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Nanotechnology: Learning from past mistakes

Washington, DC — A new expert analysis in Nature Nanotechnology questions whether industry, government and scientists are successfully applying lessons learned from past technologies to ensure the safe and responsible development of emerging nanotechnologies.

The study applies the 12 "late lessons from early warnings," published by the European Environment Agency (EEA) in 2001, to the emerging field of nanotechnology. EEA's "lessons" are drawn from case studies that include the introduction of ozone-damaging halocarbons and of environmentally persistent and toxic PCBs.

American Chemical Society's Weekly PressPac -- July 16, 2008

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"Snow flea antifreeze protein" could help improve organ preservationJournal of the American Chemical Society

Mangroves key to saving lives

The replanting of mangroves on the coasts of the Philippines could help save many of the lives lost in the 20-30 typhoons that hit the islands annually. This is one of the numerous reasons for the 'urgent need for immediate and massive mangrove replanting' that J.H. Primavera from the Southeast Asian Fisheries Development Center and J.M.A. Esteban from De La Salle University, both in the Philippines, cite in a paper published online in the Springer journal Wetlands Ecology and Management(1).

Massive greenhouse gases may be released as destruction, drying of world wetlands worsens: UN

Leading world scientists convene in Brazil July 21-25 amid growing concern that evaporation and ongoing destruction of world wetlands, which hold a volume of carbon similar to that in the atmosphere today, could cause them to exhale billows of greenhouse gases.

Stanford study of dark-skinned mice leads to protein linked to bone marrow failure in humans

STANFORD, Calif. - The study of dark-skinned mice has led to a surprising finding about a common protein involved in tumor suppression, report researchers at the Stanford University School of Medicine. The results may lead to new treatments for bone marrow failure in humans.

The genetics of the white horse unraveled

The white horse is an icon for dignity which has had a huge impact on human culture across the world. An international team led by researchers at Uppsala University has now identified the mutation causing this spectacular trait and show that white horses carry an identical mutation that can be traced back to a common ancestor that lived thousands of years ago. The study is interesting for medical research since this mutation also enhance the risk for melanoma. The paper is published on July 20 on the website of Nature Genetics.

Discovery of a mechanism that regulates cell movement

A study performed by researchers at the Institute for Research in Biomedicine (IRB Barcelona), in collaboration with researchers at the Instituto de Biología Molecular of the CSIC, reveal a mechanism that controls the movement of cells in a tissue by regulating cell adhesion. This same mechanism may be defective in diseases such as cancer and its metastasis, when tumour cells lose their adhesion to neighbouring cells and migrate through the organism. The results of this research have been published in this week's Nature Cell Biology.

Class of antibiotics can enhance gene-silencing tool

A way to turn off one gene at a time has earned acceptance in biology laboratories over the last decade. Doctors envision the technique, called RNA interference, as a tool to treat a variety of diseases if it can be adapted to humans.

Emory University researchers have discovered that antibiotics known as fluoroquinolones can make RNA interference more effective in the laboratory and reduce potential side effects. The results will be published online this week in the journal Nature Biotechnology.

Still puzzling: Best care for the frail and elderly with coronary artery disease

DURHAM, N.C. – A new study from Duke University Medical Center finds that patients treated solely with medications after suffering from chest pain, heart attack or coronary artery disease are more likely to die during the first year following their initial hospitalization.

Researchers grow human blood vessels in mice from adult progenitor cells

For the first time, researchers have successfully grown functional human blood vessels in mice using cells from adult human donors — an important step in developing clinical strategies to grow tissue, researchers report in Circulation Research: Journal of the American Heart Association.

Analysis of quickly stopped Rx orders provides new tool for reducing medical errors

PHILADELPHIA –By studying medication orders that are withdrawn ("discontinued") by physicians within 45 minutes of their origination, researchers at The University of Pennsylvania School of Medicine have demonstrated a systematic and efficient method of identifying prescribing errors. The method, they say, has value to screen for medication errors and as a teaching tool for physicians and physicians-in-training. The report is published in the July/August 2008 issue of the Journal of the American Medical Informatics Association.

Averting postsurgical infections in kids: Give antibiotics within hour before first incision

Giving children preventive antibiotics within one hour before they undergo spinal surgery greatly reduces the risk for serious infections after the surgery, suggests a Johns Hopkins study to be published in the August issue of Pediatric Infectious Disease Journal (also available online ahead of print).

Studies refute common stereotypes about obese workers

EAST LANSING, Mich. — New research led by a Michigan State University scholar refutes commonly held stereotypes that overweight workers are lazier, more emotionally unstable and harder to get along with than their "normal weight" colleagues.

With the findings, employers are urged to guard against the use of weight-based stereotypes when it comes to hiring, promoting or firing.

Molecular hula hoop

Humans have long been trying to make the dream of nanoscopic robots come true. The dream is, in fact, taking on some aspects of reality. Nanoscience has produced components for molecular-scale machines. One such device is a rotor, a movable component that rotates around an axis. Trying to observe such rotational motion on the molecular scale is an extremely difficult undertaking. Japanese researchers at the Universities of Osaka and Kyoto have now met this challenge.

CSHL scientists correlate enzyme expression levels with chemotherapy drug response

Why do cancer patients develop resistance to chemotherapy drugs, sometimes abruptly, after a period in which the drugs seem to be working well to reduce tumors or hold them in check? Although largely a mystery to scientists, the result when this occurs is all too familiar: patients relapse and in many cases die when their cancers become resistant.