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Panel blasts federal nanotech risk research strategy

Washington, DC – A National Research Council (NRC) committee today issued a highly critical report describing serious shortfalls in the Bush administration's strategy to better understand the environment, health and safety (EHS) risks of nanotechnology and to effectively manage those potential risks.

Parents be aware this holiday season: Magnets in children's toys pose significant health risk

CINCINNATI – While the danger of magnets for children is increasingly recognized, they don't receive treatment for swallowing them as quickly as needed, and parents don't receive sufficient warning on toys, according to a new study.

Novel technique for fluorescence tomography of tumors in living animals

Fluorescent molecules – i.e. substances which can be stimulated to emit light – are extremely valuable tools in biological research and medical diagnosis. Fluorescence can be used for instance to analyze the regulation and expression of genes, to locate proteins in cells and tissues, to follow metabolic pathways and to study the location and migration of cells. Of particular importance is the combination of fluorescence imaging with novel techniques that allow tomographic three-dimensional visualization of objects in living organisms.

Scientists resolve to crack down on fraud

Public confidence in the honesty of scientists is being harmed by a small minority of researchers who behave badly, a conference heard last week. European research organisations agreed to work more closely to tackle the problem of fraud and other misconduct in science.

Surge in older cancer survivors expected as baby boomers age

STORRS, CT – The United States could be faced with a national health care crisis in the coming decades as the country's baby boomer population ages and a growing number of older adults find themselves diagnosed with and living longer with cancer.

That is the position of a team of researchers from across the country who believe current prevention measures, screening, treatments, and supportive care for older patients at risk of or dealing with cancer are lacking in the US.

Overweight children at increased risk of arm and leg injuries following motor vehicle crash

Children who are overweight or obese are over two and a half times more likely to suffer injuries to their upper and lower extremities following a motor vehicle crash compared with normal weight children, according to a new report from the Johns Hopkins Bloomberg School of Public Health's Center for Injury Research and Policy. Overweight and obese children were overall more likely to experience injury to any body part following a crash; however this difference was not statistically significant.

Long-term use of diabetes drugs by women significantly increases risk of fractures

A group of drugs commonly used to treat diabetes can double the risk of bone fractures in women, according to a new study by the University of East Anglia (UEA) and Wake Forest University.

Published today in the Canadian Medical Association Journal (CMAJ), the findings show that use of thiazolidinediones for more than one year by women with type 2 diabetes significantly reduces bone density, resulting in the risk of fractures being doubled.

The researchers found no increased risk of fractures among men, however.

Two common diabetes drugs double the risk of fractures in women

Two common diabetes drugs — rosiglitazone and pioglitazone — are linked to higher fracture rates in women, according to a meta-analysis in CMAJ by a team of researchers from the University of East Anglia in the United Kingdom and Wake Forest University in the United States http://www.cmaj.ca/press/080486.pdf.

The drugs, called thiazolidinediones, help improve glycemic control and decrease insulin resistance in patients with diabetes.

Popular class of diabetes drugs doubles risk of fractures in women

WINSTON-SALEM, N.C. – New findings out of Wake Forest University School of Medicine and the University of East Anglia show that long-term use of a popular class of oral diabetic drugs doubles the risk of fractures in women with type 2 diabetes.

The findings appear online today on the Web site for the Canadian Medical Association Journal and will appear in the January 6 issue.

Flora not flourishing in world's hotspots

Researchers at the University of Calgary have found the biodiversity picture in the region known as the "lungs of the Earth" contradicts commonly held views relating to extinction in that area.

A paper published in PLoS ONE by Jana Vamosi and Steven Vamosi outlines that the risk of extinction for plants is higher in countries close to the equator than previously thought.

Echocardiography now recommended as the 'first-line' test in cardiovascular disease

The first-line test in patients with a suspicion of cardiovascular disease – including arterial disease and heart failure - should now be echocardiography, says Professor Jose Luis Zamorano, Chair of the Programme Committee for EUROECHO 2008 and EAE President-Elect.

EUROECHO 2008, which is now the world's largest scientific gathering on echocardiography, will take place in Lyon, France, from 10-13th December.

EUROECHO 2008 is the twelfth Annual Meeting of the European Association of Echocardiography, a registered branch of the European Society of Cardiology.

Asthma: Commonly used medication shows no clear benefits in children

There are no clear benefits to using long-acting beta2-agonists (LABAs) for treatment of asthma in children, a new study concludes. In an overview of recent Cochrane reviews, Child Health Field researchers report that there is currently insufficient evidence to suggest the drugs, which are recommended to relieve the symptoms of asthma, offer any additional benefit to conventional preventative medications.

Overweight siblings of children with type 2 diabetes likely to have abnormal blood sugar levels

Overweight siblings of children with type 2 diabetes are four times more likely to have abnormal glucose levels compared to other overweight children. Because abnormal glucose levels may indicate risk for diabetes or diabetes itself, these children could benefit from screening tests and diabetes prevention education.

Researchers from The Children's Hospital of Philadelphia published their findings today in the online edition of the Journal of Pediatrics.

Late Neandertals and modern human contact in southeastern Iberia

It is widely accepted that Upper Paleolithic early modern humans spread westward across Europe about 42,000 years ago, variably displacing and absorbing Neandertal populations in the process. However, Middle Paleolithic assemblages persisted for another 8,000 years in Iberia, presumably made by Neandertals. It has been unclear whether these late Middle Paleolithic Iberian assemblages were made by Neandertals, and what the nature of those humans might have been.

Nonhormonal treatment regimens improve survival in patients with metastatic breast cancer

Nonhormonal treatment regimens, including anthracycline-based regimens and taxanes, have improved overall survival in women with advanced (metastatic or recurrent inoperable) breast cancer over the last 35 years, according to a systematic review published December 9 in the Journal of the National Cancer Institute.

Numerous regimens have been tested in advanced breast cancer. However, each of the trials has compared only a few regimens, making it difficult for researchers and clinicians to know the relative merit of the individual regimens.