Body

Nearly 7 in 10 Americans take prescription drugs - Mayo Clinic Proceedings

ROCHESTER, Minn. — Nearly 70 percent of Americans are on at least one prescription drug, and more than half take two, Mayo Clinic and Olmsted Medical Center researchers say. Antibiotics, antidepressants and painkilling opioids are most commonly prescribed, their study found. Twenty percent of patients are on five or more prescription medications, according to the findings, published online in the journal Mayo Clinic Proceedings.

Iron dosing regimens affect dialysis patients' infection risk

Washington, DC (June 20, 2013) — While intravenous iron is critical for maintaining the health of many dialysis patients, administering large doses over a short period of time increases patients' risk of developing serious infections, according to a study appearing in an upcoming issue of the Journal of the American Society of Nephrology (JASN). Smaller doses given for a longer period of time appears to be much safer.

Bacterial DNA may integrate into human genome more readily in tumor tissue

Bacterial DNA may integrate into the human genome more readily in tumors than in normal human tissue, according to a new study from the University of Maryland School of Medicine's Institute for Genome Sciences. Researchers analyzed genomic sequencing data available from the Human Genome Project, the 1,000 Genomes Project and The Cancer Genome Atlas (TCGA). They considered the phenomenon of lateral gene transfer (LGT), the transmission of genetic material between organisms in the absence of sex.

Study finds climate change to shrink bison, profit

MANHATTAN, Kan. -- As temperatures go up, bison get smaller.

Joseph Craine, research assistant professor in the Division of Biology at Kansas State University, examined how climate change during the next 50 years will affect grazing animals such as bison and cattle in the Great Plains. The study, "Long-term climate sensitivity of grazer performance: a cross-site study," was recently published in the peer-reviewed scientific journal PLOS ONE.

Stress from 9/11 linked to nationwide resurgence in smoking among Americans who had quit

NEW YORK (June 20, 2013) -- The 9/11 attacks on America appear to have caused about one million former smokers across the country to take up the habit again and maintain it, according to a Weill Cornell Medical College public health study.

The analysis, published in the June 20 issue of the journal Contemporary Economic Policy, is the first to look at the net costs to society of terrorism-induced smoking in the United States after 9/11 and the 1995 Oklahoma City bombing.

NEJM features IgA nephropathy research from Dr. Robert Wyatt

Memphis, Tenn. (June 20, 2013) – Inflammation in the kidney is a serious, common issue among adults and children in North America. Finding noninvasive ways to properly diagnose, monitor and treat the inflammation may be getting easier thanks to research by Robert J. Wyatt, MD, professor in the Department of Pediatrics at the University of Tennessee Health Science Center (UTHSC). Dr. Wyatt is co-author of a Medical Progress report titled, "IgA Nephropathy" in this week's edition of the New England Journal of Medicine. His co-author is Bruce A.

Light and nanoprobes detect early signs of infection

DURHAM, N.C. -- Duke University biomedical engineers and genome researchers have developed a proof-of-principle approach using light to detect infections before patients show symptoms.

The approach was demonstrated in human samples, and researchers are now developing the technique for placement on a chip, which could provide fast, simple and reliable information about a patient. A diagnostic device based on this chip also could be made portable.

Researchers determine factors that influence spinach contamination pre-harvest

A team of researchers from Texas and Colorado has identified a variety of factors that influence the likelihood of E. coli contamination of spinach on farms prior to harvest. Their research is published in the July 2013 issue of the journal Applied and Environmental Microbiology.

Uncovering quantum secret in photosynthesis

The efficient conversion of sunlight into useful energy is one of the challenges which stand in the way of meeting the world's increasing energy demand in a clean, sustainable way without relying on fossil fuels. Photosynthetic organisms, such as plants and some bacteria, have mastered this process: In less than a couple of trillionths of a second, 95 percent of the sunlight they absorb is whisked away to drive the metabolic reactions that provide them with energy. The efficiency of photovoltaic cells currently on the market is around 20 percent.

The Red Queen was right: we have to run to keep in place

The death of individual species is not the only concern for biologists worried about groups of animals, such as frogs or the "big cats," going extinct. University of California, Berkeley, researchers have found that lack of new emerging species also contributes to extinction.

International study on fragile newborns challenges current practices

Washington, DC – One of the largest clinical trials done in infants with congenital (present at birth) heart diseases, published in the New England Journal of Medicine, shows that the increasingly common practice of using the drug clopidogrel (Plavix®) to reduce shunt-related blood flow issues is not effective in the dose studied.

Study of insect bacteria reveals genetic secrets of symbiosis

Mealybugs only eat plant sap, but sap doesn't contain all the essential amino acids the insects need to survive. Luckily, the bugs have a symbiotic relationship with two species of bacteria – one living inside the other in a situation unique to known biology – to manufacture the nutrients sap doesn't provide.

The net result: The bacteria get a comfy mealybug home, and the bugs get the nutrition they need to live.

Researchers discover how a mutated protein outwits evolution and fuels leukemia

Scientists have discovered the survival secret to a genetic mutation that stokes leukemia cells, solving an evolutionary riddle and paving the way to a highly targeted therapy for leukemia. In a paper published today in Cell, researchers at NYU Langone Medical Center describe how a mutated protein, called Fbxw7, behaves differently when expressed in cancer cells versus healthy cells.

Reports of retained guidewires draw attention to 'never events' in anesthesia

San Francisco, CA. (June 20, 2013) – Retention of guidewires used to place central venous catheters (CVCs) is a complication that is considered always preventable—but nevertheless still happens, according to a report in the July issue of Anesthesia & Analgesia, official journal of the International Anesthesia Research Society (IARS).

Elevated gluten antibodies found in children with autism but no link to celiac disease

NEW YORK, NY (June 20, 2013)—Researchers have found elevated antibodies to gluten proteins of wheat in children with autism in comparison to those without autism. The results also indicated an association between the elevated antibodies and the presence of gastrointestinal symptoms in the affected children. They did not find any connection, however, between the elevated antibodies and celiac disease, an autoimmune disorder known to be triggered by gluten. The results were e-published in the journal PLOS ONE.