As bacteria resistant to commonly used antibiotics continue to increase in number, scientists keep searching for new sources of drugs. In this week's JBC, one potential new bactericide has been found in the tiny freshwater animal Hydra.
The protein identified by Joachim Grötzinger, Thomas Bosch and colleagues at the University of Kiel, hydramacin-1, is unusual (and also clinically valuable) as it shares virtually no similarity with any other known antibacterial proteins except for two antimicrobials found in another ancient animal, the leech.