Body

Researchers at Karolinska Institutet in Sweden have developed the first method for directly measuring the extent to which drugs reach their targets in the cell. The method, which is described in the scientific journal Science, could make a significant contribution to the development of new, improved drug substances.

Flapping insects build up an electrical charge that may make them more easily snared by spider webs, according to a new study by University of California, Berkeley, biologists.

The positive charge on an insect such as a bee or fly attracts the web, which is normally negatively or neutrally charged, increasing the chances that an insect flying by will contact and stick to the web, said UC Berkeley post-doctoral fellow Victor Manuel Ortega-Jimenez.

CHAMPAIGN, Ill. — Researchers report that they have found a direct genetic link between the remains of Native Americans who lived thousands of years ago and their living descendants. The team used mitochondrial DNA, which children inherit only from their mothers, to track three maternal lineages from ancient times to the present.

The findings are reported in the journal PLOS ONE.

Analysis of three biomarkers in the urine of kidney transplant recipients can diagnose -- and even predict -- transplant rejection, according to results from a clinical trial sponsored by the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health. This test for biomarkers -- molecules that indicate the effect or progress of a disease -- offers an accurate, noninvasive alternative to the standard kidney biopsy, in which doctors remove a small piece of kidney tissue to look for rejection-associated damage.

Violent or antisocial video games like Call of Duty or Grand Theft Auto do not reliably reduce helpful behaviors in players shortly after playing, according to research published July 3 in the open access journal PLOS ONE by Morgan Tear and Mark Nielsen from the University of Queensland, Australia.

Tweet timing can differentiate individual, corporate and bot-controlled Twitter accounts independent of the language or content of a tweet, according to research published July 3 in the open access journal PLOS ONE by Aldo Faisal and Gabriela Tavares from Imperial College London, UK.

Salamanders' capacity to regrow lost limbs may seem infinite when compared with that of humans, but even amongst salamanders, some species regenerate body parts very slowly, while others lose this capacity as they age. Now, researchers have found that salamanders' capacity to regrow a cut tail depends on several small regions of DNA in their genome that impact how wide the tail grows. The results are published July 3 in the open access journal PLOS ONE by Randal Voss and colleagues from the University of Kentucky.

Bacterial flora inhabiting the human gut have become one of the hottest topics in biological research. Implicated in a range of important activities including digestion, fine-tuning body weight, regulating immune response, and producing neurotransmitters affect that brain and behavior, these tiny workers form diverse communities. Hundreds of species inhabit the gut, and although most are beneficial, some can be very dangerous.

A new study has cast doubt on the claim that crabs may have disappeared from Antarctica only to return due to warming seas.

A species of Indonesian parrot can solve complex mechanical problems that involve undoing a series of locks one after another, revealing new depths to physical intelligence in birds.

A team of scientists from Oxford University, the University of Vienna, and the Max Planck Institute, report in PLOS ONE a study in which ten untrained Goffin's cockatoos [Cacatua goffini] faced a puzzle box showing food (a nut) behind a transparent door secured by a series of five different interlocking devices, each one jamming the next along in the series.

New research from Western University unravels a novel means of communication that allows bacteria such as Burkholderia cenocepacia (B. cenocepacia) to resist antibiotic treatment. B. cenocepacia is an environmental bacterium that causes devastating infections in patients with cystic fibrosis (CF) or with compromised immune systems.

Fossil fuel companies have been funding smear campaigns that raise doubts about climate change, writes John Sauven in the latest issue of Index on Censorship magazine.

Environmental campaigner Sauven argues: "Some of the characters involved have previously worked to deny the reality of the hole in the ozone layer, acid rain and the link between tobacco and lung cancer. And the tactics they are applying are largely the same as those they used in the tobacco wars. Doubt is still their product."

New research, published today in The Lancet, highlights important information for health professionals and parents about the factors which may increase the likelihood of a baby being born with a birth defect.

The findings, from researchers at the Universities of Bradford and Leeds, funded by the National Institute for Health Research (NIHR), confirm that the two main factors associated with an increased risk of babies being born with a birth defect are being born to an older mother or to parents who are blood relations.

NEW YORK (July 4, 2013) -- A breakthrough non-invasive test can detect whether transplanted kidneys are in the process of being rejected, as well as identify patients at risk for rejection weeks to months before they show symptoms, according to a study published in The New England Journal of Medicine (NEJM).

GAINESVILLE, Fla. — For years, pilots flying into combat have jammed enemy radar to get the drop on their opponents. It turns out that moths can do it, too.

A new study co-authored by a University of Florida researcher shows hawkmoths use sonic pulses from their genitals to respond to bats producing the high-frequency sounds, possibly as a self-defense mechanism to jam the echolocation ability of their predators.