Adenoid cystic carcinoma (ACC) is a slow-growing and often fatal malignancy that can occur at multiple organ site, but is most frequently found in the salivary glands.
The primary treatment is surgical removal; however, the majority of patients develop metastatic disease.
In the Journal of Clinical Investigation, researchers led by Andrew Futreal at the Wellcome Trust Sanger Institute in Cambridge, MA, performed a type of genetic sequencing known as whole exome sequencing of 24 ACC cases.
An important challenge for neuroscientists is to find cures for diseases that affect the central nervous system, such as autism, Alzheimer's, or Parkinson's disease.
For this purpose, researchers use several vertebrate species as model organisms. The zebrafish has recently received much attention because it has many advantages over other vertebrate models. For example, development of its nervous system can be followed from its earliest stages in naturally behaving individuals.
Stable survival rates were observed for HIV-associated lymphoma patients during the antiretroviral therapy (ART) era in the US, according to a new study published July 26 in the Journal of the National Cancer Institute.
PHILADELPHIA — Humans are far more than merely the sum total of all the cells that form the organs and tissues. The digestive tract is also home to a vast colony of bacteria of all varieties, as well as the myriad viruses that prey upon them. Because the types of bacteria carried inside the body vary from person to person, so does this viral population, known as the virome.
25th July 2013 - Scientists at A*STAR's Genome Institute of Singapore (GIS) led in a study that has identified genes that are potential targets for therapeutic drugs against aggressive breast cancer. These findings were reported in the July 2013 issue of PNAS.
Consumers are more likely to search for alternatives when they are given only one option, according to a new study in the Journal of Consumer Research.
"There has been a lot of recent attention devoted to the pitfalls of presenting consumers with too many options. However, consumers may also react negatively when choices are too restrictive. Isolating an option, even temporarily, may increase how much consumers search and potentially the likelihood that they make no purchase," writes author Daniel Mochon (Tulane University).
Companies that empower consumers by involving them in important processes such as product development shouldn't also try to influence them through social media, according to a new study in the Journal of Consumer Research.
"Peer-to-peer marketing and consumer empowerment may not be compatible. Empowered consumers resist social influence by either discounting the opinions of others or deliberately expressing opinions that diverge from those of other consumers," write authors Mehdi Mourali (University of Calgary) and Zhiyong Yang (University of Texas, Arlington).
Consumers set high prices when selling their possessions because they feel threatened, according to a new study in the Journal of Consumer Research.
"When consumers consider selling a product they own, they feel threatened by the impending loss. In order to counter this threat, they increase the product's value," write authors Promothesh Chatterjee (University of Kansas), Caglar Irmak (University of Georgia), and Randall L. Rose (University of South Carolina).
Brands do not necessarily need to present a clear, well-defined image in order to appeal to consumers, according to a new study in the Journal of Consumer Research. Consider the case of the Titanic.
Communication channels such as Facebook may be leading consumers to discuss more interesting products, according to a new study in the Journal of Consumer Research.
Increased use of digital communication is causing consumers to lose their inhibitions and "overshare" online, according to a new study in the Journal of Consumer Research.
"Sharing itself is not new, but consumers now have unlimited opportunities to share their thoughts, opinions, and photos, or otherwise promote themselves and their self-image online. Digital devices help us share more, and more broadly, then ever before," writes author Russell W. Belk (York University).
Despite being much-maligned, materialism is not always bad for consumers.
Loneliness may cause materialism, but the opposite is not necessarily true, according to a new study in the Journal of Consumer Research.
Akron, Ohio, July 25, 2013 — University of Akron researchers have developed new materials that function on a nanoscale, which could lead to the creation of lighter laptops, slimmer televisions and crisper smartphone visual displays.
Known as "giant surfactants" – or surface films and liquid solutions – the researchers, led by Stephen Z. D. Cheng, dean of UA's College of Polymer Science and Polymer Engineering, used a technique known as nanopatterning to combine functioning molecular nanoparticles with polymers to build these novel materials.
X chromosomes are very special genetic material. They differ in number between men and women. To achieve equality between sexes, one out of two X chromosomes in women is silenced. In flies, the opposite happens: in male flies, the only available X chromosome is highly activated, to compensate for the absence of the second X-chromosome. Researchers from the Max Planck Institute of Immunobiology and Epigenetics (MPI-IE) in Freiburg have now shown how the RNA molecules and proteins involved in the activation find and stick to each other.
Environmental consultants, research ecologists, nature conservation agencies, city managers, translators, and many others, all need to put names to plants at one time or another. The sources used often are not scientifically up-to-date, making it difficult to figure out the accepted name or proper vernacular to use in a vast country like Canada. The VASCAN database simplifies this task for all users.