Body

Longer work hours for moms mean less sleep, higher BMIs for preschoolers

CHAMPAIGN, Ill. -- The majority of preschoolers may not be getting the amount of sleep they need each night, placing them at higher risk of being overweight or obese within a year, according to a new study.

An Ebola virus protein can cause massive inflammation and leaky blood vessels

Ebola GP protein covers the virus' surface and is shed from infected cells during infection. A study published on November 20th in PLOS Pathogens reports that shed GP can trigger massive dysregulation of the immune response and affect the permeability of blood vessels

Staying ahead of the game: Pre-empting flu evolution may make for better vaccines

An international team of researchers has shown that it may be possible to improve the effectiveness of the seasonal flu vaccine by 'pre-empting' the evolution of the influenza virus.

In a study published today in the journal Science, the researchers, led by the University of Cambridge, describe how an immunological phenomenon they refer to as a 'back boost' suggests that it may be better to pre-emptively vaccinate against likely future strains than to use a strain already circulating in the human population.

Breakthrough in managing yellow fever disease

RIVERSIDE, Calif. - Yellow fever is a disease that can result in symptoms ranging from fever to severe liver damage. Found in South America and sub-Saharan Africa, each year the disease results in 200,000 new cases and kills 30,000 people. About 900 million people are at risk of contracting the disease.

Breakthrough in managing yellow fever disease

RIVERSIDE, Calif. - Yellow fever is a disease that can result in symptoms ranging from fever to severe liver damage. Found in South America and sub-Saharan Africa, each year the disease results in 200,000 new cases and kills 30,000 people. About 900 million people are at risk of contracting the disease.

Evolution: The genetic connivances of digits and genitals

During the development of mammals, the growth and organization of digits are orchestrated by Hox genes, which are activated very early in precise regions of the embryo. These "architect genes" are themselves regulated by a large piece of adjacent DNA. A study led by Denis Duboule, professor at the University of Geneva (UNIGE) and the Federal Institute of Technology in Lausanne (EPFL), Switzerland, reveals that this same DNA regulatory sequence also controls the architect genes during the development of the external genitals.

Running really can keep you young, says CU-Boulder-Humboldt State study

If you are an active senior who wants to stay younger, keep on running.

A new study involving the University of Colorado Boulder and Humboldt State University shows that senior citizens who run several times a week for exercise expend about the same amount of energy walking as a typical 20-year-old.

Dizzying heights: Prehistoric farming on the 'roof of the world'

Animal teeth, bones and plant remains have helped researchers from Cambridge, China and America to pinpoint a date for what could be the earliest sustained human habitation at high altitude.

Archaeological discoveries from the 'roof of the world' on the Tibetan Plateau indicate that from 3,600 years ago, crop growing and the raising of livestock was taking place year-round at hitherto unprecedented altitudes.

Himalaya tectonic dam with a discharge

The Himalaya features some of the most impressive gorges on Earth that have been formed by rivers. The geologic history of the famous Tsangpo Gorge, in the eastern Himalaya, now needs to be rewritten.

New study reveals why some people may be immune to HIV-1

Doctors have long been mystified as to why HIV-1 rapidly sickens some individuals, while in others the virus has difficulties gaining a foothold. Now, a study of genetic variation in HIV-1 and in the cells it infects reported by University of Minnesota researchers in this week's issue of PLOS Genetics has uncovered a chink in HIV-1's armor that may, at least in part, explain the puzzling difference -- and potentially open the door to new treatments.

Tropical rickettsial illnesses associated with adverse pregnancy outcomes

Bangkok (Thailand)- A recent study from the Thai-Myanmar border highlights the severe and previously under-reported adverse impact of readily treatable tropical rickettsial illnesses, notably scrub typhus and murine typhus, on pregnancy outcomes, finding that more than one third of affected pregnancies resulted either in stillbirth or premature and/or low birth weight babies.

University of Kentucky reports HIV/AIDS drugs could be repurposed to treat AMD

LEXINGTON, Ky. (Nov. 20, 2014) - A landmark study published today in the journal Science by an international group of scientists, led by the laboratory of Dr. Jayakrishna Ambati, professor & vice chair of the Department of Ophthalmology & Visual Sciences at the University of Kentucky, reports that HIV/AIDS drugs that have been used for the last 30 years could be repurposed to treat age-related macular degeneration (AMD), as well as other inflammatory disorders, because of a previously undiscovered intrinsic and inflammatory activity those drugs possess.

Firms pressure sales people to invest in costly internal negotiations: INFORMS study

In many firms sales people spend as much time negotiating internally for lower prices as they do interacting with customers. A new study appearing in the November issue of Marketing Science, a publication of the Institute for Operations Research and the Management Sciences (INFORMS) finds that firms should allow their sales people to "waste" energy on internal negotiations. In fact, it says, firms should make the process wasteful on purpose.

New device reduces scarring in damaged blood vessels

When blood vessels are damaged through surgery, it can trigger an endless cycle of scarring and repair.

"Scar tissue will always form inside the blood vessel and, in many cases, eventually block blood flow," said Guillermo Ameer, professor of biomedical engineering at Northwestern University's McCormick School of Engineering. "Then surgeons have to go back in, eliminate the obstruction, or put in a new graft or stent to restore blood flow. In the case of a prosthetic vascular graft used for bypass surgery, it will scar again and ultimately fail."

Testosterone plays modest role in menopausal women's sexual function

Washington, DC--Levels of testosterone and other naturally-occurring reproductive hormones play a limited role in driving menopausal women's interest in sex and sexual function, according to a new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism.

While testosterone is the main sex hormone in men, women also have small amounts of it. The ovaries naturally produce testosterone. Researchers set out to examine the role the hormone plays in sexual function as women go through menopause.