DALLAS - June 24, 2016 - People who visit their primary care physicians are more likely to get potentially life-saving colon cancer screenings and follow up on abnormal stool blood test results - even in health systems that heavily promote mail-in home stool blood tests that don't require a doctor visit, a study involving UT Southwestern population health researchers shows.
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The use of medical marijuana for millions of patients suffering from a wide range of health conditions and the subsequent therapeutic benefits has long been documented. Twenty-three states, the District of Columbia, Puerto Rico, and Guam, have determined that Cannabis sativa (a.k.a. marijuana) can benefit patients suffering from a wide range of conditions, including cancer, epilepsy, chronic pain, and post-traumatic stress disorder.
Drug treatments for breast cancer patients might soon be designed based on the unique genetic autograph of their tumor.
As people get older, they become choosier about how they spend their time and with whom they spend it. Now, researchers reporting in the Cell Press journal Current Biology on June 23 find, based on a series of experimental and behavioral studies, that similar changes take place in Barbary macaques. The findings offer an evolutionary perspective on why aging humans behave as they do, according to the researchers.
Rabies virus (RABV) transmitted by dogs is responsible for an estimated 60,000 human deaths per year, especially in Asia and Africa. If humans bitten by a rabid animal are treated quickly, the disease can usually be prevented. Such post-exposure prophylaxis is expensive and should be reserved for bites from animals with confirmed infection, but testing dogs for rabies in resource-poor settings is challenging. A study published in PLOS NTDs reports that six commercially available rapid rabies tests--which could make testing dogs much easier--fail to reproducibly yield accurate results.
Finding out which is the highest mountain in the US Arctic may be the last thing on your mind, unless you are an explorer who skis from the tallest peaks around the globe. Ski mountaineer Kit DesLauriers joined forces with glaciologist Matt Nolan to settle a debate of more than 50 years, while testing a new, affordable mapping technique in a steep mountainous region. Their research is published today (23 June) in The Cryosphere, an open access journal of the European Geosciences Union (EGU).
Researchers have improved the integration of disparate sources and types of data which will advance scientists' understanding of disease using Wikipathways. This study, published in PLOS Computational Biology, will help other scientists better utilize open data and will aid the discovery of new therapeutic targets for disease.
Offering insights into a long-standing and mysterious bias in biology, a new study reveals how and why mitochondria are only passed on through a mother's egg - and not the father's sperm. What's more, experiments from the study show that when paternal mitochondria persist for longer than they should during development, the embryo is at greater risk of lethality. Harbored inside the cells of nearly all multicellular animals, plants and fungi are mitochondria, organelles that play an important role in generating the energy that cells need to survive.
Expression of a single gene can convert cells lining the seminal vesicle in the pelvis into prostate cells, a new study shows. The results provide a better understanding of the molecular mechanisms controlling the development of seminal vesicle and prostate tissues, which could provide valuable insights as to why cancer arises frequently in the latter but only rarely in seminal vesicles. Previous studies have found that loss of the gene Nkx3.1 results in impaired prostate differentiation in mice, prompting Aditya Dutta et al. to study the gene in greater detail.
A team of researchers have created a detailed computational model of the electrophysiology of congestive heart failure, a leading cause of death. This "virtual heart" could help medical researchers study new drug therapies - according to the study published in PLOS Computational Biology.
Washington, DC--Researchers have developed an index to better predict which women may experience faster bone loss across the menopause transition, according to a new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism.
Osteoporosis is often referred to as a "silent" disease because individuals who have it experience few noticeable symptoms. The progressive condition occurs when bones grow structurally weak and become more likely to fracture or break.
Scientists say good bacteria could be the key to keeping coral healthy, able to withstand the impacts of global warming and to secure the long-term survival of reefs worldwide.
"Healthy corals interact with complex communities of beneficial microbes or 'good bacteria'," says Dr. Tracy Ainsworth from the ARC Centre of Excellence for Coral Reef Studies at James Cook University who led the study. "It is very likely that these microorganisms play a pivotal role in the capacity of coral to recover from bouts of bleaching caused by rising temperatures."
Bottom line / takeaway message: The first and only study to look at isolate HIV-neutralizing antibodies from infants has found that novel antibodies that could protect against many variants of HIV can be produced relatively quickly after infection compared to adults. This suggests that various aspects of HIV-vaccine development, from design to administration, could be improved by mimicking infection and immune response in infants.
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NEW YORK, NY - June 23, 2016 - Mount Sinai scientists have identified a previously unknown mechanism by which a protein called CBX8 promotes tumor growth in the most lethal forms of breast cancer. The study, published today in the journal Cell Reports, underscores the need for cancer researchers to pay more attention to "epigenetic" factors, meaning chemical and biological processes that control gene expression without changing the underlying DNA sequence of the cells that are running amok.
Future medicine is bound to include extensive tissue-engineering technologies such as organs-on-chips and organoids - miniature organs grown from stem cells. But all this is predicated on a simple yet challenging task: controlling cellular behavior in three dimensions. So far, most cell culture approaches are limited to two-dimensional environments (e.g. a Petri dish or a chip), but that neither matches real biology nor helps us sculpt tissues and organs.