Body

JAMA study: Stroke risk and death rates fall over past 2 decades

Fewer Americans are having strokes and those who do have a lower risk of dying from them finds a new study led by Johns Hopkins Bloomberg School of Public Health researchers.

Physicians struggle to clinically diagnose early HIV infection

Despite the belief that early HIV infection presents with a well recognized flu-like syndrome, most physicians are unable to use clinical skills to differentiate those who should and should not be tested for HIV infection, according to a study published July 15 in Journal of the American Medical Association (JAMA).

History of stroke linked with increased risk of adverse outcomes after non-cardiac surgery

In an analysis that included more than 480,000 patients who underwent elective noncardiac surgery, a history of stroke was associated with an increased risk of major adverse cardiovascular events and death, particularly if time elapsed between stroke and surgery was less than 9 months, according to a study in the July 16 issue of JAMA.

Physicians have higher rate of organ donation registration than general public

A study that included about 15,000 physicians found that they were more likely to be registered as an organ donor compared to the general public, according to a study in the July 16 issue of JAMA.

Study: Body Dysmorphic Disorder patients have higher risk of personal and appearance-based rejection sensitivity

PROVIDENCE, R.I. – In a recent study, researchers at Rhode Island Hospital found that fear of being rejected because of one's appearance, as well as rejection sensitivity to general interpersonal situations, were significantly elevated in individuals with Body Dysmorphic Disorder (BDD). These fears, referred to as personal rejection sensitivity and appearance-based rejection sensitivity, can lead to diminished quality of life and poorer mental and overall health.

Prostate cancer in young men -- More frequent and more aggressive?

ANN ARBOR, Mich. -- The number of younger men diagnosed with prostate cancer has increased nearly 6-fold in the last 20 years, and the disease is more likely to be aggressive in these younger men, according to a new analysis from researchers at the University of Michigan Comprehensive Cancer Center.

Typically, prostate cancer occurs more frequently as men age into their 70s or 80s. Many prostate cancers are slow-growing and many older men diagnosed with early stage prostate cancer will end up dying from causes other than prostate cancer.

Do daughters really cause divorce? Maybe not

DURHAM, N.C. -- In the U.S., couples with daughters are somewhat more likely to divorce than couples with sons. Many scholars have read those numbers as evidence that daughters cause divorce.

But new research from Duke University suggests something quite different may be at play: Girls may be hardier than boys, even in the womb, and may be better able to survive pregnancies stressed by a troubled marriage.

Study finds why some firms are 'named and shamed' by activists

COLUMBUS, Ohio – A new study of the anti-sweatshop campaigns of the 1990s reveals which companies are most likely to become targets of anti-corporate activists.

Researchers found that companies tended to attract the attention of labor activists if they were large, had prominent brand images, or had good corporate reputations. When combined, these factors were especially important.

TGen-led study finds likely origin of lung fungus invading Pacific Northwest

FLAGSTAFF, Ariz. - Cryptococcus gattii, a virulent fungus that has invaded the Pacific Northwest is highly adaptive and warrants global "public health vigilance," according to a study by an international team led by the Translational Genomics Research Institute (TGen).

C. gattii, which likely originated in Brazil, is responsible for dozens of deaths in recent years since it was first found in 1999 on Vancouver Island, British Columbia, Canada, well outside its usual tropical habitats.

Rollout strategy for diagnostic test in India may impact TB

Xpert MTB/RIF, a recently implemented tuberculosis (TB) test, has the potential to control the TB epidemic in India, but only if the current, narrow, implementation strategy is replaced by a more ambitious one that is better funded, also includes the private sector, and better referral networks are developed between public and private sectors, according to new research published in this week's PLOS Medicine.

Molecular 'eat now' signal makes cells devour dying neighbors

A team of researchers has devised a Pac-Man-style power pellet that gets normally mild-mannered cells to gobble up their undesirable neighbors. The development may point the way to therapies that enlist patients' own cells to better fend off infection and even cancer, the researchers say.

A description of the work will be published July 15 in the journal Science Signaling.

BUSM study: Obesity may be impacted by stress

Using experimental models, researchers at Boston University School of Medicine (BUSM) showed that adenosine, a metabolite released when the body is under stress or during an inflammatory response, stops the process of adipogenesis, when adipose (fat) stem cells differentiate into adult fat cells.

Team studies immune response of Asian elephants infected with a human disease

CHAMPAIGN, Ill. — Mycobacterium tuberculosis, the organism that causes tuberculosis in humans, also afflicts Asian (and occasionally other) elephants. Diagnosing and treating elephants with TB is a challenge, however, as little is known about how their immune systems respond to the infection. A new study begins to address this knowledge gap, and offers new tools for detecting and monitoring TB in captive elephants.

Protein's 'hands' enable bacteria to establish infection, research finds

MANHATTAN — When it comes to infecting humans and animals, bacteria need a helping hand.

Kansas State University biochemists have found the helping hand: groups of tiny protein loops on the surface of cells. These loops are similar to the fingers of a hand, and by observing seven individual loops on the surface of E. coli bacterial cells, the researchers found that the loops can open or close to grab iron in the environment.

Researchers find organic pollutants not factor in turtle tumor disease

For nearly four decades, scientists have suspected that persistent organic pollutants (POPs) contributed to a green turtle's susceptibility to the virus that causes fibropapilomatosis (FP), a disease that forms large benign tumors that can inhibit the animal's sight, mobility and feeding ability.