Culture

A new "return to campus" survey led by The Ohio State University's Office of the Chief Wellness Officer finds rising rates of anxiety, depression, burnout and the use of unhealthy coping mechanisms among students navigating through a year affected by the COVID-19 pandemic, similar to other data on college students throughout the U.S.

Ohio State conducted surveys in August 2020 and April 2021 of randomly-selected students to assess changes in mental health, coping strategies, healthy lifestyle behaviors and needs over time. Among the 1,072 Ohio State students who responded:

Oncotarget published "Frame-shift mediated reduction of gain-of-function p53 R273H and deletion of the R273H C-terminus in breast cancer cells result in replication-stress sensitivity" which reported that these authors recently documented that gain-of-function mutant p53 R273H in triple negative breast cancer cells interacts with replicating DNA and PARP1.

SAN FRANCISCO, CA--July 22, 2021--To speed up a chemical reaction, a chemist might place the reactants over a Bunsen burner. Adding heat increases the degree of random movements and collisions of particles, accelerating the reaction.

In cell biology, one important "reaction" is the transformation of stem cells into all the other cells in the body, a process known as differentiation. Gladstone Institutes researchers have now discovered a molecular mechanism that acts like a Bunsen burner to "turn up the heat" and accelerate differentiation.

Researchers created a global dataset of job footprints in 50 countries and used a model to investigate how trying to meet the Paris Agreement global climate target of staying well below 2°C would affect energy sector jobs. They found that action to reach said target would increase net jobs by about 8 million by 2050, primarily due to gains in the solar and wind industries. The analysis appears July 23 in the journal One Earth.

Humid tropical forests, vital in global efforts to limit rising temperatures, are under threat as a result of changes in land use and climate. Now, researchers reporting in the journal One Earth on July 23 have developed a new way to keep tabs on the vulnerability of these forests on a global scale using satellite data. Called the tropical forest vulnerability index (TFVI), the hope is that this method will serve as an early warning for areas that are under the greatest threat to enable actions aimed at protecting these forests before it's too late.

Recently, a research group led by Prof. YUAN Kaijun and Prof. YANG Xueming from the Dalian Institute of Chemical Physics (DICP) of the Chinese Academy of Sciences revealed strong isotope effects in photodissociation of the water isotopologue (HOD) using the Dalian Coherent Light Source.

Their findings were published in Science Advances on July 23.

What The Study Did: Researchers investigated the association between net worth at midlife and subsequent longevity in individuals as well as with siblings and twins.

Authors: Eric D. Finegood, Ph.D., of Northwestern University in Evanston, Illinois, is the corresponding author.

To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ 

(doi:10.1001/jamahealthforum.2021.1652)

What The Study Did: Using survey responses from students in some Pittsburgh, Pennsylvania, high schools, researchers investigated how experiences of bullying based on race/ethnicity/national origin and other marginalized identities are associated with outcomes for health, mental health and violence among adolescents.

Authors: Chardée A. Galán, Ph.D., of the University of Pittsburgh, is the corresponding author.

Hershey, Pa. -- Financial instability, lack of infrastructure, a deteriorating sense of community and family fragmentation are key contributors to diseases of despair in Pennsylvania communities, according to Penn State College of Medicine and Highmark Health researchers. The researchers conducted four focus groups in Pennsylvania communities identified as having high rates of despair-related illnesses.

University of Virginia School of Medicine researchers have discovered a previously unknown repair process in the brain that they hope could be harnessed and enhanced to treat seizure-related brain injuries.

Common seizure-preventing drugs do not work for approximately a third of epilepsy patients, so new and better treatments for such brain injuries are much needed. UVA's discovery identifies a potential avenue, one inspired by the brain's natural immune response.

Many disease-causing bacteria such as Pseudomonas aeruginosa crawl on surfaces through a walk-like motility known as "twitching". Nanometers-wide filaments called type IV pili are known to power twitching, but scientists ignore which sensory signals coordinate the microbes' movements.

How does a view of nature gain its gloss of beauty? We know that the sight of beautiful landscapes engages the brain's reward systems. But how does the brain transform visual signals into aesthetic ones? Why do we perceive a mountain vista or passing clouds as beautiful? A research team from the Max Planck Institute for Empirical Aesthetics has taken up this question and investigated how our brains proceed from merely seeing a landscape to feeling its aesthetic impact.

Alexandria, Va., USA - Ruth Lipman, American Dental Association (ADA) Science and Research Institute, Chicago, Ill., U.S., presented the poster "Strategies for Disseminating Guidance to Dentists during the COVID-19 Pandemic" at the virtual 99th General Session & Exhibition of the International Association for Dental Research (IADR), held in conjunction with the 50th Annual Meeting of the American Association for Dental Research (AADR) and the 45th Annual Meeting of the Canadian Association for Dental Research (CADR), on July 21-24, 2021.

A new optogenetic tool, a protein that can be controlled by light, has been characterized by researchers at Ruhr-Universität Bochum (RUB). They used an opsin - a protein that occurs in the brain and eyes - from zebrafish and introduced it into the brain of mice. Unlike other optogenetic tools, this opsin is not switched on but rather switched off by light. Experiments also showed that the tool could be suitable for investigating changes in the brain that are responsible for the development of epilepsy.

As the SARS-CoV-2 virus that causes COVID-19 continues to evolve, immunologists and infectious diseases experts are eager to know whether new variants are resistant to the human antibodies that recognized initial versions of the virus. Vaccines against COVID-19, which were developed based on the chemistry and genetic code of this initial virus, may confer less protection if the antibodies they help people produce do not fend off new viral strains.