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Study uncovers novel genetic variation linked to increased risk of sudden cardiac arrest

LOS ANGELES – June 30, 2011 – A study by a global consortium of physician-scientists has identified a genetic variation that may predispose people to double the risk of having a sudden cardiac arrest, a disorder that gives little warning and is fatal in about 95 percent of cases. Although previous, smaller studies have identified some genes with a potential association with sudden cardiac arrest, this is the first study large enough to enable scientists to apply results to the general population. Findings are published today by the Public Library of Science (PloS Genetics).

Preventing diabetes damage: Zinc's effects on a kinky, two-faced cohort

ANN ARBOR, Mich.---In type 2 diabetes, a protein called amylin forms dense clumps that shut down insulin-producing cells, wreaking havoc on the control of blood sugar. But zinc has a knack for preventing amylin from misbehaving.

Recent research at the University of Michigan offers new details about how zinc performs this "security guard" function. The findings appear in the July 8 issue of the Journal of Molecular Biology.

Assessing agroforestry's advantages

MADISON, WI, JUNE 30, 2011 -- Agroforestry, the deliberate placement of trees into crop and livestock operations, can help capture substantial amounts of carbon on agricultural lands while providing production and conservation benefits. However, we currently lack tools for accurately estimating current and projected carbon values in these systems.

Worse outcomes for older breast cancer patients with other health problems

Older breast cancer patients with certain other health problems have higher mortality rates than patients without these problems according to a study published online June 30 in the Journal of the National Cancer Institute. The other health problems, or 'comorbidities', include heart attack and other heart-related problems, chronic obstructive pulmonary disease, diabetes, and others.

A different kind of mentor

MADISON, WI, JUNE 30, 2011 -- Mentoring is a recognized tool in career development and advancement. It brings a personal element to what might otherwise be a confusing process. Mentors can provide insight into the unwritten rules and culture of the professional workplace. With the click of a mouse, a student can have access to an ementor, a career professional who can expand the student's career horizon and help navigate their collegiate experience.

BMC conducts high rates of thyroid testing in pregnant women, study finds

(Boston) – A recent study completed by researchers from Boston University School of Medicine (BUSM) and Boston Medical Center (BMC) demonstrates that BMC conducts a high rate of thyroid function testing in pregnant women. The retrospective study, which is currently published online in the Journal of Clinical Endocrinology & Metabolism, showed that if BMC had not done routine thyroid testing on pregnant women, approximately 80 percent of cases of mild hypothyroidism (a condition whereby the thyroid does not produce enough thyroid hormone) would not have been detected.

Pigment patterns from the prehistoric past

Publishing their findings in Science, the researchers have been able to show a remarkable relationship between copper and pigment within exceptionally preserved feathers and other soft tissues.

Results include important species such as the oldest beaked bird yet found, the 120 million year old Confuciusornis sanctus, and also the 110 million year old Gansus yumenensis, which looks similar to the modern Grebe and represents the oldest example of modern birds.

X-rays reveal patterns in the plumage of the first birds

Working at SLAC's Stanford Synchrotron Radiation Lightsource, the researchers examined two fossilized birds. Confuciusornis sanctus, which lived 120 million years ago, was one of many evolutionary links between dinosaurs and birds, sporting the first known bird-like beak. Gansus yumenensis, considered the oldest modern bird, lived more than 100 million years ago and looked a bit like a modern grebe.

Down-under digestive microbes could help lower methane gas from livestock

COLUMBUS, Ohio – The discovery that a bacterial species in the Australian Tammar wallaby gut is responsible for keeping the animal's methane emissions relatively low suggests a potential new strategy may exist to try to reduce methane emissions from livestock, according to a new study.

Globally, livestock are the largest source of methane from human-related activities, and are the third-largest source of this greenhouse gas in the United States, according to the U.S. Environmental Protection Agency.

Penn scientists contribute to X-ray technique for determining fossil pigmentation patterns

An international team including University of Pennsylvania paleontologists is unearthing the appearance of ancient animals by using the world's most powerful X-rays. New research shows how trace metals in fossils can be used to determine the pigmentation patterns of creatures dead for more than a hundred million years.

Telomeres: 2 genes linked to why they stretch in cancer cells

Scientists at Johns Hopkins have provided more clues to one of the least understood phenomena in some cancers: why the "ends caps" of cellular DNA, called telomeres, lengthen instead of shorten.

In a study published online June 30 in Science Express, the Johns Hopkins researchers say they have identified two genes that, when defective, may cause these telomere elongations.

Heart transplant patients at risk for serious skin cancers

A new study published in the American Journal of Transplantation reveals that there is a significant risk of serious skin cancers, including cutaneous squamous cell carcinoma and melanoma, in heart transplant patients.

When people receive heart transplants, they need immune medications to keep their body from rejecting the transplant. The changes to the immune system they experience as a result of the medications can also make them more susceptible to developing cancers.

Why do we share stories, news and information with others?

People often share stories, news, and information with the people around them. We forward online articles to our friends, share stories with our co-workers at the water cooler, and pass along rumors to our neighbors. Such social transmission has been going on for thousands of years, and the advent of social technologies like texting, Facebook, and other social media sites has only made it faster and easier to share content with others. But why is certain content shared more than others and what drives people to share?

CSHL team identifies enzyme that is an important regulator of aggressive breast cancer development

Cold Spring Harbor, NY – Researchers at Cold Spring Harbor Laboratory (CSHL) have identified an enzyme that appears to be a significant regulator of breast cancer development. Called PTPN23, the enzyme is a member of a family called protein tyrosine phosphatases, or PTPs, that plays a fundamental role in switching cell signaling on and off.

Novel analysis method organizes genomic cancer data

The technology that allows scientists to profile the entire genome of individual tumors offers new hope for discovering ways to select the best treatment for each patient's particular type of cancer. However, these profiles produce huge amounts of data, and the volume alone creates unique analytical problems.