Body

UCLA and biotech company develop first blood test to measure key hormone that regulates iron

FINDINGS:

UCLA and Intrinsic LifeSciences, a San Diego biotech company, developed the first method to measure the hormone, hepcidin, which regulates the absorption of dietary iron and its distribution in the body. This new blood test will help clinicians manage chronic conditions affecting millions of people worldwide such as anemias and iron overload diseases.

IMPACT:

Coronary CTA costs less than standard of care for triaging women with acute chest pain

Non-invasive coronary CT angiography (CTA) is more cost-effective than current tests for diagnosing women with low risk of a heart attack who come to the emergency room with acute chest pain, according to a recent study conducted by researchers at Harvard University in Cambridge, MA.

Early treatment is key to combating hepatitis C virus

Montreal, August 8, 2008 - Canadian researchers have shown that patients who receive early treatment for Hepatitis C virus (HCV) within the first months following an infection, develop a rapid poly-functional immune response against HCV similar to when infection is erradicted spontaneously, according to a new study published in the Journal of Virology. Therefore, early treatment can restore immune response against HCV and help eliminate the virus rapidly. This new discovery of the mechanisms of viral eradication could contribute to the development of new treatments.

How nonstick bugs evade natural fly paper

There are few things more irritating than a fly buzzing around the house. South Africans have an unconventional solution to the problem. They hang up a bunch of Roridula gorgonias leaves. Attracted to the shiny adhesive droplets on the leaf's hairs, the hapless pest is soon trapped by the natural flypaper. However, this is not the end of the story. Each R. gorgonias plant is home to a population of Pameridea roridulae (mirid bugs), which dine on the trapped insects. Yet the mirid bugs successfully evade their host's sticky clutches.

Fuel from cellulose

Statement of concern on detention of Drs. Kamiar and Arash Alaei by Iranian authorities

Boston, MA -- Barry R. Bloom, Dean of the Harvard School of Public Health, today expressed "deep concern regarding the detention by Iranian authorities of Dr. Kamiar Alaei, a 2007 Masters of Science graduate of our School, and of his brother, Dr. Arash Alaei. The brothers are Iranian physicians working on the prevention and treatment of HIV/AIDS, an important public health problem in their country."

Red all over: how the color red affects a referee's judgment

Many sports teams select their uniforms based on the mascot, city or country they are representing, not on a referee's preference or bias. But a new study has found that choosing the color red for a uniform in competitive sports can actually affect the referee's split-second decision-making ability and even promote a scoring bias.

Eat oily fish at least once a week to protect your eyesight in old age

Eating oily fish once a week may reduce age-related macular degeneration(AMD) which is the major cause of blindness and poor vision in adults inwestern countries and the third cause of global blindness, according toa study published today in the American Journal of Clinical Nutrition.

A one-stop shop for minimal information standards

More than 20 grass-roots standardisation groups, led by scientists at the European Bioinformatics Institute (EMBL-EBI) and the Centre for Ecology & Hydrology (CEH), have combined forces to form the "Minimum Information about a Biomedical or Biological Investigation" (MIBBI) initiative (www.mibbi.org). Their aim is to harmonise standards for high-throughput biology, and their methodology is described in a Commentary article, published today in the journal Nature Biotechnology.

First step towards switching off breast cancer and leukaemia

Australian scientists have identified a way to 'switch off' a molecule, a key player in the molecular processes that trigger breast cancer and certain forms of leukaemia.

The molecule, known as Gab2, operates downstream of a major breast cancer oncogene, HER2, the target of the drug Herceptin.

A research team from the Garvan Institute of Medical Research, led by Professor Roger Daly, has found a novel way of blocking signals to and from Gab2, preventing it from fulfilling its role in cell proliferation. The finding is published online today in the EMBO Journal.

Asthma, outdoor air quality and the Olympic Games

As we come close to the Beijing Olympic Games, a review article, http://www.cmaj.ca/cgi/rapidpdf/cmaj.080982, in CMAJ (Canadian Medical Association Journal) reminds us that the heat and humidity in the Beijing region will present a formidable challenge to all athletes. Moreover, poor quality of air can also affect all athletes, especially those with asthma.

Tiny invasive snail impacts Great Lakes, alters ecology

Long a problem in the western U.S., the New Zealand mud snail currently inhabits four of the five Great Lakes and is spreading into rivers and tributaries, according to a Penn State team of researchers. These tiny creatures out-compete native snails and insects, but are not good fish food replacements for the native species.

How non-stick bugs evade natural fly paper

There are few things more irritating than a fly buzzing around the house. South Africans have an unconventional solution to the problem. They hang up a bunch of Roridula gorgonias leaves. Attracted to the shiny adhesive droplets on the leaf's hairs, the hapless pest is soon trapped by the natural flypaper. However, this is not the end of the story. Each R. gorgonias plant is home to a population of Pameridea roridulae (mirid bugs), which dine on the trapped insects. Yet the mirid bugs successfully evade their host's sticky clutches.

Testosterone key to disease transmission

High levels of testosterone may be a key factor in spreading disease among mice, according to biologists. The findings could help explain why males in a population are often more likely to get infected, and transmit disease.

Previous research has linked testosterone, the male sex hormone, to immune system suppression. Studies have shown that males, compared to females, experience more bouts of disease, and account for a larger share of disease transmission. However, it is not fully clear what makes males such super-spreaders of disease.

Brown tree snake could mean Guam will lose more than its birds

In the last 60 years, brown tree snakes have become the embodiment of the bad things that can happen when invasive species are introduced in places where they have few predators. Unchecked for many years, the snakes caused the extinction of nearly every native bird species on the Pacific island of Guam.

A variety of other damage has been directly attributed to brown tree snakes, including large population losses among other native animal species in Guam's forests, attacks on children and pets, and electrical power outages.