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In low-and-middle income countries, pregnancy-related infections are a major cause of maternal death, can also be fatal to unborn and newborn babies, and are mostly caused by four types of conditions that are treatable and preventable, according to a review by US researchers published in this week's PLOS Medicine.

(Boston) – Researchers at Boston Medical Center (BMC) have shown that patient navigation services help decrease the time to diagnosis for female patients who have received an abnormal result from a breast or cervical cancer screening. The study demonstrates the importance of patient navigation in helping vulnerable populations get the care that they need in a timely manner and supports the recent standard recommendations for all cancer care centers to provide patient navigation services.

CHICAGO – In children and adolescents with hemophilia, vigorous physical activity was associated with an elevated risk of bleeding, although it appears the absolute increase in risk may be small, according to a study in the October 10 issue of JAMA.

CHICAGO – Plasma levels of proneurotensin are associated with the development of diabetes, cardiovascular disease, cardiovascular and total mortality, and breast cancer in women during long-term follow-up, according to a study in the October 10 issue of JAMA.

PITTSBURGH, Oct. 9, 2012 – Medicare beneficiaries are overpaying by hundreds of dollars annually because of difficulties selecting the ideal prescription drug plan for their medical needs, an investigation by University of Pittsburgh Graduate School of Public Health researchers reveals.

PITTSBURGH, Oct. 9, 2012 – An individual hospital's infection control efforts have a ripple effect on the prevalence of a deadly and highly infectious bacterium in hospitals throughout its surrounding region, a multi-center research group led by the University of Pittsburgh demonstrated in a computer simulation-based study.

Comparative effectiveness research conducted over the past decade has had a limited impact on the way medical care is delivered, but many opportunities exist to help doctors and others in the medical system translate such research into better patient care, according to a new RAND Corporation study.

JUPITER, FL, October 9, 2012 – Scientists from the Florida campus of The Scripps Research Institute (TSRI) have developed a new method of screening more than three million combinations of interactions between RNA and small molecules to identify the best targets on RNA as well as the most promising potential drug compounds. This novel technology may lead to more efficient drug development.

The study was published in the October 9, 2012 issue of the journal Nature Communications.

The world's leading mass spectrometer manufacturers have agreed to license technology that enabled University of Southern California (USC) researchers to develop software that, for the first time, allows scientists to easily use and share research data collected across proprietary platforms.

The ProteoWizard Toolkit, a cross-platform set of libraries and applications designed to facilitate the sharing of raw data and its analysis, is expected to bolster large-scale biological research and help improve the understanding of complex diseases like cancer.

New York, NY (October 8, 2012) — Columbia University Medical Center (CUMC) researchers have found that a diet high in saturated fat raises levels of endothelial lipase (EL), an enzyme associated with the development of atherosclerosis, and, conversely, that a diet high in omega-3 polyunsaturated fat lowers levels of this enzyme. The findings establish a "new" link between diet and atherosclerosis and suggest a novel way to prevent cardiovascular heart disease.

This press release is available in Spanish.

Two to three millimeters long, the parasitoid wasp Habrobracon hebetor is a top candidate for use in programs to biologically control Indianmeal moths and other stored-product pests. But despite the prospects for reduced insecticide use and product losses, the approach has yet to gain traction commercially, in part because of the lack of an efficient method of stockpiling the wasp.

But a team of scientists, including researchers from the U.S. Department of Agriculture (USDA), is working on the problem.

Some animal models developed by researchers at the Institute of Biomedical Research of Bellvitge (IDIBELL) and the Catalan Institute of Oncology (ICO) has served to validate the effectiveness of a new drug against ovarian cancer resistant to cisplatin. The multidisciplinary work, done in collaboration with the biopharmaceutical company Pharmamar, was published in the journal Clinical Cancer Research.

Hospital readmission rates and early death rates are used to rank hospital performance but there can be significant variation in their values, depending on how they are calculated, according to a new study in CMAJ (Canadian Medical Association Journal).

CAMBRIDGE, MA -- Although tumor metastasis causes about 90 percent of cancer deaths, the exact mechanism that allows cancer cells to spread from one part of the body to another is not well understood. One key question is how tumor cells detach from the structural elements that normally hold tissues in place, then reattach themselves in a new site.

Among the most popular questions addressed in online communication research is the extent to which Internet use leads to undesirable psychosocial outcomes such as depression and loneliness. Evidence suggests that certain motivations to communicate online can have negative consequences, as the Internet itself can, for some, serve as an object of compulsive use.