Body

Older women with disordered breathing during sleep were found to be at greater risk of decline in the ability to perform daily activities, such as grocery shopping and meal preparation, according to a new study led by researchers at the Johns Hopkins Bloomberg School of Public Health and the University of California, San Francisco.

The study was published Nov. 6 in the online edition of the Journal of the American Geriatrics Society.

(MEMPHIS, Tenn. - November 12, 2014) An international collaboration has identified frequent mutations in two genes that often occur together in Ewing sarcoma (EWS) and that define a subtype of the cancer associated with reduced survival. The research, conducted by the St. Jude Children's Research Hospital-Washington University Pediatric Cancer Genome Project and the Institut Curie-Inserm through the International Cancer Genome Consortium, appears in the current issue of the scientific journal Cancer Discovery.

Giant otters may have a vocal repertoire with 22 distinct vocalization types produced by adults and 11 neonate vocalization types, according to a study published November 12, 2014 in the open-access journal PLOS ONE by Christina Mumm and Mirjam Knörnschild from University of Ulm, Germany.

Using fewer than twenty genomes, researchers were unable to find rare protein-altering variants significantly associated with extreme longevity, according to a study published November 12, 2014 in the open-access journal PLOS ONE by Hinco Gierman from Stanford University and colleagues.

In the fight against HIV, microbicides--chemical compounds that can be applied topically to the female genital tract to protect against sexually transmitted infections--have been touted as an effective alternative to condoms. However, while these compounds are successful at preventing transmission of the virus in a petri dish, clinical trials using microbicides have largely failed. A new study from the Gladstone Institutes and the University of Ulm now reveals that this discrepancy may be due to the primary mode of transportation of the virus during sexual transmission, semen.

New York, NY - The female mosquitoes that spread dengue and yellow fever didn't always rely on human blood to nourish their eggs. Their ancestors fed on furrier animals in the forest. But then, thousands of years ago, some of these bloodsuckers made a smart switch: They began biting humans and hitchhiked all over the globe, spreading disease in their wake.

As cities and incomes increase around the world, so does consumption of refined sugars, refined fats, oils and resource- and land-intense agricultural products such as beef. A new study led by University of Minnesota ecologist David Tilman shows how a shift away from this trajectory and toward healthier traditional Mediterranean, pescatarian or vegetarian diets could not only boost human lifespan and quality of life, but also slash greenhouse gas emissions and save habitat for endangered species.

A research team led by Jackson Laboratory Professors Frank McKeon, Ph.D., and Wa Xian, Ph.D., reports on the role of certain lung stem cells in regenerating lungs damaged by disease.

The work, published Nov. 12 in the journal Nature, sheds light on the inner workings of the still-emerging concept of lung regeneration and points to potential therapeutic strategies that harness these lung stem cells.

HANOVER, N.H. - China's anti-logging, conservation and ecotourism policies are accelerating the loss of old-growth forests in one of the world's most ecologically fragile places, according to studies led by a Dartmouth College scientist.

The human immunodeficiency virus (HIV) can insert itself at different locations in the DNA of its human host - and this specific integration site determines how quickly the disease progresses, report researchers at KU Leuven's Laboratory for Molecular Virology and Gene Therapy. The study was published online today in the journal Cell Host & Microbe.

When HIV enters the bloodstream, virus particles bind to and invade human immune cells. HIV then reprogrammes the hijacked cell to make new HIV particles.

Providing health information on the internet may not be the "cure all" that it is hoped to be. It could sideline especially those Americans older than 65 years old who are not well versed in understanding health matters, and who do not use the web regularly. So says Helen Levy of the University of Michigan in the US, who led the first-ever study to show that elderly people's knowledge of health matters, so-called health literacy, also predicts how and if they use the internet. The findings¹ appear in the Journal of General Internal Medicine², published by Springer.

The tree has been an effective model of evolution for 150 years, but a Rice University computer scientist believes it's far too simple to illustrate the breadth of current knowledge.

Shark populations in the Mediterranean are highly divided, an international team of scientists, led by Dr Andrew Griffiths of the University of Bristol, has shown. Many previous studies on sharks suggest they move over large distances. But catsharks in the Mediterranean Sea appear to move and migrate much less, as revealed by this study. This could have important implications for conserving and managing sharks more widely, suggesting they may be more vulnerable to over-fishing than previously thought.

COLUMBIA, MO. - Sugar-sweetened beverages are the largest source of added sugar in the diets of adolescents in the United States, and young adults ages 15-20 consume more of these drinks than any other age group, according to the Centers for Disease Control and Prevention. Adolescent obesity rates, which have quadrupled over the past thirty years, led to widespread scrutiny of added dietary sugars, especially those found in carbonated beverages.

In an unexpected mashup of financial and mechanical engineering, researchers have discovered that the same modeling used to forecast fluctuations in the stock market can be used to predict aspects of animal behavior. Their work proposes an unprecedented model for in silico--or computer-based--simulations of animal behavior. The findings were published in the Journal of the Royal Society Interface.