Body

SAN FRANCISCO, CA—August 8, 2011—A scientist at the Gladstone Institutes has discovered how gene regulation can make hearts beat out of sync, offering new hope for the millions who suffer from a potentially fatal heart condition.

In a paper being published this week in the online Early Edition of the Proceedings of the National Academy of Sciences, Gladstone Investigator Benoit G. Bruneau, PhD announces the identity of the molecular regulator that uses electrical impulses to synchronize each heartbeat.

PITTSBURGH, Aug. 8 – Researchers at the University of Pittsburgh School of Dental Medicine are piecing together the process of tooth enamel biomineralization, which could lead to novel nanoscale approaches to developing biomaterials. The findings are reported online this week in the Proceedings of the National Academy of Sciences.

Washington, D.C.—Meteorites hold a record of the chemicals that existed in the early Solar System and that may have been a crucial source of the organic compounds that gave rise to life on Earth. Since the 1960s, scientists have been trying to find proof that nucleobases, the building blocks of our genetic material, came to Earth on meteorites.

EUGENE, Ore. -- (Aug. 8, 2011) -- Shape and alignment are everything. How nanometer-sized pieces fit together into a whole structure determines how well a living cell or an artificially fabricated device performs. A new method to help understand and predict such structure has arrived with the successful use a new imaging tool.

FINDINGS: Whitehead Institute researchers have uncovered a novel association between two fungal recognition receptors on the surface of certain immune cells, called macrophages. The interaction of these receptors (dectin-1 and galectin-3) sheds new light on how the innate immune system discriminates between non-pathogenic and pathogenic fungi.

A female mosquito cannot tell if the male that she has mated with is fertile or 'spermless' and unable to fertilise her eggs, according to a new study from scientists at Imperial College London.

The research, published today in the journal Proceedings of the National Academy of Sciences, could help scientists in their mission to prevent the spread of malaria by interfering with the mosquitoes' ability to reproduce.

PITTSBURGH, Aug. 8 – Researchers at the University of Pittsburgh School of Medicine have identified a molecular pathway that helps explain how an enzyme elevated in asthma patients can lead to increased mucus production and inflammation that is characteristic of the lung condition. Their findings, reported online in this week's Proceedings of the National Academy of Sciences, reveal unique interactions between biological molecules that could be targeted to develop new asthma treatments.

CHICAGO (August 8, 2011) – According to a study published in the August issue of the Journal of the American College of Surgeons, there was an increase in the number of laparoscopic bariatric procedures, an increase in the number of bariatric surgeons and a decrease of inhospital mortality rates between 2003 and 2008. During the past decade, the field of bariatric surgery has changed dramatically and the authors concluded that these trends are due, in part, to an increase in the use of laparoscopic techniques and a greater acceptance of bariatric surgery by patients.

Boulder, CO, USA - An international team of researchers has found the strongest evidence yet that parts of North America and Antarctica were connected 1.1 billion years ago, long before the supercontinent Pangaea formed.

"I can go to the Franklin Mountains in West Texas and stand next to what was once part of Coats Land in Antarctica," said Staci Loewy, a geochemist at California State University, Bakersfield, who led the study. "That's so amazing."

By 2012, an estimated 14 million people will serve as distance caregivers to family members who live across the state, across the region, even across the country.

"No longer are families living just around the corner from each other," says Polly Mazanec, an assistant professor at the Frances Payne Bolton School of Nursing and an advance practice oncology nurse at University Hospitals Case Medical Center's Seidman Cancer Center.

DETROIT – Prenatal pet exposure, a mother's delivery mode and race are influential factors in a child's risk of developing allergies by age 2, according to a Henry Ford Hospital study.

In a study believed to be the first of its kind, Henry Ford researchers found that babies who have indoor prenatal pet exposure have a pattern of lower levels of the antibody Immunoglobulin E, or IgE, between birth and age 2. IgE is linked to the development of allergies and asthma.

Key findings:

Parents often ask their doctors for advice on toilet training young children, and a new article in CMAJ (Canadian Medical Association Journal) (pre-embargo link only) http://www.cmaj.ca/site/embargo/cmaj110830.pdf summarizes current approaches and evidence to help physicians respond to these queries.

It's pretty much a given that the more educated someone becomes, the more likely they are to question their religious beliefs, stop going to church and even abandon their faith entirely.

Or is it?

A new University of Nebraska-Lincoln study challenges that age-old notion with findings that show education actually has a positive effect on Americans' churchgoing habits, their devotional practices, their emphasis on religion in daily life and their support for religious leaders to weigh in on the issues of the day.

PHILADELPHIA – In the latest issue of Nature, researchers at the Perelman School of Medicine at the University of Pennsylvania clarify the role of two proteins key to T-cell development. They found that one well-known protein called Notch passes off much of its role during T-cell maturation to another protein called TCF-1. T cells are required for many aspects of immunity, and understanding how these proteins influence the production of infection-fighting cells could improve treatments for immune-suppressed patients.

Almost everything we do leaves a digital trace, whether we send an email to a friend or make a purchase online. That includes law-abiding citizens — and criminals. And with digital information multiplying by the second, there are seemingly endless amounts of information for criminal investigators to gather and process.