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After making a diagnosis of cancer, clinicians have a number of treatment options. Most of these involve coordinating multiple attacks on the tumor using an arsenal of cancer-killing therapies. Chemotherapy, where toxic drugs are used to specifically kill cancer cells, is a very powerful weapon in this arsenal. It is extremely effective in treating some cancers, such as testicular cancer and Hodgkin's Disease, but works poorly in other cancer types.

TUSCALOOSA, Ala. – Discovery of an antibiotic's capacity to improve cell function in laboratory tests is providing movement disorder researchers with leads to more desirable molecules with potentially similar traits, according to University of Alabama scientists co-authoring a paper publishing March 10 in the journal Disease Models & Mechanisms.

A study on the past extinction of large mammals in India by the Wildlife Conservation Society, Duke University, and other groups has found that country's protected area system and human cultural tolerance for some species are key to conserving the subcontinent's tigers, elephants, and other large mammals.

According to the study, the long-term survival of many large species in the midst of rapid economic growth will require improving existing protected areas and establishing new protected areas and corridors.

Current drugs used to treat heart failure and arrhythmias (irregular heartbeat) have limited effectiveness and have side effects. New basic science findings from a University of Iowa study suggest a way that treatments could potentially be refined so that they work better and target only key heart-related mechanisms.

The domestication of animals and plants is the most important technological innovation during human history. This genetic transformation of wild species has occurred as humans have used individuals carrying favorable gene variants for breeding purposes. In the current issue of Nature an international team led by researchers at Uppsala University has revealed some of the secrets underlying the remarkable development of the domestic chicken.

We have known for several years that Hepatitis C, a common cause of liver cirrhosis and cancer, also makes people three to four times more likely to develop Type 2 diabetes.

In studying the insulin resistance of 29 people with Hepatitis C, Australian researchers have confirmed that they have high insulin resistance, a precursor to diabetes. However, almost all insulin resistance was in muscle, with little or none in the liver, a very surprising finding given that Hepatitis C is a liver disease.

Ann Arbor, Mich. — Patients with irritable bowel syndrome are at no greater risk of having polyps, colon cancer or inflammatory bowel diseases than healthy people undergoing colonoscopies, according to new research published in the American Journal of Gastroenterology.

"Patients and doctors get nervous about the symptoms of irritable bowel syndrome (IBS)," says William D. Chey, M.D., professor of Internal Medicine at the University of Michigan Medical School. "They think the symptoms represent something more sinister."

Scientists in Texas are reporting development of a first-of-its-kind cloth that releases nitric oxide gas — an advance toward making therapeutic socks for people with diabetes and a wrap to help preserve organs harvested for transplantation. The study is in ACS' Chemistry of Materials, a bi-weekly journal.

DALLAS – March 10, 2010 – Physicians may be able to safely lower the platelet dosage in transfusions for cancer and bone-marrow transplant patients without risking increased bleeding, according to new research involving UT Southwestern Medical Center and 28 other medical institutions.

Reducing platelet transfusions, and lowering the threshold on when to administer transfusions could help address frequent shortages in platelet supplies, said Dr. Victor Aquino, associate professor of pediatrics and an author of the study appearing in The New England Journal of Medicine.

STANFORD, Calif. — About four out of every 10 cells in the brain are so-called oligodendrocytes. These cells produce the all-important myelin that coats nerve tracts, ensuring fast, energy-efficient transmission of nerve impulses. Mixed among them are proliferating but not particularly proficient precursor cells that are destined to become oligodendrocytes when needed but, for now, remain suspended in an immature, relatively undifferentiated state somewhere between stem cell and adult oligodendrocyte.

Researchers from Delft University of Technology in the Netherlands have succeeded in making a significant leap forward in the production of biochemicals and biofuels from waste wood. They discovered that the bacterium Cupriavidus basilensis breaks down harmful by-products which are produced when sugars are released from wood. They also managed to incorporate the degradation process in bacteria which are in common industrial use.

Is it time for all community-based doctors to turn to e-prescribing to cut down on the number of medication errors? According to Rainu Kaushal and colleagues from the Weill Cornell Medical College in New York, electronic prescriptions can dramatically reduce prescribing errors – up to seven-fold. Their study¹ of the benefits of e-prescribing in primary care practices appears online in the Journal of General Internal Medicine², published by Springer.

Exposure to news media has long been thought to help create a more informed and politically educated citizenry, but a new University of Georgia study finds that media exposure did little to correct a significant misperception during the most recent presidential campaign.

KINGSTON, R.I. – March 10, 2010 – A 10-year effort by a University of Rhode Island scientist to develop transgenic rainbow trout with enhanced muscle growth has yielded fish with what have been described as six-pack abs and muscular shoulders that could provide a boost to the commercial aquaculture industry.

DURHAM, N.C. -- A study of extinction patterns of 25 large mammal species in India finds that improving existing protected areas, creating new areas, and interconnecting them will be necessary for many species to survive this century.