People with multiple sclerosis (MS) who were treated with combination therapy did not see significant clinical benefit over those treated with single drug therapy, but combination therapy did reduce the development of new lesions, according to an international research team led by The Mount Sinai Medical Center. The findings, part of the largest-ever MS trial sponsored by the National Institutes of Health, are published in the March 11 issue of Annals of Neurology.
Body
CHAMPAIGN, Ill. — Fitness DVDs are a multimillion-dollar business, and those targeting adults over the age of 55 are a major part of the market. With names like "Boomers on the Move," "Stronger Seniors" and "Ageless Yoga," the programs promise much, but few have ever been rigorously tested.
When it comes to body shape, diet and exercise can only take us so far. Our body shape and geometry are largely determined by genetic factors. Genetics also have an impact on our body composition – including soft fat tissue and hard bone tissue – and can lead to excess fat or osteoporosis.
Their warning comes as the Chief Medical Officer launches the UK's Antimicrobial Resistance Strategy and Action Plan, reflecting the need for a clear change in our understanding of and response to antimicrobial resistance by the public, NHS and government.
Medical researchers at the University of Alberta have made a discovery that may explain how prion diseases, like chronic wasting disease and mad cow disease, adapt in order to spread between various types of animals.
The research team, led by neurologist Valerie Sim, discovered that a miniscule change in the prions' makeup appears to give the disease the ability to adapt – to mimic and recreate new strains with which it comes into contact. The team has been studying this area for two years.
URBANA – Researchers in the Evolutionary Bioinformatics Laboratory at the University of Illinois in collaboration with German scientists have been using bioinformatics techniques to probe the world of proteins for answers to questions about the origins of life.
Proteins are formed from chains of amino acids and fold into three-dimensional structures that determine their function. According to crop sciences professor Gustavo Caetano-Anollés, very little is known about the evolutionary drivers for this folding.
A team of Spanish and Argentinean researchers have verified that the distribution of the inhabitants in each Spanish province evolves in accordance with the maximum entropy principle in the field of physics. Therefore, this evolution is predictable. The results have allowed authors to put forward a 'socio-thermodynamic' theory that applies the laws of thermodynamics to collective human behaviour.
New Rochelle, NY, March 11, 2013–Consumption of energy drinks containing caffeine may have beneficial effects on exercise but probably not for mental function. The effects of pre-exercise caffeine consumption by trained cyclists on racing times and cognitive performance were measured and are reported in Journal of Caffeine Research, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers.
A recent clinical trial found that interferonβ-1a (INF) and glatiramer acetate (GA), two of the most commonly prescribed drugs for multiple sclerosis (MS), provide no additional clinical benefit when taken together. While findings published today in Annals of Neurology, a journal of the American Neurological Association and Child Neurology Society, suggest that taking both INF and GA together was not superior to GA monotherapy in reducing relapse risk; the combination therapy does appear to reduce new lesion activity and total lesion volume.
Families with a child completing elementary school this year are now preparing their registration for high school, a transition that is often stressful for children. A new program has demonstrated that it is possible to significantly reduce stress in some of these children thanks to a new educational tool designed under the leadership of Sonia Lupien, Director of the Centre for Studies on Human Stress (CSHS) and professor at the University of Montreal.
A team of researchers from the National University of Singapore (NUS) led by Professor Loh Kian Ping, Head of the Department of Chemistry at the NUS Faculty of Science, has successfully altered the properties of water, making it corrosive enough to etch diamonds. This was achieved by attaching a layer of graphene on diamond and heated to high temperatures. Water molecules trapped between them become highly corrosive, as opposed to normal water.
AMHERST, Mass. – For hundreds of years, naturalists and scientists have identified new species based on an organism's visible differences. But now, new genetic techniques are revealing that different species can show little, to no visible differences.
Many Europeans are fretting these days over what they eat, and whether horse meat might have adulterated their pork chops. Food fraud has been dominating headlines globally - calling for new policies in law enforcement and more robust methods for successful food identification and authentication. As companies and manufacturers resort to fraudulent practices to extract more cash from the gullible public, it is estimated that up to 7% of the consumer supply chain contains hidden ingredients (i.e. – not disclosed on the label).
These findings are the result of a new study carried out at the Norwegian Institute of Public Health. In the study, women who took folic acid supplements from four weeks before conception to eight weeks into pregnancy had a 40 per cent lower risk of giving birth to children with childhood autism (classic autism).
"It appears that the crucial time interval is from four weeks before conception to eight weeks into pregnancy," states Pål Surén, MD and doctoral fellow at the Norwegian Institute of Public Health.