Body

OAK BROOK, Ill. – A minimally invasive treatment for a common cause of male infertility can significantly improve a couple's chances for pregnancy, according to a new study published in the August issue of Radiology. The study, conducted at the University of Bonn in Germany, also found that the level of sperm motility prior to treatment is a key predictor of success.

OAK BROOK, Ill. – The simple application of a pain-relieving gel may reduce the breast discomfort some women experience during mammography exams, according to the results of a clinical trial published in the online edition of Radiology.

Arlington, Virginia (July 22, 2008) – Researchers in Madagascar have confirmed the existence of a population of greater bamboo lemurs more than 400 kilometers (240 miles) from the only other place where the Critically Endangered species is known to live, raising hopes for its survival.

The discovery of the distinctive lemurs with jaws powerful enough to crack giant bamboo, their favorite food, occurred in 2007 in the Torotorofotsy wetlands of east central Madagascar, which is designated a Ramsar site of international importance under the 1971 Convention on Wetlands.

The exponential growth of diverse types of biological data presents the research community with an unprecedented challenge to keep the flood of biological data as accessible, up-to-date, and integrated as possible. But it also presents an unprecedented opportunity to cultivate new models of data curation and exchange by engaging the direct participation of the community. In a new article published this week in PLoS Biology, "WikiPathways: Pathway Editing for the People," Alexander R.

International Monetary Fund (IMF) loans were associated with a 16.6% rise in death rates from tuberculosis (TB) in the former Soviet Union and Central and Eastern European countries between 1992 and 2002, finds a study in this week's PLoS Medicine.

The study, by David Stuckler and colleagues from the University of Cambridge, UK, and Yale University, USA, also found that IMF loans were linked with a 13.9% increase in the number of new cases of TB per year and a 13.2% increase per year in the total number of people with the disease.

Group A rotavirus in Kenyan children

Combining prospective hospital-based surveillance with demographic data in Kilifi, Kenya, James Nokes (of the KEMRI-Wellcome Trust Research Programme) and colleagues assess the burden of rotavirus diarrhoea in young children. They find that over 2% of children in Kilifi are admitted to hospital with group A rotavirus diarrhoea in the first 5 years of life. "This translates into over 28,000 vaccine-preventable hospitalisations per year across Kenya," say the authors, "and is likely to be a considerable underestimate."

The Millennium Development Goal (MDG) to halt and begin to reverse the incidence of malaria globally is unlikely to be met, according to Wellcome Trust Principal Research Fellow Professor Bob Snow. The statement comes in a report published today in the open access journal PLoS Medicine.

The eight MDGs were established by the United Nations in 2000 with a view to tackling global poverty and health inequality. Goal 6 included the target to "halt and begin to reverse the incidence of malaria and other major diseases".

STANFORD, Calif. - Plants could act as safe, speedy factories for growing antibodies for personalized treatments against a common form of cancer, according to new findings from the Stanford University School of Medicine. The findings came in the first human tests of an injectable vaccine grown in genetically engineered plants.

The treatments, which would vaccinate cancer patients against their malignant cells, could lead to earlier personalized therapy to tackle follicular B-cell lymphoma, an immune-system malignancy diagnosed in about 16,000 people each year.

After completing one of the longest running experiments ever done on a lake, researchers from the University of Alberta, University of Minnesota and the Freshwater Institute, contend that nitrogen control, in which the European Union and many other jurisdictions around the world are investing millions of dollars, is not effective and in fact, may actually increase the problem of cultural eutrophication.

TEMPE, Ariz. – The greatest danger in a pandemic flu outbreak is that it could spread quickly and devastate a broad swath of people across the United States before there is much of a chance to react. The result could be a nation brought to its knees by a disease run rampant.

SMITHVILLE, Texas - An abundant chromosomal protein that binds to damaged DNA prevents cancer development by enhancing DNA repair, researchers at The University of Texas M. D. Anderson Cancer Center report online this week in the Proceedings of the National Academies of Science.

The protein, HMGB1, was previously hypothesized to block DNA repair, senior author Karen Vasquez, Ph.D., associate professor in M. D. Anderson's Department of Carcinogenesis at the Science Park - Research Division in Smithville, Texas.

CAMBRIDGE, Mass. -- MIT biological engineers have developed a new imaging system that allows them to see cells that have undergone a specific mutation.

The work, which could help scientists understand how precancerous mutations arise, marks the first time researchers have been able to pinpoint the number and location of mutant cells—cells with a particular mutation—in intact tissue. In this case, the researchers worked with mouse pancreatic cells.

ST. PAUL, Minn. – Taking the epilepsy drug topiramate alone or along with other epilepsy drugs during pregnancy may increase the risk of birth defects, according to a study published in the July 22, 2008, issue of Neurology®, the medical journal of the American Academy of Neurology.

Mild memory impairment may be associated with central auditory processing dysfunction, or difficulty hearing in complex situations with competing noise, such as hearing a single conversation amid several other conversations, according to a report in the July issue of Archives of Otolaryngology–Head & Neck Surgery, one of the JAMA/Archives journals.

Individuals who visit dermatology clinics for tattoo removal are more likely to be women than men, and may be motivated by the social stigma associated with tattoos and negative comments by others, according to a report in the July issue of Archives of Dermatology, one of the JAMA/Archives journals.