In a study published in May 2009 issue of PLoS Pathogens, Manchester and her colleagues show that CPMV interacts with the mammalian protein vimentin — an interaction that scientists can now explore with the idea of using the virus to deliver "cargo," such as drugs, to tumors or other diseased tissues.
"Vimentin was not at all a likely suspect," says Kris Koudelka, a postdoctoral fellow in the Manchester lab and an author of the study. "I had to do many sets of experiments to convince myself and the team that the result was real."