The neurodegeneration that occurs in Parkinson's disease is a result of stress on the endoplasmic reticulum in the cell rather than failure of the mitochondria as previously thought, according to a study in fruit flies. It was found that the death of neurons associated with the disease was prevented when chemicals that block the effects of endoplasmic reticulum stress were used.
Body
Previous exposure to the dengue virus may increase the potency of Zika infection, according to research from Imperial College London.
The early-stage laboratory findings, published in the journal Nature Immunology, suggests the recent explosive outbreak of Zika may have been driven in part by previous exposure to the dengue virus.
For 3 billion years, one of the major carriers of information needed for life, RNA, has had a glitch that creates errors when making copies of genetic information. Researchers at The University of Texas at Austin have developed a fix that allows RNA to accurately proofread for the first time. The new discovery, published June 23 in the journal Science, will increase precision in genetic research and could dramatically improve medicine based on a person's genetic makeup.
PITTSBURGH, June 23, 2016 - Potent doses of broccoli sprout extract activate a "detoxification" gene and may help prevent cancer recurrence in survivors of head and neck cancer, according to a trial by the University of Pittsburgh Cancer Institute, partner with UPMC CancerCenter, confirming preliminary results presented last year at the American Association for Cancer Research Annual Meeting.
People who visit parks for 30 minutes or more each week are much less likely to have high blood pressure or poor mental health than those who don't, according to new research by Australian and UK environmental scientists.
A study led by The University of Queensland (UQ) and the ARC Centre of Excellence for Environmental Decisions (CEED) suggests people might need a minimum "dose of nature".
UQ CEED researcher Dr Danielle Shanahan said parks offered health benefits including reduced risks of developing heart disease, stress, anxiety and depression.
Researchers at the Universitat Autònoma de Barcelona (UAB) with the collaboration of the Institute for Bioengineering of Catalonia (IBEC), led by the professor of the UAB Department of Genetics and Microbiology Esther Julián, announced one year ago that the cells of the Mycobacterium brumae offer an improved alternative to current bladder cancer treatments such as BCG (an immunotherapy based on the Mycobacterium bovis), which can cause infections.
Traditionally, the evolutionary development of an insect species has been explained by the notion that the female insect chooses her male partner based on size and other factors, so-called assortative mating. These mating patterns have also been believed to partially explain how the isolation between different species is maintained.
Coral cannot survive on its own for long. It needs to create a symbiotic relationship with algae to survive. Algae provides approximately 90 percent of the energy coral needs, which means that their partnership must be preserved in order to keep the coral healthy. In order to protect coral, algae, and the marine species that live in reef environments, scientists need to know more about how the symbiotic relationship between coral and algae begins. In collaboration with Amin Mohamed and Prof. David Miller at James Cook University, Prof. Noriyuki Satoh and Dr.
Eukaryotic microalgae are increasingly important for the sustainable production of environmental friendly, renewable biochemicals and biofuels. Recent technological advances in genomics and physiology of algae to produce industrially relevant products combined with advanced tools for genetic manipulation have enabled bioengineering of new strains of algae that heretofore had been impossible. The complexity of the eukaryotic genome (having nuclear, chloroplastic and mitochondrial genomes) provides challenges but opportunities that are not possible in prokaryotic systems.
The new stem cell-containing bio ink allows 3D printing of living tissue, known as bio-printing.
The new bio-ink contains two different polymer components: a natural polymer extracted from seaweed, and a sacrificial synthetic polymer used in the medical industry, and both had a role to play.
The synthetic polymer causes the bio-ink to change from liquid to solid when the temperature is raised, and the seaweed polymer provides structural support when the cell nutrients are introduced.
Plant development includes the initiation of structure patterning, and maturation as plants grow via cell division, elongation, and differentiation. Unlike animals that form all their body parts early in their life, plants constantly generate new structures from meristems in the apex, vascular, and cork cambium tissues throughout their lives. This process is regulated by interactions of endogenous genetic mechanisms and environmental stimuli.
New Haven, Conn. -- A Yale-led study describes how a known cancer gene, EGFR, silences genes that typically suppress tumors. The finding, published in Cell Reports, may lead to the development of more effective, individualized treatment for patients with lung cancer and other cancer types.
The first global mapping of artemisinin resistance (the KARMA study) has definitively confirmed that resistance to the main drug currently used in the treatment of Plasmodium falciparum malaria is for the moment confined to Southeast Asia and has not spread to sub-Saharan Africa. Led by researchers from both the Institut Pasteur in Paris and the Institut Pasteur in Cambodia, KARMA gathers a large consortium of institutions including 13 members of the Institut Pasteur International Network.
University of Utah biologists working in Turkey discovered two surprising facts about a group of 16 brown bears: First, six of the bears seasonally migrated between feeding and breeding sites, the first known brown bears to do so. Second, and more sobering, the other 10 bears stayed in one spot all year long: the city dump.
HOUSTON - (June 23, 2016) - A team led by Rice University scientists has improved the production of a potent anti-tumor antibiotic known as uncialamycin.
The Rice lab of synthetic chemist K.C. Nicolaou announced this month it had streamlined the total synthesis of uncialamycin to make it simpler to create novel variations of the molecule. Such variations could allow the substance, which is too toxic in its original form, to be made into useful drugs to fight cancer.
The new work by Nicolaou and colleagues appears in the Journal of the American Chemical Society.