processed semiconducting polymers which, despite their seemingly disorganised internal structure, can transport electrons as efficiently as expensive crystalline inorganic semiconductors.

Risk stratification model may aid in lung cancer staging and treatment decisions

DENVER – A risk stratification model based on lymph node characteristics confirms with a high level of confidence the true lack of lung cancer in lymph nodes adequately sampled with endobronchial ultrasound-guided transbronchial needle aspiration and classified as negative.

Readmission rates above average for survivors of septic shock, Penn study finds

PHILADELPHIA –A diagnosis of septic shock was once a near death sentence. At best, survivors suffered a substantially reduced quality of life.

Penn Medicine researchers have now shown that while most patients now survive a hospital stay for septic shock, 23 percent will return to the hospital within 30 days, many with another life-threatening condition -- a rate substantially higher than the normal readmission rate at a large academic medical center. The findings are published in the new issue of Critical Care Medicine.

High rate of insomnia during early recovery from addiction

November 5, 2014 – Insomnia is a "prevalent and persistent" problem for patients in the early phases of recovery from the disease of addiction—and may lead to an increased risk of relapse, according to a report in the November/December Journal of Addiction Medicine, the official journal of the American Society of Addiction Medicine.

IU researchers: Protein linked to aging identified as new target for controlling diabetes

INDIANAPOLIS -- Indiana University School of Medicine researchers have identified a small protein with a big role in lowering plasma glucose and increasing insulin sensitivity. Their research appeared online today in Diabetes, the journal of the American Diabetes Association.

How corals can actually benefit from climate change effects

Researchers from Northeastern University's Marine Science Center and the University of North Carolina at Chapel Hill have found that moderate ocean acidification and warming can actually enhance the growth rate of one reef-​​building coral species. Only under extreme acidification and thermal conditions did calcification decline.

Their work, which was published Wednesday in the journal Proceedings of the Royal Society B: Biological Sciences, is the first to show that some corals may benefit from moderate ocean acidification.

Engineered for tolerance, bacteria pump out higher quantity of renewable gasoline

WASHINGTON, DC—November 4, 2014—An international team of bioengineers has boosted the ability of bacteria to produce isopentenol, a compound with desirable gasoline properties. The finding, published in mBio®, the online open-access journal of the American Society for Microbiology, is a significant step toward developing a bacterial strain that can yield industrial quantities of renewable bio-gasoline.

Shape of things to come in platelet mimicry

CLEVELAND—Artificial platelet mimics developed by a research team from Case Western Reserve University and University of California, Santa Barbara, are able to halt bleeding in mouse models 65 percent faster than nature can on its own.

CNIO researchers create a mouse model that reproduces noonan syndrome

Noonan syndrome is a rare disease that is characterised by a set of pathologies, including heart, facial and skeletal alterations, pulmonary stenosis, short stature, and a greater incidence of haematological problems (mainly juvenile myeloid leukaemia, or childhood leukaemia). There is an estimated incidence of 1 case for every 1,000–2,500 births, and calculations show some 20,000–40,000 people suffer from the disease in Spain.