Body

Pygmy phenotype developed many times, adaptive to rainforest

The small body size associated with the pygmy phenotype is probably a selective adaptation for rainforest hunter-gatherers, according to an international team of researchers, but all African pygmy phenotypes do not have the same genetic underpinning, suggesting a more recent adaptation than previously thought.

Proteins critical to wound healing identified

Mice missing two important proteins of the vascular system develop normally and appear healthy in adulthood, as long as they don't become injured. If they do, their wounds don't heal properly, a new study shows.

The research, at Washington University School of Medicine in St. Louis, may have implications for treating diseases involving abnormal blood vessel growth, such as the impaired wound healing often seen in diabetes and the loss of vision caused by macular degeneration.

Why aren't pregnant women getting flu vaccine?

Both mother and fetus are at increased risk for complications of flu infection during pregnancy. And prenatal care providers say they're advising women to get the flu vaccine, in line with recommendations from various organizations. But many pregnant women don't understand the importance of this advice—and don't get the vaccine.

Massachussetts General-developed device monitors key step in development of tumor metastases

A microfluidic device developed at Massachusetts General Hospital (MGH) may help study key steps in the process by which cancer cells break off from a primary tumor to invade other tissues and form metastases. In their report published in Nature Materials, the investigators describe an stands for epithelial-mesenchymal transition, a fundamental change in cellular characteristics that has been associated with the ability of tumor cells to migrate and invade other sites in the body. Therapies that target this process may be able to slow or halt tumor metastasis.

Passport study reveals vulnerability in photo-ID security checks

Security systems based on photo identification could be significantly improved by selecting staff who have an aptitude for this very difficult visual task, a study of Australian passport officers suggests.

Previous research has shown that people find it challenging to match unfamiliar faces.

"Despite this, photo-ID is still widely used in security settings. Whenever we cross a border, apply for a passport or access secure premises, our appearance is checked against a photograph," says UNSW psychologist Dr David White.

Older coral species more hardy, UT Arlington biologists say

New research indicates older species of coral have more of what it takes to survive a warming and increasingly polluted climate, according to biologists from the University of Texas at Arlington and the University of Puerto Rico – Mayagüez.

The researchers examined 140 samples of 14 species of Caribbean corals for a study published by the open-access journal PLOS ONE on Aug. 18.

More than just X and Y: a new genetic basis for sex determination

Cold Spring Harbor, NY – Men and women differ in plenty of obvious ways, and scientists have long known that genetic differences buried deep within our DNA underlie these distinctions. In the past, most research has focused on understanding how the genes that encode proteins act as sex determinants. But Cold Spring Harbor Laboratory (CSHL) scientists have found that a subset of very small genes encoding short RNA molecules, called microRNAs (miRNAs), also play a key role in differentiating male and female tissues in the fruit fly.

Resistant hypertension: A review for physicians

A new review article on resistant hypertension, which affects about 1 in 10 people with high blood pressure, is aimed at helping physicians assess and manage patients with the condition. The review, published in CMAJ (Canadian Medical Association Journal) includes information on emerging therapies for the condition.

Engineering long-lasting joint lubrication by mimicking nature

By finding a way to bind a slippery molecule naturally found in the fluid that surrounds healthy joints, Johns Hopkins researchers have engineered surfaces that have the potential to deliver long-lasting lubrication at specific spots throughout the body. The finding, described in the Aug. 3 online edition of Nature Materials, could eventually offer a new way to ease the pain of arthritic joints, keep artificial joints working smoothly or even make contact lenses more comfortable.

Applying new cholesterol guidelines to a patient population reduces heart attacks, strokes, study finds

DALLAS – August 18, 2014 – A study from UT Southwestern researchers found that recently introduced cholesterol guidelines would significantly reduce new cardiovascular events, when compared to treatment based on previous cholesterol guidelines.

The research identified Dallas Heart Study participants in the 30 to 65 age range who would have newly qualified for statin use under the new cholesterol guidelines introduced in 2013 by the American College of Cardiology (ACC) and the American Heart Association (AHA).

New mouse model points to therapy for liver disease

Non-alcoholic fatty liver disease (NAFLD) is a common affliction, affecting almost 30 percent of Americans, with a significant number suffering from its most severe form, called non-alcoholic steatohepatitis or NASH, which can lead to cirrhosis and liver cancer. In recent years, NASH has become the leading cause of liver transplantation.

Blood pressure medication does not cause more falls

It's time to question the common belief that patients receiving intensive blood pressure treatment are prone to falling and breaking bones. A comprehensive study in people ages 40 to 79 with diabetes, led by Karen Margolis, MD, of HealthPartners Institute for Education and Research in the US, found no evidence supporting this belief. The study¹ appears in the Journal of General Internal Medicine², published by Springer.

Study: World's primary forests on the brink

August 18, 2014: An international team of conservationist scientists and practitioners has published new research showing the precarious state of the world's primary forests.

The global analysis and map are featured in a paper appearing in the esteemed journal Conservation Letters and reveals that only five percent of the world's pre-agricultural primary forest cover is now found in protected areas.

A new species of endemic treefrog from Madagascar

A new species of the Boophis rappiodes group is described from the hidden streams of Ankarafa Forest, northwest of Madagascar. The study was published in the open access journal ZooKeys.

The new species Boophis ankarafensis is green in colour with bright red speckling across its head and back, but what truly distinguishes this species is a high genetic divergence and different call with a triple click, compared to the usual double.

500 million year reset for the immune system

This news release is available in German.