Scientists have developed a new method of replacing missing teeth with a bioengineered material generated from a person's own gum cells. Current implant-based methods of whole tooth replacement fail to reproduce a natural root structure and as a consequence of the friction from eating and other jaw movement, loss of jaw bone can occur around the implant. The research is led by Professor Paul Sharpe, an expert in craniofacial development and stem cell biology at King's College London and published in the Journal of Dental Research.
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HOUSTON - Endometrial cancer survivors are more likely to complete physical activity, and for longer durations, when their daily self-efficacy is higher, according to a study published online in the journal Health Psychology – a publication of the American Psychology Association.
To speed development and adoption of electronic health records (EHRs) for pediatrics, a group of experts from industry, academia and government convened by the National Institute of Standards and Technology (NIST) has focused its attention on three key audiences—records-system vendors and developers, small-group pediatric medical practices and children's hospitals.
BUFFALO, N.Y. – A genetic mutation that alters the kinetics of an ion channel in red blood cells has been identified as the cause behind a hereditary anemia, according to a paper (http://bit.ly/13LgCzc) published this month in the Proceedings of the National Academy of Sciences by University at Buffalo scientists and colleagues.
Tiny biomolecular chambers called nanopores that can be selectively heated may help doctors diagnose disease more effectively if recent research by a team at the National Institute of Standards and Technology (NIST), Wheaton College, and Virginia Commonwealth University (VCU) proves effective. Though the findings* may be years away from application in the clinic, they may one day improve doctors' ability to search the bloodstream quickly for indicators of disease—a longstanding goal of medical research.
Positive emotions are known to play a role in physical well-being, and stress is strongly linked to poor health, but is this strictly a "First World" phenomenon? In developing nations, is the fulfillment of basic needs more critical to health than how one feels? A new study shows that emotions do affect health around the world and may, in fact, be more important to wellness in low-income countries.
HERSHEY, Pa. -- Only about one in five central Pennsylvania women who have experienced intimate partner violence is asked or counseled by a health care provider about abuse, according to Penn State medicine and public health science researchers. Overall, approximately only one in nine women has received preventive counseling about violence and safety.
Jared M. O'Leary, M.D., of Brigham and Women's Hospital, Boston, and colleagues analyzed U.S. hospitalizations from 1998 through 2010 for children and adults with congenital heart disease. "There are more than 787,000 adults with congenital heart disease in the United States. Adults with congenital heart disease remain at risk for frequent hospitalizations," the authors write in a Research Letter published online by JAMA to coincide with its presentation at the American College of Cardiology's annual Scientific Sessions.
UNIVERSITY PARK, Pa. -- Farmers can make a profit selling their produce directly to local businesses, but they must not let possible new costs weaken their commitment to the new venture, according to an international team of researchers.
"We found that the farmers who really made a conscious decision to sell local and who made more of a commitment tended to do better than those who are just testing the waters with local direct selling," said Amit Sharma, associate professor of hospitality management, Penn State.
Viruses and genes interact in a way that may increase the risk of developing schizophrenia significantly. This happens already in the developing foetus.
An international team of scientists led by Aarhus University, Denmark, has made this discovery. As the first in the world, they scanned the entire genome of hundreds of sick and healthy people to see if there is an interaction between genes and a very common virus - cytomegalovirus - and to see whether the interaction influences the risk of developing schizophrenia.
And it does.
Researchers at the Ruhr Universität Bochum have developed a new method for attaching proteins to the surface of germanium crystals – for the first time also membrane proteins. This enables time-resolved tracking of the interactions between molecules using infrared spectroscopy in a way that is accurate down to atomic resolution. The method is applied in the EU project "Kinetics for Drug Discovery, K4DD", in which scientists explore the interplay of drugs and their interaction partners.
The fact that excess weight during pregnancy has negative consequences is not new information. A new study now concludes that the children of mothers obese before falling pregnant are four times more likely to have frequent wheezing, which is one of the symptoms of asthma, compared to the children of mothers weighing a normal weight.
AUGUSTA, Ga. – A signaling molecule that helps stem cells survive in the naturally low-oxygen environment inside the bone marrow may hold clues to helping the cells survive when the going gets worse with age and disease, researchers report.
They hope the findings, reported in PLOS ONE, will result in better therapies to prevent bone loss in aging and enhance success of stem cell transplants for a wide variety of conditions from heart disease to cerebral palsy and cancer.
A multi-institutional study has revealed that BRAF-positive metastatic malignant melanomas develop resistance to treatment with drugs targeting the BRAF/MEK growth pathway through a major change in metabolism. The findings, which will be published in Cancer Cell and have been released online, suggest a strategy to improve the effectiveness of currently available targeted therapies.
Patients with diseases such as diabetes suffer from painful wounds that take a long time to heal making them more susceptible to infections that could even lead to amputations. A*STAR's discovery paves the way for therapeutics to improve healing of such chronic wounds, which are a significant burden to patients.