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Amsterdam, NL, December 10, 2019 - For patients with Huntington's disease (HD), clinical trials can offer hope when there are no treatments available despite unknowns about whether the therapy will work or is safe.
BOSTON - A new study led by Boston Medical Center uncovered a need to improve testing rates for Hepatitis C Virus (HCV) in young people, specifically those with documented substance use history. In the national data sample, under 30 percent of young patients who reported using opioids, methamphetamine, and/or cocaine were tested for HCV.
Tumor volume in a preclinical model of triple negative breast cancer (TNBC) was reduced four times more when an experimental polo-like kinase 1 (PLK1) inhibitor was combined with a standard-of-care chemotherapeutic agent than when the agent was used alone. Hollings Cancer Center scientists at the Medical University of South Carolina reported these findings in PLOS ONE.
Sometimes, the medications needed to function and live a quality life cause side effects that can make life quite uncomfortable.
Preventable deaths are those that can be stymied by public health intervention, and deaths related to tobacco use are at the top of that list in the United States as well as globally.
And while rates of adolescent smoking have declined over the years, 4.9 million middle and high school students reported using tobacco in 2018, according to the U.S. Department of Health and Human Services.
A new study suggests that specialized immune cells that dampen inflammation and help repair the gut could be used as a potential therapy for children dealing with the painful symptoms of inflammatory bowel disease (IBD).
The research from BC Children's Hospital and the University of British Columbia shows that a specific type of T cell, called a Tr1 cell, produces a chemical signal that helps repair the barrier formed by cells lining the gut and encourages the production of protective mucus. This study was published in the December issue of Gastroenterology.
London, UK: Cephalalgia, the official journal of the International Headache Society, published the article entitled "Cinnarizine and sodium valproate as the preventive agents of pediatric migraine: A randomized double-blind placebo-controlled trial", by Man Amanat, and Mahmoud Reza Ashrafi from the Tehran University of Medical Sciences, Tehran, Iran.
DALLAS - Dec. 10, 2019 - Federal regulations may keep lung cancer patients out of clinical trials simply because these patients are on medications that might affect the electrical system of the heart. Drilling into the details quickly turns up reasons to think these regulations may be preventing a substantial proportion of patients from participating in clinical trials. There may be alternatives, and researchers and physicians should explore them.
DES PLAINES, IL -- A study to evaluate the effect of an Electronic Medication Complete Communication (EMC2) Opioid Strategy on patients' safe use of and knowledge about opioids found that the EMC2 tools improved demonstrated safe dosing, but these benefits did not translate into actual use based on medication dairies.
Damage to energy-producing mitochondria may underlie prolonged muscle weakness following a sepsis-like condition in mice, according to a new study published today in eLife.
The findings may explain why humans struggle to regain strength after sepsis recovery, and suggest the need for antioxidant or other alternative treatments to restore muscle health.
About 32 percent of older, sicker patients enrolled on a leukemia clinical trial experienced serious side effects from a treatment that combined a chemotherapy and an immunotherapy drug, leading investigators to pause the trial and the U.S. Food and Drug Administration to eventually pull the combination from the current study.
Lancaster University researchers have discovered, for the first time, how a genetic alteration that increases the risk of developing Autism and Tourette's impacts on the brain.
Their research also suggests that ketamine, or related drugs, may be a useful treatment for both of these disorders.
Physicians use standard disease classifications based on symptoms or location in the body to help make diagnoses. These classifications, called nosologies, can help doctors understand which diseases are closely related, and thus may be caused by the same underlying issues or respond to the same treatments.
One-third of Americans rely on news platforms they acknowledge are less reliable, mainly social media and peers. The other two-thirds of the public consider their primary news sources trustworthy, mainly print news and broadcast television, according to a new RAND Corporation report.
BOSTON - While most U.S. infant and preschool-aged international travelers are eligible for measles-mumps-rubella (MMR) vaccination prior to departure, almost 60 percent of eligible young travelers were not vaccinated during pretravel consultation, researchers at Massachusetts General Hospital (MGH) have found. In a study published in JAMA Pediatrics, the team reported that most eligible pediatric international travelers were not vaccinated due to clinician decision or guardian refusal, despite recommendations from the Advisory Committee on Immunization Practices (ACIP).