Researchers have found that the bacteria are able to change key cells that line the intestine, enabling the bugs to thrive.
By changing the make-up of these cells, the salmonella bacteria are able to cross the gut wall and infect vital organs, such as the kidneys and the liver.
Salmonella food poisoning – commonly caused by eating undercooked poultry or eggs – can lead to diarrhoea, fever and even death in young children.
Scientists say the study furthers our understanding of how bacterial infections occur and what enables them to spread.