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Pets on planes

The preferences of pet owners should not replace the well-being of their fellow passengers, states an editorial in CMAJ (Canadian Medical Association Journal) (pre-embargo link only) http://www.cmaj.ca/embargo/cmaj100100.pdf. Pets can be accommodated comfortably and safely in airplane cargo holds, which is where they belong. Airlines must choose to put the needs of their human passengers first, or be forced to do so.

Cell-cell interactions adapt to the stiffness of the environment

The ability of tissue cells to stick to one another is critical for many physiological and pathological processes. But normal living cells need to do much more than just hold on tight, they must monitor their environment and respond with appropriate changes in shape, migration, and proliferation. Now, a new study published online on February 16th by Cell Press in the Biophysical Journal provides intriguing insight into how mechanical interaction with the external environment influences cell shape and the forces generated by a cell's internal "skeleton".

Cancer publishes study confirming disparity in breast cancer treatment

WILMINGTON, Del.—Feb. 16, 2010—Cancer, the peer-reviewed international journal of the American Cancer Society, has published a study conducted by HealthCore, Inc. in its Jan. 1 edition, demonstrating disparities in breast cancer treatment between commercially insured African-American and white women.

The HealthCore study reiterates the findings of previous studies — conducted in populations using government health programs — that African-American women are diagnosed in later stages of the disease.

Butterfly vision, wing colors linked, UCI study finds

Irvine, Calif., Feb. 16, 2010 – Butterfly experts have suspected for more than 150 years that vision plays a key role in explaining wing color diversity. Now, for the first time, research led by UC Irvine biologists proves this theory true – at least in nine Heliconius species.

Low-cost DNA test to pinpoint risk of inherited diseases

An inexpensive, fast, accurate DNA test that reveals a person's risk of developing certain diseases is expected to become a reality, thanks to technology developed at the University of Edinburgh.

Scientists have developed a method of pinpointing variations in a person's genetic code at critical points along the DNA chain. The technique could be used to analyse DNA in a drop of saliva.

Stress and trade-offs explain life's diversity: New Smithsonian model

Plants and people alike face critical choices as they reproduce: to make a few big, well-provisioned seeds—or babies--or many small, poorly-provisioned ones. Different species make strikingly different choices, resulting in a great diversity of life forms: Darwin's "endless forms most beautiful.

Helene Muller-Landau, staff scientist at the Smithsonian Tropical Research Institute argues that these diverse strategies coexist because different levels of stress favor different choices.

Researchers identify mechanism for Frank-Ter Haar syndrome

LA JOLLA, Calif., February 12, 2010 – An international team of investigators at Sanford-Burnham Medical Research Institute (Sanford-Burnham, formerly Burnham Institute for Medical Research), Nijmegen Centre for Molecular Life Sciences and other organizations have discovered that TKS4, a protein implicated in cancer metastasis, also plays a significant role in Frank-Ter Haar syndrome (FTHS), a rare fatal disorder. The research was published on February 12 in the American Journal of Human Genetics.

AGA offers new recommendations for CRC surveillance for certain patients with IBD

Bethesda, MD (Feb. 16, 2010) — Certain patients with inflammatory bowel disease (IBD), both ulcerative colitis and Crohn's disease of the colon, have an increased risk of developing colorectal cancer compared to individuals without IBD. A number of factors contribute to the increase in risk, which necessitates an individualized and sensible approach to surveillance in patients, according to a new medical position statement and technical review published by the American Gastroenterological Association in its official journal, Gastroenterology.

Enzyme design with remote effects

Attacking cancer cells with hydrogel nanoparticles

One of the difficulties of fighting cancer is that drugs often hit other non-cancerous cells, causing patients to get sick. But what if researchers could sneak cancer-fighting particles into just the cancer cells? Researchers at the Georgia Institute of Technology and the Ovarian Cancer Institute are working on doing just that. In the online journal BMC Cancer they detail a method that uses hydrogels - less than 100 nanometers in size - to sneak a particular type of small interfering RNA(siRNA) into cancer cells.

Fetal surgery continues to advance

Repairing birth defects in the womb. Inserting a tiny laser into the mother's uterus to seal off an abnormal blood flow and save fetal twins. Advancing the science that may allow doctors to deliver cells or DNA to treat sickle cell anemia and other genetic diseases before birth.

Gastrointestinal absorption of Tamiflu in critically ill patients with H1N1

An increased dosage of Tamiflu (oseltamivir) for patients with critical illness is unlikely to be required in the treatment of pandemic (H1N1) influenza, contrary to current international guidelines, found a new study http://www.cmaj.ca/cgi/doi/10.1503/cmaj.092127 in CMAJ (Canadian Medical Association Journal) www.cmaj.ca.

Genomic warfare to counter malaria drug resistance

Montreal, February 16, 2010 – Scientists battling malaria have earned a major victory. According to a Nature Genetics study, an international group of researchers has used genomics to decode the blueprint of Plasmodium falciparum – a strain of malaria most resistant to drugs that causes the most deaths around the world. The discovery may lead to advanced pharmaceuticals to fight the disease and prevent drug resistance among the 250 million people infected by malaria each year.

Winter Olympics: Experts discuss altitude and performance

BLOOMINGTON, Ind. -- For winter sports athletes, including Olympians competing in Vancouver this week, the altitude of the sports venue can have a significant impact on performance, requiring athletes in skill sports, such as figure skating, ski jumping and snowboarding, to retool highly technical moves to accommodate more or less air resistance.

The putative skull of St. Bridget can be questioned

The putative skull of Saint Bridget (Birgitta) of Sweden that has been kept in a shrine in Vadstena Abbey is probably not authentic. A new study conducted at Uppsala University reveals that the two skulls, believed to be from Saint Bridget and her daughter Catherine (Katarina), is not from maternally related individuals. Furthermore, dating show that the skulls are not from the time period when Bridget and Catherine lived. The findings are published in the journal PLoS ONE.