Body

Ottawa, Canada (September 17, 2012) –A new study published today in the journal Applied Physiology, Nutrition, and Metabolism (APNM) looks beyond the much-feared weight gain common to first-year students and reports on the full 4-year impact of higher education on weight, BMI, and body composition.

Tafamidis meglumine (trade name: Vyndaqel®) was approved in November 2011 for the treatment of transthyretin amyloidosis in adults. This rare disorder ("orphan disease") is caused by a defective gene and is associated with progressive nerve damage (neurological degeneration) that tafamidis is supposed to delay. According to § 35a SGB (Social Code Book) V, an added benefit is regarded as proven if a drug for a rare disease - known as an orphan drug - has been approved.

A team of Cardiff University scientists is leading new research to develop a vaccine against anthrax to help counteract the threat of bioterrorism.

Working with scientists from the Republic of Georgia, Turkey and the USA, Professor Les Baillie from Cardiff University's School of Pharmacy and Pharmaceutical Sciences is leading a NATO project to tackle the potential misuse of anthrax.

The clot-inhibiting drug apixaban (trade name: Eliquis®) was approved in May 2011 for the prevention of thrombosis (blood clots) after operations to replace a hip or knee joint. In an early benefit assessment pursuant to the "Act on the Reform of the Market for Medicinal Products" (AMNOG), the German Institute for Quality and Efficiency in Health Care (IQWiG) examined the added benefit of apixaban.

Los Angeles, (17 September 2012). Kids who get migraine headaches are much more likely than other children to also have behavioral difficulties, including social and attention issues, and anxiety and depression. The more frequent the headaches, the greater the effect, according to research out now in the journal Cephalagia, published by SAGE.

Bethesda, MD — If you are overweight and pregnant, your baby isn't destined to a life of obesity after all, according to a new research report published online in The FASEB Journal. In the report, a team of U.S. scientists show that modifying fat intake during pregnancy to a moderate level is enough to benefit the child regardless of the mother's size.

An international collaboration led by Tom Battin from the Department of Limnology of the University of Vienna unravels the role of Alpine glaciers for carbon cycling. The scientists uncover the unexpected biogeochemical complexity of dissolved organic matter locked in glaciers and study its fate for carbon cycling in glacier-fed streams. Their paper, now published in Nature Geoscience, expands current knowledge on the importance of the vanishing cryosphere for biogeochemistry.

ATLANTA –September 17, 2012– A new report from American Cancer Society researchers finds that despite declining death rates, cancer has surpassed heart disease as the leading cause of death among Hispanics in the U.S. In 2009, the most recent year for which actual data are available, 29,935 people of Hispanic origin in the U.S. died of cancer, compared to 29,611 deaths from heart disease. Among non-Hispanic whites and African Americans, heart disease remains the number one cause of death.

There is no scientific evidence that low-level electromagnetic field exposure from mobile phones and other transmitting devices causes adverse health effects, according to a report presented by a Norwegian Expert Committee. In addition, the Committee provides advice to authorities about risk management and regulatory practice.

HOUSTON – A new study published online in Nature Medicine, led by scientists at The University of Texas MD Anderson Cancer Center, describes the discovery of a novel drug combination aimed at a subset of melanoma patients who currently have no effective therapeutic options.

Melanoma patients have different responses to therapy, depending on what genes are mutated in their tumors. About half of melanomas have a mutation in the BRAF gene; while a quarter have a mutation in the NRAS gene.

A PhD student at the University of Copenhagen has drawn on nature's own pharmacy to help improve the treatment of snakebites in Africa.

Marianne Molander from the University of Copenhagen's Faculty of Health and Medical Sciences has been working within a Danish team that has examined various plants native to the African continent in a bid to find locally available herbal antidotes.

Co-streams from the food industry are excellent sources of proteins and healthy oils for use in foods and cosmetics. However, at the moment these side streams are mainly used as fish and animal feed, for energy, or end up as waste.

The first detailed and complete picture of a protein complex that is tied to human birth defects as well as the progression of many forms of cancer has been obtained by an international team of researchers led by scientists with the U.S. Department of Energy (DOE)'s Lawrence Berkeley National Laboratory (Berkeley Lab). Knowing the architecture of this protein, PRC2, for Polycomb Repressive Complex 2, should be a boon to its future use in the development of new and improved therapeutic drugs.

The rare disorder Wolfram syndrome is caused by mutations in a single gene, but its effects on the body are far reaching. The disease leads to diabetes, hearing and vision loss, nerve cell damage that causes motor difficulties, and early death.

HEIDELBERG, 17 September 2012 – A natural product secreted by a soil bacterium shows promise as a new drug to treat tuberculosis report scientists in a new study published in EMBO Molecular Medicine. A team of scientists working in Switzerland has shown how pyridomycin, a natural antibiotic produced by the bacterium Dactylosporangium fulvum, works. This promising drug candidate is active against many of the drug-resistant types of the tuberculosis bacterium that no longer respond to treatment with the front-line drug isoniazid.