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Physician-researchers from the Cardiac Center at The Children's Hospital of Philadelphia (CHOP) presented new findings on pediatric cardiovascular disease at the American Heart Association's Scientific Sessions 2014 in Chicago. Among many other topics, they investigated using automated external defibrillators in infants, long-term cardiac risk in surgical survivors of the Fontan operations for congenital heart disease, and whether centers that perform more cardiac catheterizations tend to have better outcomes.

Alexandria, Va., USA - Today, the International and American Associations for Dental Research (IADR/AADR) published a special themed issue of the Journal of Dental Research (JDR) centered on novel dental biomaterials and technologies. Although the Associations have published clinical supplements to the JDR, this is the first special themed issue the Associations have published.

New research has found that one of the world's most prolific bacteria manages to afflict humans, animals and even plants by way of a mechanism not before seen in any infectious microorganism -- a sense of touch. This unique ability helps make the bacteria Pseudomonas aeruginosa ubiquitous, but it also might leave these antibiotic-resistant organisms vulnerable to a new form of treatment.

Peruvian coastal waters may provide suitable habitat that may help the recovery of endangered South Pacific green turtles, according to a study published November 19, 2014 in the open-access journal PLOS ONE by Ximena Velez-Zuazo from University of Puerto Rico and colleagues.

Green turtles inhabit tropical and subtropical coastal waters around the world. The authors of this study worked to identify suitable habitat for the endangered species by measuring two populations off the Peruvian coast from 2010 to 2013 in potentially important feeding grounds.

Florida harvester ants move and construct a similar subterranean nest about once a year, according to a study published November 19, 2014 in the open-access journal PLOS ONE by Walter Tschinkel from Florida State University.

The Florida harvester ant excavates up to 2 meter deep nests in the sandy soils of the Gulf and Atlantic coastal plains. Scientists tracked and mapped nest relocations of over 400 colonies in a north Florida coastal plains pine forest from 2010 to 2013 and monitored the progress of entire relocations of 20 of these nests.

LA JOLLA--Scientists at the Salk Institute have discovered a powerful one-two punch for countering a common genetic mutation that often leads to drug-resistant cancers. The dual-drug therapy--with analogs already in use for other diseases--doubled the survival rate of mice with lung cancer and halted cancer in pancreatic cells.

New York City residents' movement around the city was perturbed, but resumed less than 24-hours after Hurricane Sandy, according to a study published November 19, 2014 in the open-access journal PLOS ONE by Qi Wang and John Taylor from Virginia Tech.

TALLAHASSEE, Fla. -- A new study by a Florida State University biologist shows that bleaching events brought on by rising sea temperatures are having a detrimental long-term impact on coral.

Professor Don Levitan, chair of the Department of Biological Science, writes in the latest issue of Marine Ecology Progress Series that bleaching -- a process where high water temperatures or UV light stresses the coral to the point where it loses its symbiotic algal partner that provides the coral with color -- is also affecting the long-term fertility of the coral.

When the mouse and human genomes were catalogued more than 10 years ago, an international team of researchers set out to understand and compare the "mission control centers" found throughout the large stretches of DNA flanking the genes. Their long-awaited report, published Nov. 19 in the journal Nature suggests why studies in mice cannot always be reproduced in humans. Importantly, the scientists say, their work also sheds light on the function of DNA's regulatory regions, which are often to blame for common chronic human diseases.

Microbiologists at NYU Langone Medical Center say they have what may be the first strong evidence that the natural presence of viruses in the gut -- or what they call the 'virome' -- plays a health-maintenance and infection-fighting role similar to that of the intestinal bacteria that dwell there and make up the "microbiome."

For years, scientists have considered the laboratory mouse one of the best models for researching disease in humans because of the genetic similarity between the two mammals. Now, researchers at the Stanford University School of Medicine have found that the basic principles of how genes are controlled are similar in the two species, validating the mouse's utility in clinical research.

However, there are important differences in the details of gene regulation that distinguish us as a species.

For more than a century, the laboratory mouse (Mus musculus) has stood in for humans in experiments ranging from deciphering disease and brain function to explaining social behaviors and the nature of obesity. The small rodent has proven to be an indispensable biological tool, the basis for decades of profound scientific discovery and medical progress.

TALLAHASSEE, Fla. -- A new line of research from a team at Florida State University is pushing the limits on what the world knows about how human genetic material is replicated and what that means for people with diseases where the replication process is disrupted, such as cancer.

Looking across evolutionary time and the genomic landscapes of humans and mice, an international group of researchers has found powerful clues to why certain processes and systems in the mouse - such as the immune system, metabolism and stress response - are so different from those in people. Building on years of mouse and gene regulation studies, they have developed a resource that can help scientists better understand how similarities and differences between mice and humans are written in their genomes.

Cold Spring Harbor, NY - An international team of researchers led by Professor Thomas R. Gingeras of Cold Spring Harbor Laboratory (CSHL) and Roderic Guigo (Centre For Genomic Regulation, Barcelona) has identified some 6600 genes whose level of expression varies within a comparatively restricted range in humans and mice.