African-Americans are disproportionately affected by hypertension, a puzzle whose solutions has eluded medical science. It may be how people respond to inflammation.
In a study published in Vascular Health and Risk Management, lead author Michael Brown and his team tested the effects of TNF-ά, a protein that causes inflammation when cells are damaged, on endothelial cells, which line blood vessels, in both African-Americans and Caucasians, to determine whether the inflammation affected the cells differently.