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At NYU Langone Medical Center the focus on quality, patient safety and patient experience are not just broad stroke initiatives – but measureable, quantifiable and concrete. Patients and health care professionals can learn about this commitment to world-class care and operational transparency in the Department of Orthopaedic Surgery's recently published "2012 Quality and Outcomes Report," which is now available online as well as in hard copy at the American Academy of Orthopaedic Surgeons (AAOS) meeting taking place this week in San Francisco.

The group of Prof. Dr. Ralf Erdmann at the Ruhr-Universität Bochum (Faculty of Medicine, Department of Systems Biochemistry) discovered a connection of peroxisomal protein import and receptor export. In the Journal of Biological Chemistry, they disclosed that enzymes only get imported into certain cell organelles (peroxisomes) upon coupling of their import to the recycling of their transport protein (receptor).

Multi-functional tool peroxisome

DURHAM, NC -- Researchers at Duke University Medical Center used new tools they developed to analyze knees and hips and discovered that osteoarthritic knee joints are in a constant state of repair, while hip joints are not.

"This suggests the knee has capacity for repair we didn't know about and the main treatment strategy probably would need to focus on turning off the breakdown of knee tissue," said Virginia Kraus, M.D., Ph.D., professor of Rheumatology and Immunology at Duke. "I was hugely surprised to find this."

CORVALLIS, Ore. – A new study has shown that boosting the estrogen levels of male garter snakes causes them to secrete the same pheromones that females use to attract suitors, and turned the males into just about the sexiest snake in the neighborhood – attracting dozens of other males eager to mate.

This experiment in the famed garter snake caverns of Manitoba, Canada, was one of the first in a field setting to ever quantify the effects of estrogen as a stimulant of pheromones, scientists said, in research just published in the Journal of Experimental Biology.

PHILADELPHIA – Researchers at the Rothman Institute at Jefferson have shown that local anesthesia delivered through a catheter in the joint, intraarticularly, may be more beneficial than traditional opioids such as morphine and Oxycontin for pain management following total knee replacement surgery.

DALLAS (February 10, 2012) — In a study to be presented today at the Society for Maternal-Fetal Medicine's annual meeting, The Pregnancy Meeting ™, in Dallas, Texas, researchers will report findings that indicate that for women with prior delivery via cesarean section the optimal timing of elective delivery for mother and baby is 39 weeks even after consideration of the risk with continuing pregnancy.

DALLAS (February 10, 2012) — In a study to be presented today at the Society for Maternal-Fetal Medicine's annual meeting, The Pregnancy Meeting ™, in Dallas, Texas, researchers will report findings that indicate that preterm birth interventions should be tailored for underlying risk factors and pathways.

DALLAS (February 10, 2012) — In a study to be presented today at the Society for Maternal-Fetal Medicine's annual meeting, The Pregnancy Meeting ™, in Dallas, Texas, researchers will report findings that indicate that massively parallel sequencing can be used to diagnose fetal aneuploidies, including Down syndrome, Edwards syndrome, Patau syndrome and Turner syndrome.

DALLAS (February 10, 2012) — In a study to be presented today at the Society for Maternal-Fetal Medicine's annual meeting, The Pregnancy Meeting ™, in Dallas, Texas, researchers will report findings that indicate that the risk of obstetric intervention is lower for women who deliver or intend to deliver outside of hospitals, but there are some higher risks for newborns intended for home births compared to hospital births.

Treatment of childhood obstructive sleep apnea syndrome (OSAS) with positive airway pressure (PAP) therapy improves a number of important neurobehavioral outcomes, according to a new study from the The Children's Hospital of Philadelphia.

Children and adolescents with obstructive sleep apnea had substantial improvements in attention, anxiety and quality of life after treatment with positive airway pressure (PAP)—a nighttime therapy in which a machine delivers a stream of air through a mask into the nose.

"The benefits occurred even when children didn't fully adhere to the treatment," said study leader Carole L. Marcus, M.D., a sleep specialist and director of the Sleep Center at The Children's Hospital of Philadelphia. The Sleep Center follows thousands of children and adolescents with sleep problems.

Arterial stiffness due to is a major contributor to cardiovascular disease but is very difficult to measure. It also can influence blood pressure readings since these rely on the time taken for arteries to return to normal volume and flow after compression. A new method for measuring arterial stiffness has been reported in BioMed Central's open access journal BioMedical Engineering OnLine. This simple, non-invasive, calculation is able to interpret standard oscillometric measurements to quantify both arterial stiffness and blood pressure simultaneously.

Inflammatory breast cancer (IBC) is the most lethal form of breast cancer . It spreads easily through the lymphatic and blood vessels, forming metastasis which can lead to multi-organ failure. New research published in BioMed Central's open access journal Cell Communication and Signaling demonstrates how IBC cells use IL-8, secreted as part of the anti-inflammatory response by a specific set of white blood cells (monocytes), to increase fibronectin expression.

Invasive species which have the potential to destroy biodiversity and influence global change could be tracked and controlled in the same way as wanted criminals, according to new research from Queen Mary, University of London.

Geographic profiling (GP) was originally developed as a statistical tool in criminology, where it uses the locations of linked crimes (for example murder, rape or arson) to identify the predicted location of the offender's residence. The technique is widely used by police forces and investigative agencies around the world.

Drivers who consume cannabis within three hours of driving are nearly twice as likely to cause a vehicle collision as those who are not under the influence of drugs or alcohol claims a paper published today on bmj.com.

The paper's authors, from Dalhousie University, reviewed nine studies with a total sample of 49,411 people to determine whether the consumption of cannabis increases the risk of a motor vehicle collision.