Body

New Haven, Conn.—Over one-third of the world's population already lives in areas struggling to keep up with the demand for fresh water. By 2025, that number will nearly double. Some countries have met the challenge by tapping into natural sources of fresh water, but as many examples – such as the much-depleted Jordan River – have demonstrated, many of these practices are far from sustainable.

5 August 2011 | Potsdam: For 20 000 years, climate variability in East Africa has been following a pattern that is evidently a remote effect of the ENSO phenomenon (El Niño Southern Oscillation) known as El Niño/La Niña. During the cold phase of La Niña, there is marginal rainfall and stronger winds in East Africa, while the El Niño warm phase leads to weak wind conditions with frequent rain. Moreover, during the coldest period of the last ice age about 18 000 to 21 000 years ago, East Africa's climate was relatively stable and dry.

A paper co-authored by William Phillip of the University of Notre Dame's Department of Chemical and Biomolecular Engineering and Menachem Elimelech, Robert Goizueta Professor of Environmental and Chemical Engineering at Yale University, appearing in this week's edition of the journal Science offers a critical review of the state of seawater desalination technology.

An international team of researchers led by scientists at Mount Sinai School of Medicine have found that motion sickness on tilting trains can be essentially eliminated by adjusting the timing of when the cars tilt as they enter and leave the curves. They found that when the cars tilt just at the beginning of the curves instead of while they are making the turns, there was no motion sickness. The findings were published online Monday, July 25 in the Federation of American Societies for Experimental Biology (FASEB) Journal.

Researchers at National Jewish Health have discovered a type of cell that may contribute to autoimmune disease and suggests why diseases such as lupus, multiple sclerosis and rheumatoid arthritis strike women more frequently than men. The cells, a subset of immune-system B cells, make autoantibodies, which bind to and attack the body's own tissue. The researchers reported in the August 4, 2011, issue of the journal Blood, that they found higher levels of these cells in elderly female mice, young and old mice prone to autoimmune disease, and humans with autoimmune diseases.

BOZEMAN, Mont. – Researchers led by Montana State University have found a surprising condition that occurs in the lungs after an invasion of a common mold that can cause deadly infections in humans.

In the most oxygen-rich environment in the body, the lungs, the scientists discovered a shortage of oxygen. The shortage resulted from inflammation and invasive growth of the mold, which greatly reduced the oxygen available to the pathogenic mold Aspergillus fumigatus.

Kidney transplant from a living donor, besides of being the best option for young people and those affected by particular conditions, results in increased organ survival and solves in part the organ shortage afflicting Spain since the mid-90 despite the high rate of cadaveric donation. According to the National Transplant Organization in 2010 in Spain 240 living donor kidney transplants were made, which represents 11% of the total. This year the expectation is that this number will grow to about 300, which would be almost about 13-15% of the total.

Washington, DC, August 4, 2011 -- Increased hand hygiene knowledge positively correlates with a decreased risk of transmitting infection among both healthcare workers (HCW) and elementary school children, according to two studies published in the August issue of the American Journal of Infection Control (AJIC), the official publication of APIC - the Association for Professionals in Infection Control and Epidemiology.

Researchers have found a way to turn mouse embryonic stem cells into sperm. This finding, reported in the journal Cell in a special online release on August 4th, opens up new avenues for infertility research and treatment. A Kyoto University team has coaxed mouse embryonic stem cells into sperm precursors, called primordial germ cells (PGCs), and shown that these cells can give rise to healthy sperm. The researchers say that such in vitro reconstitution of germ cell development represents one of the most fundamental challenges in biology.

New research finds that growing blood stem cells in the laboratory for about a week may help to overcome one of the most difficult roadblocks to successful transplantation, immune rejection. The study, published by Cell Press in the August issue of the journal Cell Stem Cell, may lead to more promising therapeutic strategies for transplanting blood stem cells.

Recent studies have shown that the heart contains cardiac stem cells that can contribute to regeneration and healing during disease and aging. However, little is known about the molecules and pathways that regulate these cells. Now, a new study utilizing a heart failure model is providing insight into one way to coax the cardiac stem cells into repairing the damaged heart.

Scientists have identified a mutation that might underlie an extremely rare condition, called "adermatoglyphia," which causes people to be born without any fingerprints. The research, published by Cell Press online August 4th in The American Journal of Human Genetics, not only provides valuable insight into the genetic basis of adermatoglyphia and of typical fingerprint formation but also underscores the usefulness of rare genetic mutations as a tool for investigating unknown aspects of our biology.

Until very recently, it was unclear why infection with malaria causes fever and, under severe circumstances, an infectious death. Although the parasite has an abundance of potentially toxic molecules, no one knew which ones were responsible for the inflammatory syndrome associated with disease. Now, a new study identifies a novel DNA-sensing mechanism that plays a role in the innate immune response to the parasite that causes malaria.

DALLAS – Aug. 4, 2011 – Findings by UT Southwestern Medical Center researchers may suggest new strategies for successful donor adult stem cell transplants in patients with blood cancers such as leukemia, lymphoma and myeloma.