Body

Vaccination reduces the risk of unvaccinated badger cubs testing tuberculosis positive

New evidence from a four-year field study has shown that BCG vaccination reduces the risk of tuberculosis infection in unvaccinated badger cubs in vaccinated groups, as well as in badgers that received the vaccine.

Ceramic indoor cookstove use did not significantly lower child pneumonia risk in rural Kenya

DEERFIELD, Il. (December 11, 2012)—Inexpensive, locally-produced ceramic cookstoves may produce less smoke than traditional indoor 3-stone firepits, but they don't significantly reduce indoor air pollution or the risk of pneumonia in young children, according to results from a small, year-long observational study by researchers working in rural Kenya.

Building better barley

As one of the top 10 barley producers in the world, Canada faces a problem of adapting to the 'new normal' of a warmer, drier climate.

The 2012 growing season was considered an average year on the Canadian Prairies, "but we still had a summer water deficit, and it is that type of condition we are trying to work with," said Scott Chang, a professor of soil science in the University of Alberta's Department of Renewable Resources in Edmonton, Canada.

Protein strongest just before death

Researchers at Michigan State University have discovered a protein that does its best work with one foot in the grave.

The study, which appears in the current issue of the Journal of Biological Chemistry, focuses on the nontraditional lifestyle of Retinoblastoma tumor suppressor proteins, which could lead to new ways to treat cancer.

Notre Dame research may have important implications for combating diabetes

Research by University of Notre Dame biochemist Anthony S. Serianni is providing new insights that could have important implications for understanding and treating diabetes.

Serianni points out that biological compounds known as dicarbonyl sugars are produced inside the human body from the natural breakdown of the simple sugar, glucose. The formation of these sugars is enhanced in diabetic patients because glucose concentrations in the blood and plasma of diabetics are significantly elevated.

UCLA scientists find drug that may help fight Duchenne muscular dystrophy

Drugs are currently being tested that show promise in treating patients with Duchenne muscular dystrophy (DMD), an inherited disease that affects about one in 3,600 boys and results in muscle degeneration and, eventually, death.

Delaying childbirth may reduce risk of an aggressive form of breast cancer

SEATTLE – Younger women who wait at least 15 years after their first menstrual period to give birth to their first child may reduce their risk of an aggressive form of breast cancer by up to 60 percent, according to a Fred Hutchinson Cancer Research Center study. The findings, by Christopher I. Li, M.D., Ph.D., a member of the Public Health Sciences Division at Fred Hutch, are published online in Breast Cancer Research and Treatment.

Patients with family history of colorectal cancer may be at risk for aggressive form of the disease

BOSTON--When people with a family history of colorectal cancer develop the disease, their tumors often carry a molecular sign that the cancer could be life-threatening and may require aggressive treatment, Dana-Farber Cancer Institute scientists report in a new study.

Chemical analysis reveals first cheese making in Northern Europe in the 6th millennium BC

The first unequivocal evidence that humans in prehistoric Northern Europe made cheese more than 7,000 years ago is described in research by an international team of scientists, led by the University of Bristol, UK, published today in Nature.

Fragile X protein linked to nearly 100 genes involved in autism

DURHAM, N.C. – Doctors have known for many years that patients with fragile X syndrome, the most common form of inherited intellectual disability, are often also diagnosed with autism. But little has been known about how the two diagnoses are related.

Study paves way to design drugs aimed at multiple protein targets at once

CHAPEL HILL, N.C. – An international research collaboration led by scientists at the University of North Carolina School of Medicine and the University of Dundee, in the U.K., have developed a way to efficiently and effectively make designer drugs that hit multiple protein targets at once.

This accomplishment, described in the Dec. 13, 2012 issue of the journal Nature, may prove invaluable for developing drugs to treat many common human diseases such as diabetes, high blood pressure, obesity, cancer, schizophrenia, and bi-polar disorder.

Relocating elephants fails to decrease human-wildlife conflict

Human–elephant conflict in Sri Lanka kills more than 70 humans and 200 Asian elephants every year. One of the most common tools in combating these conflicts is moving the elephants into ranges away from humans, often into national parks. This is done in hopes of avoiding problems that include elephants raiding crops, breaking into homes and injuring or killing people.

Cane toads can be stopped

It may be possible to stop the spread of can toads into new areas of Australia according to new research published today in the Journal of Applied Ecology.

One of the lead authors of the study, James Cook University's Dr Ben Phillips, said that their work, which involved an international team of scientists, showed that artificial waterbodies installed by graziers acted as critical stepping-stones for the toad invasion.

"By removing these waterbodies in key locations it is possible to halt the spread of toads," he said.

Emerging virus in raccoons may provide cancer clues

Rare brain tumors emerging among raccoons in Northern California and Oregon may be linked to a previously unidentified virus discovered by a team of researchers, led by scientists from the University of California, Davis. Their findings, published today in the journal Emerging Infectious Diseases, could lead to a better understanding of how viruses can cause cancer in animals and humans.

A second ascent of chemistry's Mt. Everest

In science's equivalent of ascending Mt. Everest, researchers are reporting success in one of the most difficult challenges in synthetic chemistry — a field in which scientists reproduce natural and other substances from jars of chemicals in a lab. The feat, reported in the Journal of the American Chemical Society, involved synthesis of a rare substance with promising in vitro anti-cancer effects found naturally in tiny amounts in a Chinese medicinal herb.