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A new gene associated with disease severity in models of rheumatoid arthritis has been identified by researchers at the Icahn School of Medicine at Mount Sinai. The discovery could provide a new pathway for treatment and a way to measure the prognosis of patients diagnosed with the autoimmune condition.

A catheter based procedure to close a type of 'hole in the heart' followed by antiplatelet drugs (e.g. aspirin) should be recommended for patients under 60 years old, who have also had a stroke, say a panel of experts in The BMJ today.

The procedure involves slowly moving a catheter (a long, thin, flexible tube) into the heart to close the hole. Most guidelines currently advise against the closure procedure and instead recommend taking life long anti-clotting drugs to prevent further strokes.

Researchers from the Musculoskeletal Research Unit at the University of Bristol have identified the most important risk factors for developing severe infection after hip replacement. Patients who are under 60 years of age, males, those with chronic pulmonary disease, diabetes and a higher body mass index are at increased risk of having the joint replacement redone (known as revision) due to infection. The research also showed that some patients are at risk of early infection whilst others are more prone to late infection after hip replacement.

University of Manchester and Salford Royal NHS Trust scientists have developed a lamp which could treat chronic ulcers with light.

The Arthritis Research UK funded trial led by Dr Michael Hughes tested the therapy - which combines infrared, red and ultraviolet light - on finger ulcers caused by a condition called systemic sclerosis, where the immune system attacks the body's fingers and toes.

Alexandria, Va., USA - At the 96th General Session of the International Association for Dental Research (IADR), held in conjunction with the IADR Pan European Regional (PER) Congress, Paula Moynihan, Newcastle University, England, gave an oral presentation titled "Relationship Between Amount and Frequency of Sugars Intake by Children." The IADR/PER General Session & Exhibition is in London, England at the ExCeL London Convention Center from July 25-28, 2018.

TORONTO, July 25, 2018 - Engaging patients in the redesign of health care services can lead to reduced hospital admissions and more efficient and effective health care, a study led by a St. Michael's Hospital researcher suggests.

In their study, Engaging Patients to Improve Quality of Care: A Systematic Review, published today in Implementation Science, lead authors Dr. Yvonne Bombard and Dr. G. Ross Baker concluded that active engagement of patients can inform education, tools, planning and policy, and enhance health care service delivery and governance.

Alexandria, Va., USA - At the 96th General Session of the International Association for Dental Research (IADR), held in conjunction with the IADR Pan European Regional (PER) Congress, Yao Liu, China Medical University, Taiwan, Province of China gave an oral presentation titled "PD-1 is Required to Dental Pulp Stem Cell Properties." The IADR/PER General Session & Exhibition is in London, England at the ExCeL London Convention Center from July 25-28, 2018.

Alexandria, Va., USA - At the 96th General Session of the International Association for Dental Research (IADR), held in conjunction with the IADR Pan European Regional (PER) Congress, Tian Liang, Texas A&M University, Dallas, USA gave an oral presentation titled "Unfolded Protein Response (UPR) Is Associated With Dentinogenesis Imperfecta (DGI)." The IADR/PER General Session & Exhibition is in London, England at the ExCeL London Convention Center from July 25-28, 2018.

Alexandria, Va., USA - At the 96th General Session of the International Association for Dental Research (IADR), held in conjunction with the IADR Pan European Regional (PER) Congress, Caroline Shiboski, University of California, San Francisco, USA gave an oral presentation titled "Increased Caries Risk Among Perinatally HIV-infected Youth on Integrase Inhibitors." The IADR/PER General Session & Exhibition is in London, England at the ExCeL London Convention Center from July 25-28, 2018.

Alexandria, Va., USA - At the 96th General Session of the International Association for Dental Research (IADR), held in conjunction with the IADR Pan European Regional (PER) Congress, John Bartlett, The Ohio State University, Columbus, USA, gave an oral presentation titled "MMP20 May Initiate Enamel Formation via Basement Membrane Degradation." The IADR/PER General Session & Exhibition is in London, England at the ExCeL London Convention Center from July 25-28, 2018.