AUGUSTA, Ga. – Cryoprotectants needed to preserve eggs for reproduction need to be given in stages, albeit rapid ones, say scientists who have developed a mathematical model that predicts optimal time for loading and unloading these drugs.
Their studies in Rhesus monkey eggs, which are very similar to human eggs, show that a two-step process of easing into and out of the drugs needed to help protect eggs at subzero temperatures dramatically reduces the amount eggs contract and expand in the process.