Body

More than just a kinase: CDK6 in cancer

Cancer in humans is frequently associated with unusually high amounts of one or more proteins responsible for controlling the rate at which cells divide. As an example, excessive amounts of the cyclin-dependent kinase CDK6 are often found in types of cancer such as lymphoma.

Baby corals pass the acid test

Corals can survive the early stages of their development even under the tough conditions that rising carbon emissions will impose on them says a new study from the ARC Centre of Excellence for Coral Reef Studies.

Globally, ocean acidification remains a major concern and scientists say it could have severe consequences for the health of adult corals, however, the evidence for negative effects on the early life stages of corals is less clear cut.

New strategy to disarm the dengue virus brings new hope for a universal dengue vaccine

1. A new strategy that cripples the ability of the dengue virus to escape the host immune system has been discovered by A*STAR's Singapore Immunology Network (SIgN). This breakthrough strategy opens a door of hope to what may become the world's first universal dengue vaccine candidate that can give full protection from all four serotypes of the dreadful virus.

Enhancer RNAs may open new avenues for gene therapy

A study investigating the function of the recently discovered enhancer RNA molecules may open new avenues for gene therapy. According to the study researchers, altering the production and function of these molecules could affect the expression of genes and, in consequence, possibly also the progression of various diseases. Published in the prestigious Molecular Cell on 8 August, the study was carried out in collaboration between the University of California, San Diego and the University of Eastern Finland.

Virus-derived particles target blood cancer

Ottawa researchers have developed unique virus-derived particles that can kill human blood cancer cells in the laboratory and eradicate the disease in mice with few side effects. The study is published in Blood Cancer Journal by co-senior authors Drs. David Conrad and John Bell of the Ottawa Hospital Research Institute (OHRI) and the University of Ottawa (uOttawa).

Study finds 'ray' wings sold to consumers include vulnerable species & can be mislabeled

Genetic testing by DNA Barcoding, has revealed which species are sold under the commercial term 'ray wings' in Ireland and the UK. The blonde ray, given the lowest rating for sustainability in the marine conservation society's good fish guide, was the most widely sold. Samples from the only retailer to label products as originating from more sustainable sources demonstrated high levels of mislabelling, substituted by more vulnerable species. Therefore, consumers cannot make informed purchasing decisions.

Study examines how truck drivers react to marketplace demands for speed and flexibility

NEW YORK CITY — Benjamin Snyder conducted his research in the cab of a truck hauling frozen chicken from Missouri to Virginia.

Snyder, a graduate sociology student in the University of Virginia's Graduate School of Arts & Sciences, will present his paper, "The Professionalized Body: Truck Driving in the Age of Flexibilization," at the 108th Annual Meeting of the American Sociological Association. Snyder explores how truck drivers, as representatives of the American workforce, are reacting to marketplace demands for speed and flexibility.

MRSA strain in humans originally came from cattle

A strain of bacteria that causes skin and soft tissue infections in humans originally came from cattle, according to a study to be published in mBio®, the online open-access journal of the American Society for Microbiology. The researchers who conducted the genetic analysis of strains of Staphylococcus aureus known as CC97 say these strains developed resistance to methicillin after they crossed over into humans around forty years ago. Today, methicillin-resistant S.

Canine distemper virus: An emerging disease in rare Amur tigers

Rare Amur tigers in Russia are succumbing to infection with canine distemper virus (CDV), a pathogen most commonly found in domestic dogs, according to the authors of a study published in mBio®, the online open-access journal of the American Society for Microbiology.

New gene repair technique promises advances in regenerative medicine

MADISON, Wis. — Using human pluripotent stem cells and DNA-cutting protein from meningitis bacteria, researchers from the Morgridge Institute for Research and Northwestern University have created an efficient way to target and repair defective genes.

Writing today (Monday, Aug. 12, 2013) in the Proceedings of the National Academy of Sciences, the team reports that the novel technique is much simpler than previous methods and establishes the groundwork for major advances in regenerative medicine, drug screening and biomedical research.

If you were a preemie, take heed for your heart

Being born prematurely may be linked to important changes in how your heart forms and works as an adult, according to new research in the American Heart Association's journal Circulation.

Researchers tracked 102 premature babies from birth into their 20s. Compared to 132 people born at full-term, the study showed that in adulthood:

Inducing and augmenting labor may be associated with increased risk of autism

DURHAM, N.C. -- Pregnant women whose labors are induced or augmented may have an increased risk of bearing children with autism, especially if the baby is male, according to a large, retrospective analysis by researchers at Duke Medicine and the University of Michigan.

The findings, published in JAMA Pediatrics on Aug. 12, 2013, do not prove cause and effect, but suggest the need for more research, particularly as labor induction and augmentation have been used more frequently in recent years.

Breastfeeding associated with decreased risk of overweight among children in Japan

Breastfeeding appears to be associated with decreased risk of overweight and obesity among school children in Japan, according to a study by Michiyo Yamakawa, M.H.Sc., of the Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Okayama City, Japan, and colleagues.

Induced or augmented childbirth appears to be associated with increased risk for autism

An analysis of North Carolina birth and educational records suggests that induction (stimulating uterine contractions prior to the onset of spontaneous labor) and augmentation (increasing the strength, duration, or frequency of uterine contractions with spontaneous onset of labor) during childbirth appears to be associated with increased odds of autism diagnosis in childhood, according to a study by Simon G. Gregory, Ph.D., of Duke University Medical Center, Durham, N.C., and colleagues.

Vitamin D supplementation does not appear to reduce blood pressure in patients with hypertension

Vitamin D supplementation does not appear to improve blood pressure or markers of vascular health in older patients with isolated systolic hypertension (a common type of high blood pressure), according to a study by Miles D. Witham, Ph.D., of the University of Dundee, Scotland, United Kingdom, and colleagues.