Body

ST. LOUIS -- In research published in the Jan. 17 issue of The Journal of Cell Biology, a team led by Susana Gonzalo, Ph.D., assistant professor of biochemistry and molecular biology at Saint Louis University, has discovered a molecular pathway that contributes to triple-negative breast cancer, an often deadly and treatment resistant form of cancer that tends to strike younger women.

NEW YORK - January 22, 2013 - In 2009, the Securities and Exchange Commission mandated that public companies submit portions of annual (10-K) and quarterly (10-Q) reports—in a digitized format known as eXtensible Business Reporting Language (XBRL). The goal of this type of data was to provide more relevant, timely, and reliable "interactive" data to investors and analysts. The XBRL-formatted data is meant to allow users to manipulate and organize the financial information according to their own purposes faster, cheaper, and more easily than current alternatives.

Light-sensing cells in the eye rely on their outer segment to convert light into neural signals that allow us to see. But because of its unique cylindrical shape, the outer segment is prone to breakage, which can cause blindness in humans. A study published by Cell Press on January 22nd in the Biophysical Journal provides new insight into the mechanical properties that cause the outer segment to snap under pressure. The new experimental and theoretical findings help to explain the origin of severe eye diseases and could lead to new ways of preventing blindness.

CHAMPAIGN, Ill. — While working out the structure of a cell-killing protein produced by some strains of the bacterium Enterococcus faecalis, researchers stumbled on a bit of unusual biochemistry. They found that a single enzyme helps form distinctly different, three-dimensional ring structures in the protein, one of which had never been observed before.

Los Angeles, CA (January 22, 2013)- A new study finds that nearly half of older teenagers and young adults break up and get back together with previous dating partners and over half of this group have sex as part of the reconciliation process. This study was recently published in the Journal of Adolescent Research, a SAGE journal.

A drug developed at Linköping University in Sweden protects against the side effects of cancer treatments while strengthening the effects on the tumour. An international drug evaluation is now starting up on a larger group of patients.

Image sensors are at the core of every digital camera. Before a snapshot appears on the display, the sensors first convert the light from the lens to electrical signals. The image processor then uses these to create the final photo.

Public acceptance of climate change's reality may have been influenced by the rate at which words moved from scientific journals into the mainstream, according to anthropologist Michael O'Brien, dean of the College of Arts and Science at the University of Missouri. A recent study of word usage in popular literature by O'Brien and his colleagues documented how the usage of certain words related to climate change has risen and fallen over the past two centuries.

New Orleans, LA – Research led by Dr. Suresh Alahari, the Fred Brazda Professor of Biochemistry and Molecular Biology at LSU Health Sciences Center New Orleans and its Stanley S. Scott Cancer Center, details exactly how the Her2 cancer gene promotes the progression and spread of breast cancer cells. The inactivation of a tumor suppression gene called Nischarin is among the mechanisms identified. The findings provide a new therapeutic target to block the function of Her2. The research was published in Cancer Research, OnlineFirst on January 21, 2013.

Philadelphia, Pa. (January 22, 2013) – The most comprehensive review of new legal and regulatory issues affecting advanced nursing practice across the United States is now available in the "25th Annual Legislative Update," presented exclusively by The Nurse Practitioner: The American Journal of Primary Healthcare.

Researchers at Royal Holloway university have found that Brazilians and Chileans want the state to buy on social and environmental criteria, not just on price.

Based on this pioneering research, researchers from Royal Holloway have been invited to be the first academics to join the UN Environmental Programme's global Sustainable Public Procurement Initiative and attend its meeting in Paris this week.

ROCHESTER, Minn. -- Bathing a tiny newborn can be an exciting experience for parents, but it can also be intimidating. Newborns are small and vulnerable, slippery when wet, and the products marketed for their delicate skin can leave parents with abundant choices. As newborns are welcomed into the world, their skin needs to adapt to the new environmental changes around them. It's important for parents to understand proper bathing techniques and the appropriate skin care needed for their little one.

This time of year many people make resolutions to live a healthier lifestyle, exercise more, lose weight and eat better. For the adolescents who are extremely obese in this country, diet and exercise alone often are not enough to get their weight down. Some of those teens will require weight loss surgery to improve their overall health.

An international team of researchers including Svante Pääbo and Qiaomei Fu of the Max Planck Institute for Evolutionary Anthropology in Leipzig, Germany, sequenced nuclear and mitochondrial DNA that had been extracted from the leg of an early modern human from Tianyuan Cave near Beijing, China. Analyses of this individual's DNA showed that the Tianyuan human shared a common origin with the ancestors of many present-day Asians and Native Americans.

A collaborative research team including a Medical College of Wisconsin (MCW) pediatric neuropathologist successfully mitigated some of the effects of a muscular disease by using a new targeted enzyme replacement therapy strategy from 4s3 Bioscience.

The findings are published in the January edition of Human and Molecular Genetics http://hmg.oxfordjournals.org/content/early/2013/01/09/hmg.ddt003.full.pdf+html.