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Fame and achievement in performance-related careers may be earned at the cost of a shorter life, according to a study published online today in QJM: An International Journal of Medicine.

Adults who resolve and recover from conflict are known to be happier in their romantic relationships but the same does not hold true for teen romances, according to research published April 17 in the open access journal PLOS ONE by Thao Ha and colleagues from the Behavioural Science Institute of Radboud University Nijmegen, Netherlands.

A new text-mining algorithm can help identify the most relevant scientific research for a public database that reveals the effects of environmental chemicals on human health, according to research published April 17 in the open access journal PLOS ONE by Allan Peter Davis, Thomas Wiegers and colleagues from North Carolina State University.

Athens, Ga. – Many dog owners have their pets spayed or neutered to help control the pet population, but new research from the University of Georgia suggests the procedure could add to the length of their lives and alter the risk of specific causes of death.

Looking at a sample of 40,139 death records from the Veterinary Medical Database from 1984-2004, researchers determined the average age at death for intact dogs—dogs that had not been spayed or neutered—was 7.9 years versus 9.4 years for sterilized dogs. The results of the study were published April 17 in PLOS ONE.

Ever since the appetite-regulation hormone called leptin was discovered in 1994, scientists have sought to understand the mechanisms that control its action. It was known that leptin was made by fat cells, reduced appetite and interacted with insulin , but the precise molecular details of its function —details that might enable the creation of a new treatment for obesity — remained elusive.

SEATTLE, WA, and QUEBEC CITY, QC, April 17, 2013 – IDRI (Infectious Disease Research Institute), a Seattle-based non-profit research organization that is a leading developer of adjuvants used in vaccines combating infectious disease, and Medicago Inc. (TSX: MDG; OTCQX: MDCGF), a biopharmaceutical company focused on developing highly effective and competitive vaccines based on proprietary manufacturing technologies and Virus-Like Particles (VLPs), today reported positive interim results from a Phase I clinical trial for an H5N1 Avian Influenza VLP vaccine candidate ("H5N1 vaccine").

CAMBRIDGE, MA -- Osteoarthritis, which affects at least 20 percent of adults in the United States, leads to deterioration of cartilage, the rubbery tissue that prevents bones from rubbing together. By studying the molecular properties of cartilage, MIT engineers have now discovered how the earliest stages of arthritis make the tissue more susceptible to damage from physical activities such as running or jumping.

New York, NY—April 17, 2013—Columbia Engineering researchers, led by Dimitris Anastassiou, Charles Batchelor Professor in Electrical Engineering and member of the Columbia Initiative in Systems Biology, have developed a new computational model that is highly predictive of breast cancer survival. The team, who won the Sage Bionetworks / DREAM Breast Cancer Prognosis Challenge for this work, published their results -- "Development of a Prognostic Model for Breast Cancer Survival in an Open Challenge Environment" -- in the April 17 issue of Science Translational Medicine.

HIV-infected women in sub-Saharan Africa who fed their babies exclusively with breast milk for more than the first four months of life had the lowest risk of transmitting the virus to their babies through breast milk, according to researchers at Columbia University's Mailman School of Public Health. Women who stopped breast feeding earlier than four months had the highest concentrations of HIV in their breast milk, and those who continued to breastfeed, but not exclusively, had concentration levels in-between the two practices.

Two new reports issuing in Science Translational Medicine (STM) today showcase the potential of teams of scientists working together to solve increasingly complex medical problems. The results demonstrate that better predictors of breast cancer progression than those currently available can be rapidly evolved by running open Big Data Challenges such as The Sage Bionetworks/DREAM Breast Cancer Prognosis Challenge (BCC).

April 17, 2013 — (BRONX, NY) — Researchers at Albert Einstein College of Medicine of Yeshiva University have discovered how the protein that blocks HIV-1 from multiplying in white blood cells is regulated. HIV-1 is the virus that causes AIDS, and the discovery could lead to novel approaches for addressing HIV-1 "in hiding" – namely eliminating reservoirs of HIV-1 that persist in patients undergoing antiretroviral therapy.

Federally funded safety-net clinics for the uninsured lag behind other health care providers in controlling blood pressure among the low-income patients who rely on them for care, a new Michigan State University analysis suggests.

High blood pressure, or hypertension, is a major risk factor for cardiovascular complications including heart disease and stroke, and is especially common and dangerous for patients with diabetes, said lead researcher Adesuwa Olomu, associate professor in the MSU Department of Medicine.

AUGUSTA, Ga. – Pain is an undeniable focal point for patients with sickle cell disease but it's not the best focus for drug development, says one of the dying breed of physicians specializing in the condition.

An international team of researchers has decoded the genome of a creature whose evolutionary history is both enigmatic and illuminating: the African coelacanth. A sea-cave dwelling, five-foot long fish with limb-like fins, the coelacanth was once thought to be extinct. A living coelacanth was discovered off the African coast in 1938, and since then, questions about these ancient-looking fish – popularly known as "living fossils" – have loomed large. Coelacanths today closely resemble the fossilized skeletons of their more than 300-million-year-old ancestors.

Chevy Chase, MD––Hair strands contain valuable information about senior citizens' stress levels that can be used to determine an individual's cardiovascular disease risk, according to a recent study accepted for publication in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism (JCEM).