Body

Blood vessels 'sniff' gut microbes to regulate blood pressure

Researchers at The Johns Hopkins University and Yale University have discovered that a specialized receptor, normally found in the nose, is also in blood vessels throughout the body, sensing small molecules created by microbes that line mammalian intestines, and responding to these molecules by increasing blood pressure. The finding suggests that gut bacteria are an integral part of the body's complex system for maintaining a stable blood pressure.

Research suggests malaria can be defeated without a globally led eradication program

A researcher at the University of Southampton, working as part of a team from the UK and USA, believes the global eradication of malaria could be achieved by individual countries eliminating the disease within their own borders and coordinating efforts regionally. The team's findings have been published in the journal Science.

Cell discovery could hold key to causes of inherited diseases

Fresh insights into the protective seal that surrounds the DNA of our cells could help develop treatments for inherited muscle, brain, bone and skin disorders.

Researchers have discovered that the proteins within this coating – known as the nuclear envelope – vary greatly between cells in different organs of the body.

This variation means that certain disease causing proteins will interact with the proteins in the protective seal to cause illness in some organs, but not others.

Afterschool programs evaluated for community support, resources

UNIVERSITY PARK, Pa. -- Afterschool programs seem to be most effective when their organization and implementation is supported by both organizational and community resources, according to Penn State human development researchers.

Using a tool to help bridge the gap between research and real life, the researchers evaluated an afterschool program called the Good Behavior Game.

In probing mysteries of glass, researchers find a key to toughness

New Haven, Conn. — In a paper published online Feb. 26 in the journal Nature Communications, a Yale University team and collaborators propose a way of predicting whether a given glass will be brittle or ductile — a desirable property typically associated with metals like steel or aluminum — and assert that any glass could have either quality.

Ductility refers to a material's plasticity, or its ability to change shape without breaking.

Women's iron intake may help to protect against PMS

AMHERST, Mass. – Women who reported eating a diet rich in iron were 30 to 40 percent less likely to develop pre-menstrual syndrome (PMS) than women who consumed lower amounts, in a study reported this week by researchers at the University of Massachusetts Amherst School of Public Health and Health Sciences and Harvard. It is one of the first to evaluate whether dietary mineral intake is associated with PMS development.

Sweet news for stem cell's 'Holy Grail'

Scientists have used sugar-coated scaffolding to move a step closer to the routine use of stem cells in the clinic and unlock their huge potential to cure diseases from Alzheimer's to diabetes.

Stem cells have the unique ability to turn into any type of human cell, opening up all sorts of therapeutic possibilities for some of the world's incurable diseases and conditions.

The problem facing scientists is how to encourage stem cells to turn into the particular type of cell required to treat a specific disease.

2 new species of mushroom documented in the Iberian Peninsula

In collaboration with the Royal Botanic Gardens of Madrid and the Slovenian Forestry Institute, researchers in the Basque Country have documented two new species of Hydnum, commonly known as ox tongue mushrooms, as part of their study published in the 'Mycologia' journal. This genus is known because many of its fungi are edible.

Spanish researchers have headed the discovery of two mushroom species belonging to the Hydnum genus, a type of fungus commonly used in cooking.

EARTH: Setting sail on unknown seas

Alexandria, VA – On June 5, 2012, a massive dock made landfall on Oregon's Agate Beach, just north of Newport. The dock carried with it a host of castaways, including as many as a hundred species of mollusks, anemones, sponges, oysters, crabs, barnacles, worms, sea stars, mussels and sea urchins. A placard on the side written in Japanese revealed that the dock had been unmoored from the Japanese coastal city of Misawa during the catastrophic tsunami on March 11, 2011, bringing with it an essentially intact subtidal community of Asian species to the Pacific Northwest.

When morning sickness lasts all day

Almost all women experience some nausea or vomiting when pregnant. Approximately one out of every hundred suffers from acute nausea during pregnancy (hyperemesis gravidarum) and may need hospital treatment to restore hydration, electrolytes and vitamins intravenously.

"At worst, women may die if they go untreated. Many women find that the condition has an adverse effect on their work and family lives," states Åse Vikanes, senior researcher at the Norwegian Institute of Public Health and specialist in gynaecology and obstetrics.

Protecting health care workers

Health care workers who consistently wear special fitted face masks while on duty are much less likely to get clinical respiratory and bacterial infections, according to new research led by University of New South Wales (UNSW) academics.

The results, published in The American Journal of Critical Care Medicine, are particularly significant with the threat of possible pandemics and severe flu seasons, such as the current outbreak in the United States.

Fecal microbiota transplantation cures gastrointestinal diseases

(26 February 2013) Clostridium difficile infections have developed into a virtual pandemic over the past two decades. The outcome of standard antibiotic treatment is unsatisfactory: the recurrence rates are high with every relapse increasing the risk of further follow-ups. Faecal microbiota transplantation offers a rapidly acting and highly effective alternative in treating recurrent Clostridium difficile infections (RCDI), as Professor Lawrence J. Brandt (Montefiore Medical Center, New York, USA) points out.

An atlas of the human heart is drawn using statistics

Researchers at Pompeu Fabra University (Spain) have created a high resolution atlas of the heart with 3D images taken from 138 people. The study demonstrates that an average image of an organ along with its variations can be obtained for the purposes of comparing individual cases and differentiating healthy forms from pathologies.

"This atlas is a statistical description of how the heart and its components – such as the ventricles and the atrium – look," as explained to SINC by Corné Hoogendoorn, researcher at the CISTIB centre of the Pompeu Fabra University.

Researchers at the UH Cancer Center discover protein that may control the spread of cancer

HONOLULU, HI - Researchers at the University of Hawai'i Cancer Center have uncovered a novel mechanism that may lead to more selective ways to stop cancer cells from spreading. Associate Professor Joe W. Ramos PhD, a cancer biologist at the UH Cancer Center and his team have identified the role of the protein RSK2 in cancer cell migration, part of the process of cancer metastasis.

Target: Cancer

For scientists to improve cancer treatments with targeted therapeutic drugs, they need to be able to see proteins prevalent in the cancer cells. This has been impossible, until now. Thanks to a new microscopy technique, University of Akron researcher Dr. Adam Smith, assistant professor of chemistry, has observed how clusters of epidermal growth factor receptor (EGFR) — a protein abundant in lung and colon cancers, glioblastoma and others — malfunctions in cancer cells.