Body

Compounds found in pumpkin could potentially replace or at least drastically reduce the daily insulin injections that so many diabetics currently have to endure. Recent research reveals that pumpkin extract promotes regeneration of damaged pancreatic cells in diabetic rats, boosting levels of insulin-producing beta cells and insulin in the blood, reports Lisa Richards in Chemistry & Industry.

Researchers from the European Molecular Biology Laboratory (EMBL) and the University of Michigan have discovered a gene that protects us against a serious kidney disease. In the current online issue of Nature Genetics they report that mutations in the gene cause nephronopthisis (NPHP) in humans and mice. NPHP is a disease marked by kidney degeneration during childhood that leads to kidney failure requiring organ transplantation. The insights might help develop effective, noninvasive therapies.

Chromosome disorders in sex cells cause infertility, miscarriage and irregular numbers of chromosomes (aneuploidy) in neonates. A new study from Karolinska Institutet published in Nature Genetics shows how chromosome disorders can arise when sex cells are formed.

A study appearing in the July issue of the Journal of Periodontology found bacteria commonly found in the mouth and associated with periodontal diseases in the amniotic fluid of some pregnant women.

No one likes a cheater, even a single-celled one.

New research from Rice University shows how cooperative single-celled amoebae rely on family ties to keep cheaters from undermining the health of their colonies. The research appeared in the Proceedings of the National Academy of Sciences in May.

"It's very unusual to get a complete story in biology -- one that marries careful field work with painstaking work in the laboratory -- and that's what we have here," said research co-author Joan Strassmann, chair of Rice's Department of Ecology and Evolutionary Biology.

People who have high cholesterol levels may be much more susceptible to a particular disease transmitted by the bites of ticks, a new study in mice suggests.

Scientists infected mice with Anaplasma phagocytophilum, the bacterium that causes human granulocytic anaplasmosis (HGA), a disease with flu-like symptoms. Bacteria levels were 10 times greater in mice that were genetically predisposed to high cholesterol levels and that were also fed a high-cholesterol diet.

Squamous cell carcinoma (SCC) is a form of nonmelanoma skin cancer, which is the most common type of human malignancy with over 1 million new cases in the USA each year.

In the July 2 issue of the Journal of Clinical Investigation, two separate studies by research teams at Glasgow University and Baylor College of Medicine uncover 2 previously unidentified regulators of SCC development, providing insights into the development of this potentially lethal disease.

Scientists will only make real breakthroughs in children’s medicine if they include children in research programmes as well as adults, according to a leading paediatric expert.

Professor John Warner was speaking today at the opening of the Paediatric Research Unit, the UK’s first unit solely devoted to paediatric clinical research. The unit is run by researchers from Imperial College London and St Mary’s Hospital, and it is based next to the hospital’s paediatric wards in Paddington.

A virus that has been specifically designed by scientists to be safe to normal tissue but deadly to cancer is showing early promise in a preliminary study, researchers said today at the ESMO Conference Lugano (ECLU), Switzerland, 5-8 July 2007.

The virus, called NV1020, is a type of herpes simplex virus modified so that it selectively replicates in virus cells, killing them in the process.

The Ugandan government wants to change the law to allow Mabira Forest Reserve, the 30,000 hectare rainforest in Uganda which has been protected since 1932, to be carved up and a quarter of it used for sugar cane production by huge firms, notably the Mehta Group, which has close ties to politicians within and outside the country.

The forest is home to nearly one third of Uganda's bird life. Sugar cane is a notoriously un-economical crop.

In some regions of Central Europe, salad dressing is made with pumpkin seed oil, which has a strong characteristic nutty flavor and striking color properties - in the bottle it appears red, but it looks green in a salad dressing.

A world leader in medical implants calls for a rethink in our approach to building medical implants.

Currently so-called biomaterials are chosen because they are reasonably successful at hiding from the body’s immune system, and are consequently not rejected. All the same, within a month of implanting them, the body isolates implants by wrapping them in a collagenous, avascular sac. Materials are considered to be ‘biocompatible’ if this sac is not too thick.

Independent research, involving over 3 million Italians, conducted by Henley Management College and the University of Milan has concluded that the prescription costs for men over the age of 65 is significantly higher than it is for women.

The primary objective of this study was to make the first step in the modelling of pharmaceutical demand in Italy to improve the governance of prescribing funds.

We all share our genetic make up with relatives, but should we also share ownership of the results of DNA analysis or should this knowledge be considered private?

Dr Anneke Lucassen, a clinical geneticist at the University of Southampton, believes that if anyone is to own genetic information, it has to be all those who have inherited it and, more importantly, it must be available to all those who might be at risk.

The question, she says, is how to balance a right to privacy with disclosing risks to others.

Should a ban on smoking exempt people who do it for 'cultural' reasons? What if the science regarding the detrimental effects of certain types of smoking is inconclusive?

This is an issue lawmakers in the UK will have to struggle with as advocates try to get hookah smoking exempted from England’s smoking ban.