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The cause of unexplained pain among metal-on-metal hip implant patients is more likely to be tissue damage than wear of the implant, Hospital for Special Surgery researchers have found. The study, performed by Dr. Danyal Nawabi, orthopedic surgery fellow, and research collaborators at HSS, will be reported at the upcoming annual meeting of the American Academy of Orthopaedic Surgeons, March 19-23, in Chicago.

PISCATAWAY, NJ – Some 2-year-olds whose moms used methamphetamine during pregnancy may have an abnormal response to stressful situations, according to a study in the May issue of the Journal of Studies on Alcohol and Drugs.

One of the most southerly populations of polar bears in the world – and the best studied – is struggling to cope with climate-induced changes to sea ice, new research reveals. Based on over 10 years' data the study, published in the British Ecological Society's Journal of Animal Ecology, sheds new light on how sea ice conditions drive polar bears' annual migration on and off the ice.

Research: Use of high potency statins and rates of admission for acute kidney injury: multicenter, retrospective observational analysis of administrative databases

Editorial: Statins in acute kidney injury: friend or foe?

Patients taking high potency statins for high blood pressure are at a 34% higher risk of being hospitalised for acute kidney injury (AKI), compared with those taking low potency statins, a paper published today on bmj.com suggests.

In Africa, issues of vaccine supply, financing, and sustainability require urgent attention if the Millennium Development Goals are to be achieved, according to African experts writing in this week's PLOS Medicine.

Shingai Machingaidze, Charles Wiysonge, and Gregory Hussey from the University of Cape Town in South Africa commend African countries for their progress in immunisation programmes but infectious disease outbreaks, for example, polio and measles outbreaks, as well as high vaccine dropout rates across the region, indicate failures within the immunisation system.

ALBUQUERQUE, N.M. — An alloy that may improve high-temperature electronics in oil and geothermal wells was really a solution in search of a problem.

Sandia National Laboratories first investigated the gold-silver-germanium alloy about 15 years ago as a possible bonding material in a new neutron tube product. But a design change forced Sandia to shelve the material, said Paul Vianco, who has worked in soldering and brazing technology at Sandia for 26 years.

NEW YORK (March 19, 2013) -- Accountable Care Organizations (ACOs), a key feature of the Affordable Care Act (ACA), aim to control health care costs, enhance quality in health care and improve population health. But what does "improving population health" really mean? This is the question asked in a new viewpoint article by Weill Cornell Medical College researchers published in the March 20 issue of the Journal of the American Medical Association (JAMA). The authors argue a clear definition is crucial in order to formulate effective health care and social service policy.

Humans have between 20,000 and 25,000 genes that carry instructions for assembling the proteins that do the work of cells. Work led by St. Jude Children's Research Hospital found that children who inherit certain variations in four particular genes are at much higher risk of developing acute lymphoblastic leukemia (ALL).

Sugar-sweetened sodas, sports drinks and fruit drinks may be associated with about 180,000 deaths around the world each year, according to research presented at the American Heart Association's Epidemiology and Prevention/Nutrition, Physical Activity and Metabolism 2013 Scientific Sessions.

(Boston) –Physician experts in health system issues propose a timely alternative process for harnessing and supporting physician-led innovations to rapidly address front-line health care delivery problems and improve health. Published as a Viewpoint article in the March 20th issue of the Journal of the American Medical Association (JAMA), the authors propose health systems adopt a strategy widely accepted in U.S. industries of "user-led" innovation.

Nurses and midwives can play a critical role in lessening people's risk of cardiovascular diseases, cancers, chronic respiratory disease and diabetes, according to a groundbreaking new report issued by the World Health Organization and co-authored by a UCLA nursing professor.

These four non-communicable disease types account for a combined 60 percent of all deaths worldwide.

SAN FRANCISCO, CA (March 19, 2013) - House paint containing dangerousconcentrations of lead is being sold in Cameroon by an American company – and thecompany is refusing to remove the paint from store shelves.

"There is an immediate need for regulations to restrict the lead content of paint inCameroon to protect public health," said Perry Gottesfeld, Executive Director ofOccupational Knowledge International (OK International) and co-author of a newresearch study about this lead hazard.

Research led by a biology professor in the School of Science at Indiana University-Purdue University Indianapolis (IUPUI) has uncovered a method to produce retinal cells from regenerative human stem cells without the use of animal products, proteins or other foreign substances, which historically have limited the application of stem cells to treat disease and other human developmental disorders.

OAK BROOK, Ill. – March 19, 2013 – In recognition of National Colorectal Cancer Awareness Month, GIE: Gastrointestinal Endoscopy has published a special issue for March on colorectal cancer. The issue includes a practical guide for approaching and managing serrated colon polyps, one of the most common types of polyps, and a study on reducing postpolypectomy bleeding with prophylactic clip closure. GIE: Gastrointestinal Endoscopy is the monthly peer-reviewed scientific journal of the American Society for Gastrointestinal Endoscopy (ASGE).

Parasitoid wasps of the family Braconidae are known for their deadly reproductive habits. Most of the representatives of this group have their eggs developing in other insects and their larvae, eventually killing the respective host, or in some cases immobilizing it or causing its sterility.