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New test will combat major cause of preventable blindness in Africa

Seattle, November 2, 2014—A new test will accelerate global progress toward eliminating onchocerciasis, a leading cause of preventable blindness in Africa. PATH, an international nonprofit health organization, today announced the availability of the SD BIOLINE Onchocerciasis IgG4 rapid test, manufactured and distributed by Standard Diagnostics, Inc. (SD). Designed for use in disease surveillance, the antibody-based test is faster, easier-to-use, and more acceptable to impacted communities than the current option.

Study reveals startling decline in European birds

Bird populations across Europe have experienced sharp declines over the past 30 years, with the majority of losses from the most common species, say the University of Exeter, the RSPB and the Pan-European Common Bird Monitoring Scheme (PECBMS) in a new study. However numbers of some less common birds have risen.

Sea sponge drug could boost advanced breast cancer survival by 5 extra months

THE cancer drug eribulin, originally developed from sea sponges, could give women with advanced triple negative breast cancer an average of five extra months of life, according to research presented at the National Cancer Research Institute (NCRI) Cancer Conference in Liverpool today (Monday).

The Lancet Diabetes & Endocrinology: Weight loss surgery substantially reduces the risk of developing type 2 diabetes

Bariatric (weight loss) surgery, such as gastric bypass or gastric banding, could reduce the risk of developing type 2 diabetes by around 80% in obese people, compared with standard care, new research published in The Lancet Diabetes & Endocrinology journal suggests.

Getting more out of nature: Genetic toolkit finds new maximum for crop yields

Cold Spring Harbor, NY – Scientists at Cold Spring Harbor Laboratory (CSHL) today announced a new way to dramatically increase crop yields by improving upon Mother Nature's offerings. A team led by Associate Professor Zachary Lippman, in collaboration with Israeli colleagues, has discovered a set of gene variations that can boost fruit production in the tomato plant by as much as 100%.

Study: 'Wimpy' antibody protects against kidney disease in mice

CINCINNATI—An antibody abundant in mice and previously thought to offer poor assistance in fighting against infection may actually play a key role in keeping immune responses in check and preventing more serious self-inflicted forms of kidney disease, researchers say.

Improving imaging of cancerous tissues by reversing time

As a child, it was fascinating to put a flashlight up to our palms to see the light shine through the hand. Washington University in St. Louis engineers are using a similar idea to track movement inside the body's tissues to improve imaging of cancerous tissues and to develop potential treatments.

Lihong Wang, PhD, the Gene K. Beare Distinguished Professor of Biomedical Engineering at the School of Engineering & Applied Science is applying a novel time-reversal technology that allows researchers to better focus light in tissue, such as muscles and organs.

Mutant models

Nate Silver and Richard Feynman walk into a bar and bump into a biologist . . .

While this may sound like the setup to some late-night nerd sketch, researchers have taken this premise and applied it to an increasingly cumbersome problem in modern biology, namely, finding meaning in the rising oceans of genomic data.

In this specific instance, the data comprisesreams of cancer mutations that genome-wide studies are publishing at a dizzying rate. The challenge is finding new and efficient ways to parse the signal from the noise (and there is no shortage of noise).

New technique efficiently turns antibodies into highly tuned 'nanobodies'

Antibodies, in charge of recognizing and homing in on molecular targets, are among the most useful tools in biology and medicine. Nanobodies – antibodies' tiny cousins – can do the same tasks, for example marking molecules for research or flagging diseased cells for destruction. But, thanks to their comparative simplicity nanobodies offer the tantalizing prospect of being much easier to produce.

'Invisible tattoos' could improve body confidence after breast cancer radiotherapy

Invisible tattoos could replace the permanent dark ink tattoos used to ensure that breast cancer patients having radiotherapy are treated in exactly the same spot during each session, according to results from a pilot study to be presented at the National Cancer Research Institute (NCRI) Cancer Conference today (Sunday)*.

Research suggests that the permanent pin prick marks made on the skin of women having radiotherapy reminds them of their diagnosis for years to come, reducing body confidence and self-esteem.

Step towards blood test for many cancer types

Scientists have identified more than 800 markers in the blood of cancer patients that could help lead to a single blood test for early detection of many types of cancer in future, according to research presented at the National Cancer Research Institute (NCRI) Cancer Conference in Liverpool today (Sunday).

JNS: Pediatrics publishes guidelines for the treatment of pediatric hydrocephalus

Charlottesville, VA (November 1, 2014). The Journal of Neurosurgery Publishing Group is pleased to announce today's publication of "Pediatric hydrocephalus: systematic literature review and evidence-based guidelines," a supplement to the November issue of the Journal of Neurosurgery: Pediatrics.

Cancer cell fingerprints in the blood may speed up childhood cancer diagnosis

Newly-identified cancer cell fingerprints in the blood could one day help doctors diagnose a range of children's cancers faster and more accurately, according to research* presented at the National Cancer Research Institute (NCRI) Cancer Conference next week.

The researchers, from the University of Cambridge and Addenbrooke's Hospital in Cambridge, found unique molecular fingerprints for 11 types of children's tumours,** which could be used to develop blood tests to diagnose these cancers.

Scientists replicate the tide with two buckets, aquarium tubing, and a pump

Rachel MacTavish is growing salt marsh plants in microcosms that replicate the tide. She assembled them in an outdoor greenhouse at the Sapelo Island National Estuarine Research Reserve in Georgia, USA, with buckets from a hardware store, aquarium tubing, and pumps. Her tidal simulation units could be an important tool for preserving and restoring environmentally important wetlands, because they enable researchers to investigate tidal marsh plant growth in a controlled setting.

Are my muscular dystrophy drugs working?

INDIANAPOLIS -- People with muscular dystrophy could one day assess the effectiveness of their medication with the help of a smartphone-linked device, a new study in mice suggests. The study used a new method to process ultrasound imaging information that could lead to hand-held instruments that provide fast, convenient medical information.