Body

PHILADELPHIA— Restoring diminished levels of a protein shown to prevent and reverse heart failure damage could also have therapeutic applications for patients with critical limb ischemia (CLI), suggests a new preclinical study published online October 9 in Circulation Research from researchers at the Center for Translational Medicine at Thomas Jefferson University .

Philadelphia, PA, October 10, 2012 – A new study reinforces the finding that a region of the genome involved in immune system function, called the major histocompatibility complex (MHC), is involved in the genetic susceptibility to schizophrenia.

Schizophrenia is among the most disabling psychiatric disorders. Approximately 80% of the risk for developing schizophrenia is heritable, but there has been slow progress in identifying genetic variation that contributes to the risk for schizophrenia.

Do you have it in mind to go to a mountain top and study beetles that nobody else has ever seen? Well, there are two fewer such mountains available now that beetle species discovered on Mont Tohiea and Mont Mauru in the Society Islands have been named. James Liebherr, Curator of the Cornell University Insect Collection, has just described 14 species of predatory carabid beetle, also called ground beetles, as part of a U.S.

UPTON, NY-Scientists at the U.S. Department of Energy's (DOE) Brookhaven National Laboratory, with collaborators from Harvard University, the University of Madrid, Princeton University, and the University of Zurich, have discovered a new mechanism that may alter principle understandings of molecular interactions within a cell's nucleus. The discovery illustrates how two proteins of the human adenovirus use DNA as an efficient form of transportation inside a newly synthesized virus particle.

The findings have been presented in a study from Lund University in Sweden, published in the Journal of the American Medical Association.

"It was surprising to find such a clear link to the risk of type 2 diabetes and cardiovascular disease as well as to breast cancer. Obesity is a common risk factor for all three conditions, but the connection with neurotensin is not explained by obesity or other known risk factors", says Professor Olle Melander from the Department of Clinical Sciences at Lund University, who is also a consultant at Skåne University Hospital.

The speed and degree to which the pupil of the eye responds is a standard test for alertness. It has also been used to assess how sleepy or exhausted a person is. Now, research to be published in the International Journal of Bioinformatics Research and Applications suggests that measuring pupil response alone is not enough and that a person's rate of blinking should also be incorporated to obtain a more precise measure of alertness. The work could be important in the care of people with multiple sclerosis and other conditions.

There have been claims recently that the HPV (Human papillomavirus) vaccination increases sexual activity in adolescent girls as it effectively gives them a 'green light' to have sex because of a perceived protection against sexually transmitted infections. This study published in Vaccine, examines whether or not there is any influence on sexual behaviour as a result of being offered or given the vaccination.

In low-and-middle income countries, pregnancy-related infections are a major cause of maternal death, can also be fatal to unborn and newborn babies, and are mostly caused by four types of conditions that are treatable and preventable, according to a review by US researchers published in this week's PLOS Medicine.

University of Guam Marine Lab scientist, Tom Shils and coauthor Heroen Verbruggen of the University of Melbourne have recently published an article describing a new species of algae found in the waters of Guam. Rhipilia coppejansii is the fifth green alga described from the Mariana Islands and the first one since 1978.

The speed and degree to which the pupil of the eye responds is a standard test for alertness. It has also been used to assess how sleepy or exhausted a person is. Now, research to be published in the International Journal of Bioinformatics Research and Applications suggests that measuring pupil response alone is not enough and that a person's rate of blinking should also be incorporated to obtain a more precise measure of alertness. The work could be important in the care of people with multiple sclerosis and other conditions.

Los Angeles, CA (October 9, 2012) - In the new fall issue of the World Policy Journal, the editors liken today's period of politics to an "electoral tsunami." With more of the world's population heading to the polls than ever before, this new issue of WPJ includes a collection of articles that take an in-depth look at democracy: the opportunities it presents, and the dangers that put it at risk.

Women who have undergone female genital mutilation (FGM) have a significantly lower sexual quality of life finds a new study published today (10 October) in BJOG: An International Journal of Obstetrics and Gynaecology.

FGM is defined as any procedure 'involving partial or total removal of the external female genitalia without medical reasons'.

HRT therapy has been subject to much discussion due to both positive effects (reduced risk of cardiovascular disease) and negative effects (increased risk of breast cancer). A paper published in the BMJ Group's Journal of Family Planning and Reproductive Healthcare back in January cast doubt on the "unreliable" Million Women Study which associated HRT with an increased risk of breast cancer.

Professor Alfirevic from the Department of Women's and Children's Health at the University of Liverpool argues that although premature children tend to have lower cognitive ability than their peers and 14.9 million are born prematurely each year worldwide, is it really possible to stop spontaneous preterm labour?

In this week's PLOS Medicine, Anna Borquez from Imperial College London and an international group of authors developed a mathematical model representing the HIV epidemic among men who have sex with men (MSM) and transwomen in Lima, Peru as a test-case for the effectiveness of HIV pre-exposure prophylaxis (PrEP). The model was used to investigate the population-level impact, cost, and cost-effectiveness of PrEP under a range of different scenarios.