Body

Key to universal flu vaccine: Embrace the unfamiliar

Vaccine researchers have developed a strategy aimed at generating broadly cross-reactive antibodies against the influenza virus: embrace the unfamiliar.

In recent years, researchers interested in a "universal flu vaccine" identified a region of the viral hemagglutinin protein called the stem or stalk, which doesn't mutate and change as much as other regions and could be the basis for a vaccine that is protective against a variety of flu strains.

Black carbon -- a major climate pollutant -- also linked to cardiovascular health

Black carbon pollutants from wood smoke are known to trap heat near the earth's surface and warm the climate. A new study led by McGill Professor Jill Baumgartner suggests that black carbon may also increase women's risk of cardiovascular disease.

To investigate the effects of black carbon pollutants on the health of women cooking with traditional wood stoves, Baumgartner, a researcher at McGill's Institute for the Health and Social Policy, measured the daily exposure to different types of air pollutants, including black carbon, in 280 women in China's rural Yunnan province.

Tilted acoustic tweezers separate cells gently

Precise, gentle and efficient cell separation from a device the size of a cell phone may be possible thanks to tilt-angle standing surface acoustic waves, according to a team of engineers.

"For biological testing we often need to do cell separation before analysis," said Tony Jun Huang, professor of engineering science and mechanics. "But if the separation process affects the integrity of the cells, damages them in any way, the diagnosis often won't work well."

Sweet! Glycoconjugates are more than the sum of their sugars

There's a certain type of biomolecule built like a nano-Christmas tree. Called a glycoconjugate, it's many branches are bedecked with sugary ornaments.

It's those ornaments that get all the glory. That's because, according to conventional wisdom, the glycoconjugate's lowly "tree" basically holds the sugars in place as they do the important work of reacting with other molecules.

Now a chemist at Michigan Technological University has discovered that the tree itself—called the scaffold—is a good deal more than a simple prop.

Doctors miss opportunities to offer flu shots

Doctors should make a point of offering a flu vaccine to their patients. A simple reminder could considerably reduce the number of racial and ethnic minorities who currently do not vaccinate themselves against this common contagious respiratory illness. This recommendation is based on research led by Jürgen Maurer of the University of Lausanne in Switzerland and the RAND Corporation in the US. Their findings¹ are published in the Journal of General Internal Medicine², published by Springer.

Sweet! Glycocongugates are more than the sum of their sugars

There's a certain type of biomolecule built like a nano-Christmas tree. Called a glycoconjugate, it's many branches are bedecked with sugary ornaments.

It's those ornaments that get all the glory. That's because, according to conventional wisdom, the glycoconjugate's lowly "tree" basically holds the sugars in place as they do the important work of reacting with other molecules.

Now a chemist at Michigan Technological University has discovered that the tree itself—called the scaffold—is a good deal more than a simple prop.

Racial and ethnic stereotypes may contribute to obesity among minorities

Many Americans need extraordinary willpower to avoid becoming obese – or to slim down if they already weigh too much. For members of minority groups, maintaining a healthy weight can be that much harder according to new research led by Luis Rivera, an experimental social psychologist at Rutgers University-Newark.

Rivera says it is common for minorities in the United States to endure negative stereotypes, pervasive messages that suggest those groups are inferior, and that these attitudes can prevent people from doing what is needed to care for their health.

Knee surgery shows no benefit for people with mild osteoarthritis

A new study indicates that there is no apparent benefit to arthroscopic knee surgery for age-related tears of the meniscus in comparison with nonsurgical or sham treatments. The study, published in CMAJ (Canadian Medical Association Journal), provides evidence that middle-aged or older patients with mild or no osteoarthritis of the knee may not benefit from the procedure.

Knee surgery not needed for mild osteoarthritis: Study

Their study, published in the Canadian Medical Association Journal (CMAJ) today, says middle-aged or older patients with mild or no osteoarthritis of the knee may not benefit from the procedure of arthroscopic knee surgery. Each year more than four million such keyhole surgeries are performed worldwide for degenerative meniscus tears.

INFORMS study shows social welfare may fall in a more ethical market

For "credence services" such as auto-repair, healthcare, and legal services, the benefit to the customers for the service is difficult to assess before and even after the service. A new study in a journal of the Institute for Operations Research and the Management Sciences (INFORMS) finds that in a credence services market, when more service providers care about the customer's well-being, society as whole may actually be worse off.

Illinois scientists work with World Health Organization to fortify condiments, seasonings

URBANA, Ill. – Two University of Illinois scientists are contributing to World Health Organization (WHO) efforts to fortify condiments and seasonings for use in countries with widespread micronutrient deficiencies.

Study shows promise in automated reasoning, hypothesis generation over complete medical literature

HOUSTON – (Aug. 25, 2014) – With approximately 50 million scientific papers available in public databases– and a new one publishing nearly every 30 seconds – scientists cannot know about every relevant study when they are deciding where to take their research next.

A new tool in development by computational biologists at Baylor College of Medicine and analytics experts at IBM research and tested as a "proof-of-principle" may one day help researchers mine all public medical literature and formulate hypotheses that promise the greatest reward when pursuing new scientific studies.

UNC Lineberger researchers develop new approach to identify 'drivers' of cancer

CHAPEL HILL, NC – UNC Lineberger Comprehensive Cancer Center researchers have developed a new integrated approach to pinpoint the genetic "drivers" of cancer, uncovering eight genes that could be viable for targeted breast cancer therapy.

Nursing home care improves with culture change

PROVIDENCE, R.I. [Brown University] — If a nursing home makes an extensive investment in "culture change" it will see improvements in quality of care, according to a new study led by Brown University gerontology researchers.

Core mechanism for root growth identified

During plant growth, dividing cells in meristems must coordinate transitions from division to expansion and differentiation. Three distinct developmental zones are generated: the meristem, where the cell division takes place, and elongation and differentiation zones. At the same time, plants can rapidly adjust their direction of growth to adapt to environmental conditions.